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Autoimmunity Volume 40, 2007 - Issue 2
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Original

Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren's syndrome and protect human salivary acinar cells from TNF-α-induced cytotoxicity

Stephen D. Hsu Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
Douglas P. Dickinson Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
Haiyan Qin Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
James Borke Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
Kalu U. E. Ogbureke Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
Julia N. Winger Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
Amy M. Camba Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
,
Wendy B. Bollag Medical College of Georgia, Institute of Molecular Medicine and Genetics, Augusta, GAUSA
,
Hubert J. Stöppler Medical College of Georgia, Institute of Molecular Medicine and Genetics, Augusta, GAUSA
,
Mohamed M. Sharawy Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
&
George S. Schuster Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GAUSA
 show all
Pages 138-147 | Received 03 Aug 2006, Accepted 08 Dec 2006, Published online: 07 Jul 2009

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Keiichi Saito, Shiro Mori, Fumiko Date & Guang Hong. (2015) Epigallocatechin gallate stimulates the neuroreactive salivary secretomotor system in autoimmune sialadenitis of MRL-Fas mice via activation of cAMP-dependent protein kinase A and inactivation of nuclear factor κB. Autoimmunity 48:6, pages 379-388.
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Keiichi Saito, Shiro Mori, Fumiko Date & Masao Ono. (2014) Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2. Autoimmunity 47:1, pages 13-22.
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Saeko Hoshikawa, Yoshinori Nakagawa, Hiroshi Ozaki, Yurie Takahashi, Sadayoshi Ito, Katsumi Yoshida & Kouki Mori. (2013) Effects of Green Tea Polyphenols on Iodide-Induced Autoimmune Thyroiditis In Nonobese Diabetic Mice. Immunological Investigations 42:3, pages 235-246.
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Seiji Ohno, Hongfang Yu, Douglas Dickinson, Tin-Chun Chu, Kalu Ogbureke, Scott Derossi, Tetsuya Yamamoto & Stephen Hsu. (2012) Epigallocatechin-3-gallate modulates antioxidant and DNA repair-related proteins in exocrine glands of a primary Sjogren's syndrome mouse model prior to disease onset. Autoimmunity 45:7, pages 540-546.
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Dayong Wu & Junpeng Wang. (2011) The ability of green tea to alleviate autoimmune diseases: fact or fiction?. Expert Review of Clinical Immunology 7:6, pages 711-713.
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Zahra Amirghofran, Katayoun Javidnia, Masood Bahmani, Abbas Azadmehr & Maryam Esmaeilbeig. (2011) THE EFFECT OF THE METHANOL EXTRACT OF GALIUM MITE ON THE CELLULAR IMMUNITY AND ANTIBODY SYNTHESIS. Journal of Immunoassay and Immunochemistry 32:3, pages 157-169.
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Mika MIYAKE, Kazuki IDE, Katsunori SASAKI, Yasuko MATSUKURA, Kumiko SHIJIMA & Daisuke FUJIWARA. (2008) Oral Administration of Highly Oligomeric Procyanidins of Jatoba Reduces the Severity of Collagen-Induced Arthritis. Bioscience, Biotechnology, and Biochemistry 72:7, pages 1781-1788.
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Joel J. Napeñas & Tanya S. Rouleau. (2014) Oral Complications of Sjögren's Syndrome. Oral and Maxillofacial Surgery Clinics of North America 26:1, pages 55-62.
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Jan-Eric Turner. (2011) Glomerulonephritis therapy: is there a role for green tea?. Kidney International 80:6, pages 563-564.
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Zhuo Fu, Wei Zhen, Julia Yuskavage & Dongmin Liu. (2010) Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice. British Journal of Nutrition 105:8, pages 1218-1225.
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Lisa A. Beltz. 2009. Herbal Drugs: Ethnomedicine to Modern Medicine. Herbal Drugs: Ethnomedicine to Modern Medicine 137 152 .
Kevin Gillespie, Isamu Kodani, Douglas P. Dickinson, Kalu U.E. Ogbureke, Amy M. Camba, Mengjie Wu, Stephen Looney, Tin-Chun Chu, Haiyan Qin, Frederick Bisch, Mohamed Sharawy, George S. Schuster & Stephen D. Hsu. (2008) Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren's syndrome, an autoimmune disease. Life Sciences 83:17-18, pages 581-588.
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Salahuddin Ahmed, Hubert Marotte, Kevin Kwan, Jeffrey H. Ruth, Phillip L. Campbell, Bradley J. Rabquer, Angela Pakozdi & Alisa E. Koch. (2008) Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production. Proceedings of the National Academy of Sciences 105:38, pages 14692-14697.
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Lorne J. Hofseth. (2008) Nitric oxide as a target of complementary and alternative medicines to prevent and treat inflammation and cancer. Cancer Letters 268:1, pages 10-30.
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J. Gupta, Y.H. Siddique, T. Beg, G. Ara & M. Afzal. (2008) A Review on the Beneficial Effects of Tea Polyphenols on Human Health. International Journal of Pharmacology 4:5, pages 314-338.
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S.A. Mathews, B.T. Kurien & R.H. Scofield. (2008) Oral Manifestations of Sjögren’s Syndrome. Journal of Dental Research 87:4, pages 308-318.
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