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Gynecological Endocrinology Volume 25, 2009 - Issue 10
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Review

Levonorgestrel-releasing Intrauterine System – The discontinuing story

Ayman A. A. Ewies Obstetrics and Gynaecology Department, The Ipswich Hospital NHS Trust, Ipswich, Suffolk, UKCorrespondence[email protected] [email protected]
Pages 668-673 | Received 24 Apr 2009, Accepted 22 Jun 2009, Published online: 15 Sep 2009

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Othman Kakaire, Nazarius Mbona Tumwesigye, Josaphat Kayogoza Byamugisha & Kristina Gemzell-Danielsson. (2016) Acceptability of intrauterine contraception among women living with human immunodeficiency virus: a randomised clinical trial. The European Journal of Contraception & Reproductive Health Care 21:3, pages 220-226.
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Articles from other publishers (29)

Elin Stenhammar, Per Wikman, Kristina Gemzell Danielsson, Helena Kopp-Kallner & Inger Sundström Poromaa. (2023) Levonorgestrel intrauterine device and depression: A Swedish register-based cohort study. International Journal of Psychophysiology 193, pages 112230.
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Ramune Griksiene, Rasa Monciunskaite & Osvaldas Ruksenas. (2022) What is there to know about the effects of progestins on the human brain and cognition?. Frontiers in Neuroendocrinology 67, pages 101032.
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MJ Brink, P Beelen, MC Herman, PM Geomini, JH Dekker, KM Vermeulen, MY Bongers & MY Berger. (2021) The levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding: a cost‐effectiveness analysis. BJOG: An International Journal of Obstetrics & Gynaecology 128:12, pages 2003-2011.
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Zoé Bürger, Anna Magdalena Bucher, Erika Comasco, Melanie Henes, Stephanie Hübner, Lydia Kogler & Birgit Derntl. (2021) Association of levonorgestrel intrauterine devices with stress reactivity, mental health, quality of life and sexual functioning: A systematic review. Frontiers in Neuroendocrinology 63, pages 100943.
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Isabella Claure, Deborah Anderson, Catherine M. Klapperich, Wendy Kuohung & Joyce Y. Wong. (2019) Biomaterials and Contraception: Promises and Pitfalls. Annals of Biomedical Engineering 48:7, pages 2113-2131.
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Hui Zhao, Baojun Yang, Limin Feng, Haixia Li, Hongyu Shang, Zhanqi Zhao & Yinmei Dai. (2020) Comparison of Combined Bipolar Radiofrequency Impedance-Controlled Endometrial Ablation with Levonorgestrel Intrauterine System versus Bipolar Radiofrequency Endometrial Ablation Alone in Women with Abnormal Uterine Bleeding. Journal of Minimally Invasive Gynecology 27:3, pages 774-780.
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Georgios A. Maragkos, Rouzbeh Motiei-Langroudi, Aristotelis S. Filippidis & Efstathios Papavassiliou. (2019) Intracranial hypertension after Chiari decompression resolving after removal of a levonorgestrel-releasing intrauterine device: case report. Journal of Neurosurgery 131:4, pages 1000-1003.
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Agota Malmborg, Jan Brynhildsen & Mats Hammar. (2019) A survey of young women’s perceptions of the influence of the Levonorgestrel-Intrauterine System or copper-intrauterine device on sexual desire. Sexual & Reproductive Healthcare 21, pages 75-80.
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Jim Slattery, Daniel Morales, Luis Pinheiro & Xavier Kurz. (2018) Cohort Study of Psychiatric Adverse Events Following Exposure to Levonorgestrel-Containing Intrauterine Devices in UK General Practice. Drug Safety 41:10, pages 951-958.
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Marian J. van den Brink, Pleun Beelen, Malou C. Herman, Nathalie J.J. Claassen, Marlies Y. Bongers, Peggy M. Geomini, Jan Willem van der Steeg, Lotte van den Wijngaard & Madelon van Wely. (2018) Women’s preferences for the levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding. European Journal of Obstetrics & Gynecology and Reproductive Biology 228, pages 143-147.
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Abimbola Famuyide. (2018) Endometrial Ablation. Journal of Minimally Invasive Gynecology 25:2, pages 299-307.
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Jurate Aleknaviciute, Joke H.M. Tulen, Yolanda B. De Rijke, Christian G. Bouwkamp, Mark van der Kroeg, Mirjam Timmermans, Vincent L. Wester, Veerle Bergink, Witte J.G. Hoogendijk, Henning Tiemeier, Elisabeth F.C. van Rossum, Cornelis G. Kooiman & Steven A. Kushner. (2017) The levonorgestrel-releasing intrauterine device potentiates stress reactivity. Psychoneuroendocrinology 80, pages 39-45.
