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Inhalation Toxicology
International Forum for Respiratory Research
Volume 20, 2008 - Issue 3
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Original

Derivation of an Inhalation Reference Concentration Based upon Olfactory Neuronal Loss in Male Rats following Subchronic Acetaldehyde Inhalation

David C. Dorman CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA; College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27606, USA
,
Melanie F. Struve CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA; College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27606, USA
,
Brian A. Wong CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
,
Elizabeth A. Gross CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
,
Carl Parkinson CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
,
Gabrielle A. Willson EPL, Inc., Research Triangle Park, North Carolina, USA
,
Yu-Mei Tan CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
,
Jerry L. Campbell CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
,
Justin G. Teeguarden Pacific Northwest National Laboratory, Richland, Washington, USA
,
Harvey J. Clewell III CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
&
Melvin E. Andersen CIIT at The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, USA
 show all
Pages 245-256 | Received 10 Jul 2007, Accepted 02 Nov 2007, Published online: 06 Oct 2008

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Katy O. Goyak & R. Jeffrey Lewis. (2021) Application of adverse outcome pathway networks to integrate mechanistic data informing the choice of a point of departure for hydrogen sulfide exposure limits. Critical Reviews in Toxicology 51:3, pages 193-208.
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Sean M. Colby, Senthil Kabilan, Richard E. Jacob, Andrew P. Kuprat, Daniel R. Einstein & Richard A. Corley. (2016) Comparison of realistic and idealized breathing patterns in computational models of airflow and vapor dosimetry in the rodent upper respiratory tract. Inhalation Toxicology 28:4, pages 192-202.
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Waylon M. Weber, Dean A. Kracko, Mericka R. Lehman, Clinton M. Irvin, Lee F. Blair, Richard K. White, Janet M. Benson, Gary R. Grotendorst, Yung-Sung Cheng & Jacob D. McDonald. (2010) Inhalation exposure systems for the development of rodent models of sulfur mustard-induced pulmonary injury. Toxicology Mechanisms and Methods 20:1, pages 14-24.
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Justin G. Teeguarden, Matthew S. Bogdanffy, Tammie R. Covington, Cecilia Tan & Annie M. Jarabek. (2008) A PBPK Model for Evaluating the Impact of Aldehyde Dehydrogenase Polymorphisms on Comparative Rat and Human Nasal Tissue Acetaldehyde Dosimetry. Inhalation Toxicology 20:4, pages 375-390.
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Articles from other publishers (15)

Tunga Salthammer. (2023) Acetaldehyde in the indoor environment. Environmental Science: Atmospheres 3:3, pages 474-493.
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Abdullah AlMatrouk, Kayla Lemons, Tatsuya Ogura & Weihong Lin. 2011. Comprehensive Physiology. Comprehensive Physiology 2621 2644 .
Weihsueh A. Chiu & Greg M. Paoli. (2020) Recent Advances in Probabilistic Dose–Response Assessment to Inform Risk‐Based Decision Making. Risk Analysis 41:4, pages 596-609.
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Varsha Hande, Keith Teo, Prarthana Srikanth, Jane See Mei Wong, Swaminathan Sethu, Wilner Martinez- Lopez & Manoor Prakash Hande. (2021) Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 861-862, pages 503303.
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Luca Anna Bors, Ágnes Bajza, Míra Mándoki, Benedek József Tasi, György Cserey, Tímea Imre, Pál Szabó & Franciska Erdő. (2020) Modulation of nose-to-brain delivery of a P-glycoprotein (MDR1) substrate model drug (quinidine) in rats. Brain Research Bulletin 160, pages 65-73.
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Ronald N. Kostoff, Michael Aschner, Marina Goumenou & Aristidis Tsatsakis. (2020) Setting safer exposure limits for toxic substance combinations. Food and Chemical Toxicology 140, pages 111346.
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Minju Kim, Jieun Song, Kosuke Nishi, Kandhasamy Sowndhararajan & Songmun Kim. (2020) Changes in the Electroencephalographic Activity in Response to Odors Produced by Organic Compounds. Journal of Psychophysiology 34:1, pages 35-49.
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David C. Dorman. (2019) Use of Nasal Pathology in the Derivation of Inhalation Toxicity Values for Hydrogen Sulfide. Toxicologic Pathology 47:8, pages 1043-1048.
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Mary Beth Genter & Richard L. Doty. 2019. Smell and Taste. Smell and Taste 389 408 .
Richard A. Corley, Senthil Kabilan, Andrew P. Kuprat, James P. Carson, Richard E. Jacob, Kevin R. Minard, Justin G. Teeguarden, Charles Timchalk, Sudhakar Pipavath, Robb Glenny & Daniel R. Einstein. (2015) Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts. Toxicological Sciences 146:1, pages 65-88.
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Richard L. Doty. 2015. Occupational Neurology. Occupational Neurology 299 324 .
Thomas Brüning, Rüdiger Bartsch, Hermann Maximillian Bolt, Herbert Desel, Hans Drexler, Ursula Gundert-Remy, Andrea Hartwig, Rudolf Jäckh, Edgar Leibold, Dirk Pallapies, Albert W. Rettenmeier, Gerhard Schlüter, Gisela Stropp, Kirsten Sucker, Gerhard Triebig, Götz Westphal & Christoph van Thriel. (2014) Sensory irritation as a basis for setting occupational exposure limits. Archives of Toxicology 88:10, pages 1855-1879.
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R. Ballesteros, J. Guillén-Flores & J.D. Martínez. (2014) Carbonyl emission and toxicity profile of diesel blends with an animal-fat biodiesel and a tire pyrolysis liquid fuel. Chemosphere 96, pages 155-166.
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. (2013) Richtwerte für Acetaldehyd in der InnenraumluftIndoor air guide values for acetaldehyde. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 56:10, pages 1434-1447.
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A. Muttray, J. Gosepath, J. Brieger, A. Faldum, A. Pribisz, O. Mayer-Popken, D. Jung, B. Roßbach, W. Mann & S. Letzel. (2008) No acute effects of an exposure to 50 ppm acetaldehyde on the upper airways. International Archives of Occupational and Environmental Health 82:4, pages 481-488.
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