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Original

3α-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period

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Pages 268-279 | Published online: 07 Jul 2009

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Read on this site (5)

Katherine McEvoy & Lauren M. Osborne. (2019) Allopregnanolone and reproductive psychiatry: an overview. International Review of Psychiatry 31:3, pages 237-244.
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Philippe Nuss. (2015) Anxiety disorders and GABA neurotransmission: a disturbance of modulation. Neuropsychiatric Disease and Treatment 11, pages 165-175.
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Jean-Loup Rault, Kate Plush, Tamara Yawno & Pieter Langendijk. (2015) Allopregnanolone and social stress: regulation of the stress response in early pregnancy in pigs. Stress 18:5, pages 569-577.
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N. Pluchino, A. Santoro, E. Casarosa, J.-M. Wenger, A. D. Genazzani, P. Petignat & A. R. Genazzani. (2013) Advances in neurosteroids: role in clinical practice. Climacteric 16:sup1, pages 8-17.
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Articles from other publishers (79)

Doodipala Samba Reddy. (2023) Neuroendocrine insights into neurosteroid therapy for postpartum depression. Trends in Molecular Medicine 29:12, pages 979-982.
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Semra Etyemez, Kristen N. Miller, Kristin M. Voegtline, İpek Özdemir, Lindsay R. Standeven, Luca Spiro Santovito, Graziano Pinna, Jennifer L. Payne & Lauren M. Osborne. (2023) Metabolites of progesterone in pregnancy: Associations with perinatal anxiety. Psychoneuroendocrinology 156, pages 106327.
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Doodipala Samba Reddy, Robert H. Mbilinyi & Emily Estes. (2023) Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid replacement therapy. Psychopharmacology.
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Marie Vadstrup Pedersen, Line Mathilde Brostrup Hansen, Ben Garforth, Paul J. Zak & Michael Winterdahl. (2023) Adrenocorticotropic hormone secretion in response to anticipatory stress and venepuncture: The role of menstrual phase and oral contraceptive use. Behavioural Brain Research 452, pages 114550.
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Leah C Susser, Sharon Parish, Emily Dumas & Rossella E Nappi. (2023) Premenstrual dysphoric disorder and sexual function: a narrative review. Sexual Medicine Reviews 11:3, pages 202-211.
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Morgan L Sherer, Abid Malik, Lauren M Osborne, Armaan A Rowther, Ahmed Zaidi, Najia Atif, Atif Rahman, Lubna E Kahloon, Muhammad Salman, Gayane Yenokyan & Pamela J Surkan. (2023) Biological Mechanisms in Pregnant Women With Anxiety (Happy Mother-Healthy Baby Supplement Study): Protocol for a Longitudinal Mixed Methods Observational Study. JMIR Research Protocols 12, pages e43193.
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Małgorzata Stefaniak, Ewa Dmoch-Gajzlerska, Katarzyna Jankowska, Artur Rogowski, Anna Kajdy & Radosław B. Maksym. (2023) Progesterone and Its Metabolites Play a Beneficial Role in Affect Regulation in the Female Brain. Pharmaceuticals 16:4, pages 520.
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Ming-Te Lee, Roisin McNicholas, Lawrence Miall, Nigel Simpson, Kevin C.W. Goss, Nicola J. Robertson & Paul Chumas. (2023) Progesterone as a Neuroprotective Agent in Neonatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review. Developmental Neuroscience 45:2, pages 76-93.
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Leah C. Susser. (2023) Clinical Implications of the Neurosteroid Allopregnanolone in Reproductive Depression. Harvard Review of Psychiatry 31:1, pages 37-45.
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Gabriella B MAYNE, Peter E DeWITT, Brandy RINGHAM, Anna G WARRENER, Uwe CHRISTIANS, Dana DABELEA & K Joseph HURT. (2023) A Nested Case-Control Study of Allopregnanolone and Preterm Birth in the Healthy Start Cohort. Journal of the Endocrine Society 7:2.
