Advanced search
Publication Cover
Journal of Investigative Surgery Volume 17, 2004 - Issue 6
Submit an article Journal homepage
113
Views
26
CrossRef citations to date
0
Altmetric
Research Article

Selectin Inhibition Modulates Akt/MAPK Signaling and Chemokine Expression After Liver Ischemia–Reperfusion

Luis H. Toledo-Pereyra Borgess Research Institute, Trauma, Surgery Research Sciences and Molecular Biology, Departments of Surgery and Research, Michigan State University/Kalamazoo Center for Medical Studies, Kalamazoo, Michigan, Department of Surgery, Michigan State University, East Lansing, Michigan, USACorrespondence[email protected]
, MD, PhD,
Fernando Lopez-Neblina Borgess Research Institute, Trauma, Surgery Research Sciences and Molecular Biology, Kalamazoo, Michigan, USA
, MD, MS,
Jayne S. Reuben Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
, PhD,
Alexander H. Toledo Department of Surgery, University of Maryland, Baltimore, Maryland, USA
, MD &
Peter A. Ward Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
, MD
Pages 303-313 | Published online: 16 Apr 2010

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

Hossein-Ali Arab, Neal I. Walker, Kee Cheung, Peter E. Hickman, Jolia M. Potter, Mehri Kadkhodaee & Michael S. Roberts. (2015) Free Radical Scavengers Improve Liver Function but Not Morphological Changes Induced by Reperfusion Injury. Journal of Investigative Surgery 28:2, pages 77-85.
Read now
Roop Gill & Timothy R. Billiar. (2009) Hepatic dysfunction after shock: Clinical parameters and biological pathways for therapeutic intervention. Journal of Organ Dysfunction 5:1, pages 26-37.
Read now
Luis H. Toledo-Pereyra, Fernando Lopez-Neblina & Alexander H. Toledo. (2008) Protein Kinases in Organ Ischemia and Reperfusion. Journal of Investigative Surgery 21:4, pages 215-226.
Read now
Carolyn J. Mullonkal & Luis H. Toledo-Pereyra. (2007) Akt in Ischemia and Reperfusion. Journal of Investigative Surgery 20:3, pages 195-203.
Read now
Colleen R. Calvey & Luis H. Toledo-Pereyra. (2007) Selectin Inhibitors and Their Proposed Role in Ischemia and Reperfusion. Journal of Investigative Surgery 20:2, pages 71-85.
Read now
Luis H. Toledo-Pereyra, Fernando Lopez-Neblina, Alex B. Lentsch, Roberto Anaya-Prado, Suzanne J. Romano & Peter A. Ward. (2006) Selectin Inhibition Modulates NF-κ B and AP-1 Signaling After Liver Ischemia/Reperfusion. Journal of Investigative Surgery 19:5, pages 313-322.
Read now
Fernando Lopez-Neblina, Alexander H. Toledo & Luis H. Toledo-Pereyra. (2005) Molecular Biology of Apoptosis in Ischemia and Reperfusion. Journal of Investigative Surgery 18:6, pages 335-350.
Read now

Articles from other publishers (19)

