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Research Article

Evaluation of bilosomes as nanocarriers for transdermal delivery of tizanidine hydrochloride: in vitro and ex vivo optimization

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Pages 171-182 | Received 04 May 2018, Accepted 11 Sep 2018, Published online: 13 Nov 2018

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Read on this site (8)

Reem Abou Assi, Ibrahim M. Abdulbaqi, Siew Mei Tan, Habibah A. Wahab, Yusrida Darwis & Siok-Yee Chan. (2023) Breaking barriers: bilosomes gel potentials to pave the way for transdermal breast cancer treatment with Tamoxifen. Drug Development and Industrial Pharmacy 0:0, pages 1-12.
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Mohammed H. Elkomy, Shahira F. El Menshawe, Rasha M. Kharshoum, Amany M. Abdeltwab, Raghda R. S. Hussein, Doaa S. Hamad, Izzeddin Alsalahat & Heba M. Aboud. (2022) Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation. Drug Delivery 29:1, pages 2058-2071.
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Heba F Salem, Mohammed M Nafady, Adel A Ali, Nermeen M Khalil & Amani A Elsisi. (2022) Evaluation of Metformin Hydrochloride Tailoring Bilosomes as an Effective Transdermal Nanocarrier. International Journal of Nanomedicine 17, pages 1185-1201.
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Mohamed El-Nabarawi, Mohamed Nafady, Shahira Elmenshawe, Marwa Elkarmalawy & Mahmoud Teaima. (2021) Liver Targeting of Daclatasvir via Tailoring Sterically Stabilized Bilosomes: Fabrication, Comparative In Vitro/In Vivo Appraisal and Biodistribution Studies. International Journal of Nanomedicine 16, pages 6413-6426.
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Rawia M. Khalil, Ahmed Abdelbary, Silvia Kocova El Arini, Mona Basha, Hadeer A. El-Hashemy & Faten Farouk. (2021) Development of tizanidine loaded aspasomes as transdermal delivery system: ex-vivo and in-vivo evaluation. Journal of Liposome Research 31:1, pages 19-29.
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Ameeduzzafar Zafar, Nabil K. Alruwaili, Syed Sarim Imam, Omar Awad Alsaidan, Mohd Yasir, Mohammed M. Ghoneim, Sultan Alshehri, Md. Khalid Anwer, Alanood S. Almurshedi & Abdullah S. Alanazi. (2021) Development and evaluation of luteolin loaded pegylated bilosome: optimization, in vitro characterization, and cytotoxicity study. Drug Delivery 28:1, pages 2562-2573.
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Articles from other publishers (27)