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Dana Bakalar, Jiaqi J. O’Reilly, Helene Lacaille, Jacquelyn Salzbank, Jacob Ellegood, Jason P. Lerch, Toru Sasaki, Yuka Imamura, Kazue Hashimoto-Torii, Claire-Marie Vacher & Anna A. Penn. (2022) Lack of placental neurosteroid alters cortical development and female somatosensory function. Frontiers in Endocrinology 13.
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Ying Sze & Paula J. Brunton. (2022) Neurosteroids and early-life programming: An updated perspective. Current Opinion in Endocrine and Metabolic Research 25, pages 100367.
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Delia Belelli, Grant D. Phillips, John R. Atack & Jeremy J. Lambert. (2021) Relating neurosteroid modulation of inhibitory neurotransmission to behaviour. Journal of Neuroendocrinology 34:2.
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Handan Gunduz‐Bruce, Koji Takahashi & Ming‐Yi Huang. (2021) Development of neuroactive steroids for the treatment of postpartum depression. Journal of Neuroendocrinology 34:2.
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Milos Markovic & Srdjan Milovanovic. (2022) Peripartum depression: Current considerations on classification, biological importance and therapeutic potential of neuroactive steroids. Vojnosanitetski pregled Military Medical and Pharmaceutical Journal of Serbia 79:12, pages 1255-1261.
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Jodie E. Pestana, Tayla B. McCutcheon, Sylvia K. Harmon-Jones, Rick Richardson & Bronwyn M. Graham. (2021) Maternal Experience Does Not Predict Fear Extinction and Anxiety-Like Behaviour in Primiparous Rats Post-weaning. Frontiers in Global Women's Health 2.
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Elizabeth S. Wenzel, Graziano Pinna, Tory Eisenlohr-Moul, Beatriz Penalver Bernabe, Raquel Romay Tallon, Unnathi Nagelli, John Davis & Pauline M. Maki. (2021) Neuroactive steroids and depression in early pregnancy. Psychoneuroendocrinology 134, pages 105424.
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Tomasz Misztal, Patrycja Młotkowska, Elżbieta Marciniak, Katarzyna Roszkowicz-Ostrowska & Anna Misztal. (2021) Involvement of neurosteroids in the control of hypothalamic-pituitary-adrenal axis activity in pregnant sheep under basal and stressful conditions. Theriogenology 174, pages 114-120.
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G. Mayne, E. De Bloois, D. Dabelea & U. Christians. (2021) Development and validation of an LC-MS/MS assay for the quantification of allopregnanolone and its progesterone-derived isomers, precursors, and cortisol/cortisone in pregnancy. Analytical and Bioanalytical Chemistry 413:21, pages 5427-5438.
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Shiyi Chen, Lijuan Gao, Xiaoyu Li & Yiping Ye. (2021) Allopregnanolone in mood disorders: Mechanism and therapeutic development. Pharmacological Research 169, pages 105682.
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Yekta Dowlati & Jeffrey H. Meyer. (2020) Promising leads and pitfalls: a review of dietary supplements and hormone treatments to prevent postpartum blues and postpartum depression. Archives of Women's Mental Health 24:3, pages 381-389.
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Saya Kikuchi, Natsuko Kobayashi, Zen Watanabe, Chiaki Ono, Takashi Takeda, Hidekazu Nishigori, Nobuo Yaegashi, Takahiro Arima, Kunihiko Nakai & Hiroaki Tomita. (2021) The delivery of a placenta/fetus with high gonadal steroid production contributes to postpartum depressive symptoms. Depression and Anxiety 38:4, pages 422-430.
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Julia C. Shaw, Gabrielle K. Crombie, Hannah K. Palliser & Jonathan J. Hirst. (2021) Impaired Oligodendrocyte Development Following Preterm Birth: Promoting GABAergic Action to Improve Outcomes. Frontiers in Pediatrics 9.