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Georgy Joy Eralil. (2016) The Effectiveness of Levonorgestrel-Releasing Intrauterine System in the Treatment of Heavy Menstrual Bleeding. The Journal of Obstetrics and Gynecology of India 66:S1, pages 505-512.
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Mine Kiseli, Fulya Kayikcioglu, Ozlem Evliyaoglu & Ali Haberal. (2016) Comparison of Therapeutic Efficacies of Norethisterone, Tranexamic Acid and Levonorgestrel-Releasing Intrauterine System for the Treatment of Heavy Menstrual Bleeding: A Randomized Controlled Study. Gynecologic and Obstetric Investigation 81:5, pages 447-453.
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Natalie S Whaley & Anne E Burke. (2015) Intrauterine Contraception. Women's Health 11:6, pages 759-767.
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Elizabeth A Micks & Jeffrey T Jensen. (2015) Permanent Contraception for Women. Women's Health 11:6, pages 769-777.
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Janesh K Gupta, Jane P Daniels, Lee J Middleton, Helen M Pattison, Gail Prileszky, Tracy E Roberts, Sabina Sanghera, Pelham Barton, Richard Gray & Joe Kai. (2015) A randomised controlled trial of the clinical effectiveness and cost-effectiveness of the levonorgestrel-releasing intrauterine system in primary care against standard treatment for menorrhagia: the ECLIPSE trial. Health Technology Assessment 19:88, pages 1-118.
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Mahyar Etminan, Hao Luo & Paul Gustafson. (2015) Risk of intracranial hypertension with intrauterine levonorgestrel. Therapeutic Advances in Drug Safety 6:3, pages 110-113.
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Byung Seok LeeXu LingShaheena AsifPeter KraemerJens Ulrich HanischPirjo InkiJung Eun Lee. (2015) Therapy of heavy menstrual bleeding in Korea: Subanalysis and results from a multinational clinical trial in the Asian region investigating the levonorgestrel-releasing intrauterine system versus conventional therapy. Obstetrics & Gynecology Science 58:2, pages 162.
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Jenny A. Higgins & Anne R. Davis. (2014) Contraceptive sex acceptability: a commentary, synopsis and agenda for future research. Contraception 90:1, pages 4-10.
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Pierre Clerson, Olivier Graesslin, Adam Gater, Fiona Taylor, Anna Filonenko, Ilka Schellschmidt & Kimberly Rosen. (2014) EVAPIL-R Scale: Continuous Development and Validation of a Tool to Assess Patient-Reported Tolerability of Different Contraceptive Methods in Longitudinal Studies. Clinical Therapeutics 36:5, pages 638-647.e3.
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Malou C Herman, Marian J van den Brink, Peggy M Geomini, Hannah S van Meurs, Judith A Huirne, Heleen P Eising, Anne Timmermans, Johanna MA Pijnenborg, Ellen R Klinkert, Sjors F Coppus, Theodoor E Nieboer, Ruby Catshoek, Lucet F van der Voet, Hugo WF van Eijndhoven, Giuseppe CM Graziosi, Sebastiaan Veersema, Paul J van Kesteren, Josje Langenveld, Nicol AC Smeets, Huib AAM van Vliet, Jan Willem van der Steeg, Yvonne Lisman-van Leeuwen, Janny H Dekker, Ben W Mol, Marjolein Y Berger & Marlies Y Bongers. (2013) Levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation (Novasure) in women with heavy menstrual bleeding: a multicentre randomised controlled trial. BMC Women's Health 13:1.
Crossref
Byung S. Lee, Xu Ling, Shaheena Asif, Peter Kraemer, Jens U. Hanisch & Pirjo Inki. (2013) Levonorgestrel-releasing intrauterine system versus conventional medical therapy for heavy menstrual bleeding in the Asia-Pacific region. International Journal of Gynecology & Obstetrics 121:1, pages 24-30.
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Uma Thiruchelvam, Ian Dransfield, Philippa T K Saunders & Hilary O D Critchley. (2013) The importance of the macrophage within the human endometrium. Journal of Leukocyte Biology 93:2, pages 217-225.
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Janesh Gupta, Joe Kai, Lee Middleton, Helen Pattison, Richard Gray & Jane Daniels. (2013) Levonorgestrel Intrauterine System versus Medical Therapy for Menorrhagia. New England Journal of Medicine 368:2, pages 128-137.
Crossref
Elena Toffol, Oskari Heikinheimo, Päivikki Koponen, Riitta Luoto & Timo Partonen. (2012) Further evidence for lack of negative associations between hormonal contraception and mental health. Contraception 86:5, pages 470-480.
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E. Toffol, O. Heikinheimo, P. Koponen, R. Luoto & T. Partonen. (2011) Hormonal contraception and mental health: results of a population-based study. Human Reproduction 26:11, pages 3085-3093.
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Deeptej Singh. 2011. Acne Vulgaris. Acne Vulgaris 166 176 .
Deeptej Singh, Alan R. Shalita & Guy F. Webster. 2011. Acne Vulgaris. Acne Vulgaris 166 176 .

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