Devika Nayak, Mahalaxmi Rathnanand & Vamshi Krishna Tippavajhala. (2023) Unlocking the Potential of Bilosomes and Modified Bilosomes: a Comprehensive Journey into Advanced Drug Delivery Trends. AAPS PharmSciTech 24:8.
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Ameeduzzafar Zafar, Mohd Yasir & Mohammad Khalid. (2023) Development of Piperine-Loaded Soft Binary Ethosomal Gel to Improve Transdermal Delivery: Box-Bhekhen Design Optimization, Ex-Vivo Permeation, and Antimicrobial Evaluation. Journal of Cluster Science.
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Himabindu Peddapalli & G.V Radha. (2023) Formulation and optimization of novel vesicular elastic carrier for transdermal delivery of lercanidipine for the treatment of hypertension. Materials Today: Proceedings.
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Tarek M. Ibrahim. (2023) Exploitation of transdermal nanobilosomal gel platforms for ameliorating anti-diabetic activity of empagliflozin following I-optimal design. Journal of Drug Delivery Science and Technology 84, pages 104455.
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Mona G. Sakr, Sally A. El-Zahaby, Abdulaziz M. Al-Mahallawi & Dalia M. Ghorab. (2023) Fabrication of betaxolol hydrochloride-loaded highly permeable ocular bilosomes (HPOBs) to combat glaucoma: In vitro, ex vivo & in vivo characterizations. Journal of Drug Delivery Science and Technology 82, pages 104363.
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Mostafa Mohamed Younis, Noha Abd El-Fattah Fadel, Asmaa Badawy Darwish & Amira Mohamed Mohsen. (2023) Nanospanlastics as a Novel Approach for Improving the Oral Delivery of Resveratrol in Lipopolysaccharide-Induced Endotoxicity in Mice. Journal of Pharmaceutical Innovation.
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Heba F. Salem, Ghada Abdelsabour Moubarak, Adel A. Ali, Abeer A.A. Salama & Alaa H. Salama. (2023) Budesonide-Loaded Bilosomes as a Targeted Delivery Therapeutic Approach Against Acute Lung Injury in Rats. Journal of Pharmaceutical Sciences 112:3, pages 760-770.
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Syed Sarim Imam, Sadaf Jamal Gilani, Ameeduzzafar Zafar, May Nasser Bin Jumah & Sultan Alshehri. (2023) Formulation of Miconazole-Loaded Chitosan–Carbopol Vesicular Gel: Optimization to In Vitro Characterization, Irritation, and Antifungal Assessment. Pharmaceutics 15:2, pages 581.
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Amira Mohamed Mohsen, Hadeer Ahmed El-Hashemy, Abeer Salama & Asmaa Badawy Darwish. (2022) Formulation of tizanidine hydrochloride–loaded provesicular system for improved oral delivery and therapeutic activity employing a 23 full factorial design. Drug Delivery and Translational Research 13:2, pages 580-592.
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El-Sayed Khafagy, Bjad K. Almutairy & Amr Selim Abu Lila. (2023) Tailoring of Novel Bile Salt Stabilized Vesicles for Enhanced Transdermal Delivery of Simvastatin: A New Therapeutic Approach against Inflammation. Polymers 15:3, pages 677.
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Samer Khalid Ali & Entidhar Jasim Muhammed Al-Akkam. (2023) Oral nanobilosomes of ropinirole: preparation, compatibility and Ex-vivo intestinal absorption study. Journal of Advanced Pharmacy Education and Research 13:4, pages 8-15.
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Mariam Zewail, Passent M. E. Gaafar, Nancy Abdel Hamid Abou Youssef, Merhan E. Ali, Mai F. Ragab, Miranda F. Kamal, Mohamed H. Noureldin & Haidy Abbas. (2022) Novel Siprulina platensis Bilosomes for Combating UVB Induced Skin Damage. Pharmaceuticals 16:1, pages 36.
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Maha A. MarzoukAsmaa M. ElbakryRawia M. KhalilAreej W. Zahran. (2022) Carvedilol- loaded Transdermal Ethosomal gel: Characterization, ex vivo/in vivo Evaluation. Research Journal of Pharmacy and Technology, pages 4017-4023.
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Tamer M. Mahmoud, Mohamed M. Nafady, Hanan O. Farouk, Dina M. Mahmoud, Yasmin M. Ahmed, Randa Mohammed Zaki & Doaa S. Hamad. (2022) Novel Bile Salt Stabilized Vesicles-Mediated Effective Topical Delivery of Diclofenac Sodium: A New Therapeutic Approach for Pain and Inflammation. Pharmaceuticals 15:9, pages 1106.