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Lindsay R. Standeven, Katherine O. McEvoy & Lauren M. Osborne. (2020) Progesterone, reproduction, and psychiatric illness. Best Practice & Research Clinical Obstetrics & Gynaecology 69, pages 108-126.
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Jennifer K. Torgersen, Rose Petitti, Sedric Tello, Vincent F. Lembo & Cheryl A. Frye. (2020) Prenatal resident-intruder stress decreases levels of allopregnanolone in the cortex, hypothalamus, and midbrain of males, and increases levels in the hippocampus and cerebellum of female, juvenile rat offspring. Neurobiology of Stress 12, pages 100214.
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Delia Belelli, Derk Hogenkamp, Kelvin W. Gee & Jeremy J. Lambert. (2020) Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor. Neurobiology of Stress 12, pages 100207.
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J. Verbe, C. Dubertret, W. El-Hage, F. Bonnet-Brilhault & P. Duriez. (2020) Approche GABAergique de la dépression du post-partum : une revue critique translationnelle. L'Encéphale 46:2, pages 123-134.
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Antonella Rosario Ramona Cáceres, Adriana Soledad Vega Orozco, Ricardo Jorge Cabrera & Myriam Raquel Laconi. (2020) “Rapid actions of the neurosteroid allopregnanolone on ovarian and hypothalamic steroidogenesis: Central and peripheral modulation”. Journal of Neuroendocrinology 32:3.
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Handan Gunduz-Bruce. (2020) Zuranolone—An Investigational Oral Neuroactive Steroid and Positive Allosteric Modulator of GABA Type A Receptors for Postpartum Depression and Major Depressive Disorder. US Neurology 16:2, pages 81.
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Tomasz Misztal, Marian R. Czauderna, Patrycja Młotkowska, Anna Misztal & Elżbieta Marciniak. (2020) Temporal changes in the cerebrospinal fluid allopregnanolone concentration and hypothalamic-pituitary-adrenal axis activity in sheep during pregnancy and early lactation. Livestock Science 231, pages 103871.
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Marie Bendix, Marie Bixo, Anna-Carin Wihlbäck, Antti Ahokas & Jussi Jokinen. (2019) Allopregnanolone and progesterone in estradiol treated severe postpartum depression and psychosis – Preliminary findings. Neurology, Psychiatry and Brain Research 34, pages 50-57.
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Trevor M Penning, Phumvadee Wangtrakuldee & Richard J Auchus. (2019) Structural and Functional Biology of Aldo-Keto Reductase Steroid-Transforming Enzymes. Endocrine Reviews 40:2, pages 447-475.
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Clare S. Burke, Leah C. Susser & Alison D. Hermann. (2018) GABAA dysregulation as an explanatory model for late-onset postpartum depression associated with weaning and resumption of menstruation. Archives of Women's Mental Health 22:1, pages 55-63.
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Katherine McEvoy, Jennifer L. Payne & Lauren M. Osborne. (2018) Neuroactive Steroids and Perinatal Depression: a Review of Recent Literature. Current Psychiatry Reports 20:9.
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Julia C. Shaw, Hannah K. Palliser, Rebecca M. Dyson, Mary J. Berry & Jonathan J. Hirst. (2017) Disruptions to the cerebellar GABAergic system in juvenile guinea pigs following preterm birth. International Journal of Developmental Neuroscience 65:1, pages 1-10.
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A. L. Cumberland, H. K. Palliser, P. Rani, D. W. Walker & J. J. Hirst. (2017) Effects of combined IUGR and prenatal stress on the development of the hippocampus in a fetal guinea pig model. Journal of Developmental Origins of Health and Disease 8:5, pages 584-596.
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Lauren M. Osborne, Fiona Gispen, Abanti Sanyal, Gayane Yenokyan, Samantha Meilman & Jennifer L. Payne. (2017) Lower allopregnanolone during pregnancy predicts postpartum depression: An exploratory study. Psychoneuroendocrinology 79, pages 116-121.