Zhao-Qi Huang, Wei Xu, Jin-Lei Wu, Xiong Lu & Xi-Ming Chen. (2019) MicroRNA-374a protects against myocardial ischemia-reperfusion injury in mice by targeting the MAPK6 pathway. Life Sciences 232, pages 116619.
Crossref
Jiménez-Castro, Cornide-Petronio, Gracia-Sancho, Casillas-Ramírez & Peralta. (2019) Mitogen Activated Protein Kinases in Steatotic and Non-Steatotic Livers Submitted to Ischemia-Reperfusion. International Journal of Molecular Sciences 20:7, pages 1785.
Crossref
Matthias Bartneck, Christopher Thorsten Schlößer, Matthias Barz, Rudolf Zentel, Christian Trautwein, Twan Lammers & Frank Tacke. (2017) Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers. ACS Nano 11:10, pages 9689-9700.
Crossref
Fatemeh Fattahi, Miriam Kalbitz, Elizabeth A. Malan, Elizabeth Abe, Lawrence Jajou, Markus S. Huber‐Lang, Markus Bosmann, Mark W. Russell, Firas S. Zetoune & Peter A. Ward. (2017) Complement‐induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction. The FASEB Journal 31:9, pages 4129-4139.
Crossref
Xiaodong Weng, Min Wang, Hui Chen, Zhiyuan Chen & Xiuheng Liu. (2015) Ischemic postconditioning inhibits apoptosis of renal cells following reperfusion: a novel in vitro model. International Urology and Nephrology 47:7, pages 1067-1074.
Crossref
Theodore Karatzas, Anna-Aikaterini Neri, Maria-Eleni Baibaki & Ismene A. Dontas. (2014) Rodent models of hepatic ischemia–reperfusion injury: time and percentage-related pathophysiological mechanisms. Journal of Surgical Research 191:2, pages 399-412.
Crossref
Yue Gao, Yi Qiao, Donald L. Kreutzer & Yuri W. Novitsky. (2012) Decreased Expression of Hepatic Signaling Phosphoproteins After Laparoscopic and Hand-Assisted Surgery in a Porcine Model. Journal of Surgical Research 176:2, pages 608-613.
Crossref
R Bahde & H-U Spiegel. (2010) Hepatic ischaemia–reperfusion injury from bench to bedside. British Journal of Surgery 97:10, pages 1461-1475.
Crossref
Miao-Fang Yang, Jun Xie, Xiao-Yi Gu, Xiao-Hua Zhang, Andrew K Davey, Shuang-Jie Zhang, Ji-Ping Wang & Ren-Min Zhu. (2009) Involvement of 90-kuD ribosomal S6 kinase in collagen type I expression in rat hepatic fibrosis. World Journal of Gastroenterology 15:17, pages 2109.
Crossref
Luis H. Toledo-Pereyra, Alexander Horacio Toledo, Roberto Anaya-Prado & Fernando Lopez-Neblina. (2008) Antioxidants in ischemic disease*. Critical Care Medicine 36:12, pages 3275-3276.
Crossref
Roberto Anaya-Prado, Nahum Pérez-Gomez, Luis H. Toledo-Pereyra, John Walsh, Jackie Jordan & Peter A. Ward. (2008) Small Molecule Selectin Inhibitor in Global Cerebral Ischemia and Controlled Hemorrhagic Shock. Journal of Trauma: Injury, Infection & Critical Care 65:3, pages 678-684.
Crossref
Darren G Woodside & Peter Vanderslice. (2008) Cell Adhesion Antagonists. BioDrugs 22:2, pages 85-100.
Crossref
Charles C Caldwell, Johannes Tschoep & Alex B Lentsch. (2007) Lymphocyte function during hepatic ischemia/reperfusion injury. Journal of Leukocyte Biology 82:3, pages 457-464.
Crossref
Zhifeng Qi, Xiangning Bu, Ping Huang, Nan Zhang, Song Han, Li Fang & Junfa Li. (2007) Increased Membrane/Nuclear Translocation and Phosphorylation of p90 KD Ribosomal S6 Kinase in the Brain of Hypoxic Preconditioned Mice. Neurochemical Research 32:9, pages 1450-1459.
Crossref
Fernando López-Neblina & Luis H. Toledo-Pereyra. (2007) Anti-Ischemic Effect of Selectin Blocker Through Modulation of Tumor Necrosis Factor-α and Interleukin-10. Journal of Surgical Research 138:2, pages 275-283.
Crossref
Fernando López-Neblina & Luis H. Toledo-Pereyra. (2006) Phosphoregulation of Signal Transduction Pathways in Ischemia and Reperfusion. Journal of Surgical Research 134:2, pages 292-299.
Crossref
C. Jayle, S. Milinkevitch, F. Favreau, C. Doucet, J.P. Richer, S. Deretz, G. Mauco, H. Rabb & T. Hauet. (2006) Protective role of selectin ligand inhibition in a large animal model of kidney ischemia–reperfusion injury. Kidney International 69:10, pages 1749-1755.
Crossref
Sandya R. Govindaraju, Brian D. Curry, James L. W. Bain & Danny A. Riley. (2006) Effects of temperature on vibration-induced damage in nerves and arteries. Muscle & Nerve 33:3, pages 415-423.
Crossref
Hongtao Wang, Bhupinder P.S. Vohra, Yan Zhang & Robert O. Heuckeroth. (2005) Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice. Hepatology 42:5, pages 1099-1108.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.