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Yasmin M. Ahmed, Raha Orfali, Doaa S. Hamad, Mostafa E. Rateb & Hanan O. Farouk. (2022) Sustainable Release of Propranolol Hydrochloride Laden with Biconjugated-Ufasomes Chitosan Hydrogel Attenuates Cisplatin-Induced Sciatic Nerve Damage in In Vitro/In Vivo Evaluation. Pharmaceutics 14:8, pages 1536.
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Mohammed H. Elkomy, Nabil K. Alruwaili, Mohammed Elmowafy, Khaled Shalaby, Ameeduzzafar Zafar, Naveed Ahmad, Izzeddin Alsalahat, Mohammed M. Ghoneim, Essam M. Eissa & Hussein M. Eid. (2022) Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation. Pharmaceutics 14:3, pages 563.
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Abeer Salama, Hadeer A. El-Hashemy & Asmaa Badawy Darwish. (2022) Formulation and optimization of lornoxicam-loaded bilosomes using 23 full factorial design for the management of osteoarthritis in rats: Modulation of MAPK/Erk1 signaling pathway. Journal of Drug Delivery Science and Technology 69, pages 103175.
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Mayssa Abdel Hady, Asmaa B. Darwish, Mohamed S. Abdel-Aziz & Ossama M. Sayed. (2022) Design of transfersomal nanocarriers of nystatin for combating vulvovaginal candidiasis; A different prospective. Colloids and Surfaces B: Biointerfaces 211, pages 112304.
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Haidy Abbas, Nesrine S. El Sayed, Merhan E. Ali & Manal A. Elsheikh. (2022) Integrated lecithin–bile salt nanovesicles as a promising approach for effective skin delivery of luteolin to improve UV-induced skin damage in Wistar Albino rats. Colloids and Surfaces B: Biointerfaces 211, pages 112299.
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Ameeduzzafar Zafar, Syed Sarim Imam, Nabil K. Alruwaili, Mohd Yasir, Omar Awad Alsaidan, Sultan Alshehri, Mohammed M. Ghoneim, Mohammad Khalid, Ali Alquraini & Salman S. Alharthi. (2022) Formulation and Evaluation of Topical Nano-Lipid-Based Delivery of Butenafine: In Vitro Characterization and Antifungal Activity. Gels 8:2, pages 133.
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Despoina Despotopoulou, Nefeli Lagopati, Stergios Pispas, Maria Gazouli, Costas Demetzos & Natassa Pippa. (2022) The technology of transdermal delivery nanosystems: from design and development to preclinical studies. International Journal of Pharmaceutics 611, pages 121290.
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Dipak Kumar Gupta, Abdul Ahad, Ayesha Waheed, Mohd. Aqil, Fahad I. Al-Jenoobi & Abdullah M. Al-Mohizea. 2022. Systems of Nanovesicular Drug Delivery. Systems of Nanovesicular Drug Delivery 293 309 .
Mahfoozur Rahman, Kainat Alam, Sarwar Beg, Deeksha Chauhan, Vikas Kumar, Abdul Hafeez, Ankit Sahoo, Waleed H. Almalki & Mohammad Javed Ansari. 2022. Nanotherapeutics in Cancer Vaccination and Challenges. Nanotherapeutics in Cancer Vaccination and Challenges 1 12 .
Faten Farouk, Rawia M. Khalil, Ahmed Abdelbary, Silvia Kocova El Arini, Mona Basha & Hadeer A. El-Hashemy. (2020) Bioanalytical Comparison of Transdermal Delivery of Tizanidine from Different Nanovesicular Carriers. Journal of Pharmaceutical Innovation 16:2, pages 384-390.
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Indhu A. Chacko, Vivek M. Ghate, Leonna Dsouza & Shaila A. Lewis. (2020) Lipid vesicles: A versatile drug delivery platform for dermal and transdermal applications. Colloids and Surfaces B: Biointerfaces 195, pages 111262.
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Amira Mohamed Mohsen, Abeer Salama & Ahmed Alaa Kassem. (2020) Development of acetazolamide loaded bilosomes for improved ocular delivery: Preparation, characterization and in vivo evaluation. Journal of Drug Delivery Science and Technology 59, pages 101910.
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Sarwar Beg, Khalid S Alharbi, Nabil K Alruwaili, Nasser Hadal Alotaibi, Waleed H Almalki, Sattam K Alenezi, Waleed M Altowayan, Mohammed S Alshammari & Mahfoozur Rahman. (2020) Nanotherapeutic systems for delivering cancer vaccines: recent advances. Nanomedicine 15:15, pages 1527-1537.
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