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Angela L. Cumberland, Hannah K. Palliser, Gabrielle K. Crombie, David W. Walker & Jonathan J. Hirst. (2017) Increased anxiety‐like phenotype in female guinea pigs following reduced neurosteroid exposure in utero . International Journal of Developmental Neuroscience 58:1, pages 50-58.
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Angela L. Cumberland, Hannah K. Palliser, David W. Walker & Jonathan J. Hirst. (2016) Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation. The Cerebellum 16:2, pages 306-313.
Crossref
S.S. Smith & H. Shen. 2017. Hormones, Brain and Behavior. Hormones, Brain and Behavior 245 258 .
Kristina M. Deligiannidis, Aimee R. Kroll-Desrosiers, Shunyan Mo, Hien P. Nguyen, Abby Svenson, Nina Jaitly, Janet E. Hall, Bruce A. Barton, Anthony J. Rothschild & Scott A. Shaffer. (2016) Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology 70, pages 98-107.
Crossref
P. Porcu, A. M. Barron, C. A. Frye, A. A. Walf, S.-Y. Yang, X.-Y. He, A. L. Morrow, G. C. Panzica & R. C. Melcangi. (2016) Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research. Journal of Neuroendocrinology 28:2.
Crossref
H. K. Palliser, M. A. Kelleher, M. Tolcos, D. W. Walker & J. J. Hirst. (2015) Effect of postnatal progesterone therapy following preterm birth on neurosteroid concentrations and cerebellar myelination in guinea pigs. Journal of Developmental Origins of Health and Disease 6:4, pages 350-361.
Crossref
Kurt D. Pennell, Mark A. Woodin & Page B. Pennell. (2015) Quantification of neurosteroids during pregnancy using selective ion monitoring mass spectrometry. Steroids 95, pages 24-31.
Crossref
Crystal Edler Schiller, Peter J. Schmidt & David R. Rubinow. (2014) Allopregnanolone as a mediator of affective switching in reproductive mood disorders. Psychopharmacology 231:17, pages 3557-3567.
Crossref
Patrizia Porcu & A. Leslie Morrow. (2014) Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies. Psychopharmacology 231:17, pages 3257-3272.
Crossref
Francesca Santoru, Roberta Berretti, Andrea Locci, Patrizia Porcu & Alessandra Concas. (2014) Decreased allopregnanolone induced by hormonal contraceptives is associated with a reduction in social behavior and sexual motivation in female rats. Psychopharmacology 231:17, pages 3351-3364.
Crossref
Georgina MacKenzie & Jamie Maguire. (2014) The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders. Psychopharmacology 231:17, pages 3333-3342.
Crossref
Mo Chen & Trevor M. Penning. (2014) 5β-Reduced steroids and human Δ4-3-ketosteroid 5β-reductase (AKR1D1). Steroids 83, pages 17-26.
Crossref
A. L. Cumberland, H. K. Palliser & J. J. Hirst. (2014) Increased placental neurosteroidogenic gene expression precedes poor outcome in the preterm guinea pig. Journal of Developmental Origins of Health and Disease 5:2, pages 74-78.
Crossref
M. Schumacher, C. Mattern, A. Ghoumari, J.P. Oudinet, P. Liere, F. Labombarda, R. Sitruk-Ware, A.F. De Nicola & R. Guennoun. (2014) Revisiting the roles of progesterone and allopregnanolone in the nervous system: Resurgence of the progesterone receptors. Progress in Neurobiology 113, pages 6-39.
Crossref
Paula J. Brunton, John A. Russell & Jonathan J. Hirst. (2014) Allopregnanolone in the brain: Protecting pregnancy and birth outcomes. Progress in Neurobiology 113, pages 106-136.
Crossref
Jonathan J. Hirst, Meredith A. Kelleher, David W. Walker & Hannah K. Palliser. (2014) Neuroactive steroids in pregnancy: Key regulatory and protective roles in the foetal brain. The Journal of Steroid Biochemistry and Molecular Biology 139, pages 144-153.
Crossref
Michael C. Byrns. (2014) Regulation of progesterone signaling during pregnancy: Implications for the use of progestins for the prevention of preterm birth. The Journal of Steroid Biochemistry and Molecular Biology 139, pages 173-181.
Crossref
Meredith A. Kelleher, Jonathan J. Hirst & Hannah K. Palliser. (2013) Changes in Neuroactive Steroid Concentrations After Preterm Delivery in the Guinea Pig. Reproductive Sciences 20:11, pages 1365-1375.
Crossref
Sirkku E. Jäntti, Minna Hartonen, Mika Hilvo, Heli Nygren, Tuulia Hyötyläinen, Raimo A. Ketola & Risto Kostiainen. (2013) Steroid and steroid glucuronide profiles in urine during pregnancy determined by liquid chromatography–electrospray ionization-tandem mass spectrometry. Analytica Chimica Acta 802, pages 56-66.
Crossref
Wen Jin, Michael Jarvis, Michal Star-Weinstock & Margaret Altemus. (2013) A sensitive and selective LC-differential mobility-mass spectrometric analysis of allopregnanolone and pregnanolone in human plasma. Analytical and Bioanalytical Chemistry 405:29, pages 9497-9508.
Crossref
Alyssa M McEwen, Denee T A Burgess, Christopher C Hanstock, Peter Seres, Panteha Khalili, Stephen C Newman, Glen B Baker, Nicholas D Mitchell, Janisse Khudabux-Der, Peter S Allen & Jean-Michel LeMelledo. (2012) Increased Glutamate Levels in the Medial Prefrontal Cortex in Patients with Postpartum Depression. Neuropsychopharmacology 37:11, pages 2428-2435.
Crossref
Patrizia Porcu, Maria Cristina Mostallino, Cristiana Sogliano, Francesca Santoru, Roberta Berretti & Alessandra Concas. (2012) Long-term administration with levonorgestrel decreases allopregnanolone levels and alters GABAA receptor subunit expression and anxiety-like behavior. Pharmacology Biochemistry and Behavior 102:2, pages 366-372.
Crossref
Susan S. Girdler, Monica Lindgren, Patrizia Porcu, David R. Rubinow, Jacqueline L. Johnson & A. Leslie Morrow. (2012) A history of depression in women is associated with an altered GABAergic neuroactive steroid profile. Psychoneuroendocrinology 37:4, pages 543-553.
Crossref
Cleofina Bosco & Eugenia Diaz. (2012) Placental Hypoxia and Foetal Development Versus Alcohol Exposure in Pregnancy. Alcohol and Alcoholism 47:2, pages 109-117.
Crossref
J. J. Paris, P. J. Brunton, J. A. Russell, A. A. Walf & C. A. Frye. (2011) Inhibition of 5α-Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring. Journal of Neuroendocrinology 23:11, pages 1079-1090.
Crossref
Cheryl A. Frye. (2011) Progesterone attenuates depressive behavior of younger and older adult C57/BL6, wildtype, and progesterone receptor knockout mice. Pharmacology Biochemistry and Behavior 99:4, pages 525-531.
Crossref
M. HILL, A. PAŘÍZEK, R. KANCHEVA & J. E. JIRÁSEK. (2011) Reduced Progesterone Metabolites in Human Late Pregnancy. Physiological Research, pages 225-241.
Crossref
Andrea Riccardo Genazzani, Fiorella Bucci, Natalia Russo, Diana Daino, Anna Natalizia Santoro & Nicola Pluchino. (2011) Neurosteroids in clinical practice: implications for women’s health. Hormone Molecular Biology and Clinical Investigation 7:3.
Crossref
Martin Hill, Antonín Pařízek, David Cibula, Radmila Kancheva, Jan Evangelista Jirásek, Marie Jirkovská, Marta Velíková, Jana Kubátová, Michaela Klímková, Andrea Pašková, Zdeněk Žižka, Lyudmila Kancheva, Hana Kazihnitková, Ludmila Zamrazilová & Luboslav Stárka. (2010) Steroid metabolome in fetal and maternal body fluids in human late pregnancy. The Journal of Steroid Biochemistry and Molecular Biology 122:4, pages 114-132.
Crossref
Martin Hill, Antonín Pařízek, Radmila Kancheva, Michaela Dušková, Marta Velíková, Lubomír Kříž, Michaela Klímková, Andrea Pašková, Zdeněk Žižka, Petr Matucha, Milan Meloun & Luboslav Stárka. (2010) Steroid metabolome in plasma from the umbilical artery, umbilical vein, maternal cubital vein and in amniotic fluid in normal and preterm labor. The Journal of Steroid Biochemistry and Molecular Biology 121:3-5, pages 594-610.
Crossref
Martin Hill, Antonín Pařízek, Marta Velíková, Jana Kubátová, Radmila Kancheva, Michaela Dušková, Kateřina Šimůnková, Michaela Klímková, Andrea Pašková, Zdeněk Žižka, Jan Evangelista Jirásek, Marie Jirkovská & Luboslav Stárka. (2010) The distribution of placental oxidoreductase isoforms provides different milieus of steroids influencing pregnancy in the maternal and fetal compartment. Hormone Molecular Biology and Clinical Investigation 4:3.
Crossref
Cheryl A Frye. (2009) Progestogens influence cognitive processes in aging. Future Medicinal Chemistry 1:7, pages 1215-1231.
Crossref
S.S. Smith & H. Shen. 2009. Hormones, Brain and Behavior. Hormones, Brain and Behavior 1561 1580 .
Jason J Paris & Cheryl A Frye. (2008) Estrous cycle, pregnancy, and parity enhance performance of rats in object recognition or object placement tasks. REPRODUCTION 136:1, pages 105-115.
Crossref
Peter W. Kaplan, Errol R. Norwitz, Elinor Ben-Menachem, Page B. Pennell, Maurice Druzin, Julian N. Robinson & Jacki C. Gordon. (2007) Obstetric risks for women with epilepsy during pregnancy. Epilepsy & Behavior 11:3, pages 283-291.
Crossref
Sheryl S. Smith, Hui Shen, Qi Hua Gong & Xiangping Zhou. (2007) Neurosteroid regulation of GABAA receptors: Focus on the α4 and δ subunits. Pharmacology & Therapeutics 116:1, pages 58-76.
Crossref
Ethan H. Beckley & Deborah A. Finn. (2007) Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility. Pharmacology Biochemistry and Behavior 87:4, pages 412-419.
Crossref
Martin Hill, David Cibula, Helena Havlíková, Lyudmila Kancheva, Tomáš Fait, Radmila Kancheva, Antonín Pařízek & Luboslav Stárka. (2007) Circulating levels of pregnanolone isomers during the third trimester of human pregnancy. The Journal of Steroid Biochemistry and Molecular Biology 105:1-5, pages 166-175.
Crossref
Marie-Laure Ancelin, Jacqueline Scali & Karen Ritchie. (2007) Hormonal therapy and depression: Are we overlooking an important therapeutic alternative?. Journal of Psychosomatic Research 62:4, pages 473-485.
Crossref
Deborah A. Finn & Robert H. Purdy. 2007. Handbook of Contemporary Neuropharmacology. Handbook of Contemporary Neuropharmacology.
Ming-De Wang, Mozibur Rahman, Di Zhu, Inga-Maj Johansson & Torbjörn Bäckström. (2007) 3β-hydroxysteroids and pregnenolone sulfate inhibit recombinant rat GABAA receptor through different channel property. European Journal of Pharmacology 557:2-3, pages 124-131.
Crossref
Zenab Amin, Graeme F. Mason, Idil Cavus, John H. Krystal, Douglas L. Rothman & C. Neill Epperson. (2006) The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women. Pharmacology Biochemistry and Behavior 84:4, pages 635-643.
Crossref

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