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Platelets Volume 13, 2002 - Issue 1
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Research Article

Aggregation of human platelets by gingipain-R from Porphyromonas gingivalis cells and membrane vesicles

K. Pham Department of Restorative Dentistry, Temple University School of Dentistry, 3223 N. Broad St., Philadelphia, Pa. 19128, USA.
,
D. Feik Department of Restorative Dentistry, Temple University School of Dentistry, 3223 N. Broad St., Philadelphia, Pa. 19128, USA.
,
B.F. Hammond Department of Restorative Dentistry, Temple University School of Dentistry, 3223 N. Broad St., Philadelphia, Pa. 19128, USA.
,
T.E. Rams Department of Restorative Dentistry, Temple University School of Dentistry, 3223 N. Broad St., Philadelphia, Pa. 19128, USA.
&
E.J. Whitaker Department of Restorative Dentistry, Temple University School of Dentistry, 3223 N. Broad St., Philadelphia, Pa. 19128, USA.
Pages 21-30 | Published online: 07 Jul 2009

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Toru Kariu, Tsuyoshi Ikeda, Keisuke Nakashima, Jan Potempa & Takahisa Imamura. (2019) A natural anti-periodontitis agent, epimedokoreanin B, inhibits virulence activities of gingipains from Porphyromonas gingivalis. Bioscience, Biotechnology, and Biochemistry 83:7, pages 1382-1384.
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Oonagh Shannon. (2015) Platelet interaction with bacterial toxins and secreted products. Platelets 26:4, pages 302-308.
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Steven W. Kerrigan & Dermot Cox. (2009) The thrombotic potential of oral pathogens. Journal of Oral Microbiology 1:1.
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Amber Watts, Eileen M Crimmins & Margaret Gatz. (2008) Inflammation as a potential mediator for the association between periodontal disease and Alzheimer’s disease. Neuropsychiatric Disease and Treatment 4:5, pages 865-876.
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M. Nylander, T. L. Lindahl, T. Bengtsson & M. Grenegård. (2008) The periodontal pathogen sensitises human blood platelets to epinephrine. Platelets 19:5, pages 352-358.
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Articles from other publishers (29)

Toru Kariu, Nobushiro Hamada & Kesavalu Lakshmyya. (2023) Luteolin inhibits Porphyromonas gingivalis growth and alleviates alveolar bone destruction in experimental murine periodontitis . Bioscience, Biotechnology, and Biochemistry.
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Diego F. Gualtero, Gloria Inés Lafaurie, Diana Marcela Buitrago, Yormaris Castillo, Paula Katherine Vargas-Sanchez & Diana Marcela Castillo. (2023) Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review. Frontiers in Cardiovascular Medicine 10.
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Martin J. Page & Etheresia Pretorius. (2021) Platelet Behavior Contributes to Neuropathologies: A Focus on Alzheimer's and Parkinson's Disease. Seminars in Thrombosis and Hemostasis 48:03, pages 382-404.
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EugeneJ Whitaker, CaitlinD Darcey & SusanM Somerset. (2022) Aggregation of human platelets by Tannerella Forsythia. Contemporary Clinical Dentistry 13:2, pages 135.
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D. S. Shlykova, V. M. Pisarev, A. M. Gaponov & A. V. Tutelyan. (2021) Interaction of bacterial extracellular microvesicles with eukaryotic cells.. Medical Immunology (Russia) 22:6, pages 1065-1084.
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William A. Chen, Hansel M. Fletcher, Joseph D. Gheorghe, Udochukwu Oyoyo & Danilo S. Boskovic. (2020) Platelet plug formation in whole blood is enhanced in the presence of Porphyromonas gingivalis . Molecular Oral Microbiology 35:6, pages 251-259.
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Martin J. Page & Etheresia Pretorius. (2020) A Champion of Host Defense: A Generic Large-Scale Cause for Platelet Dysfunction and Depletion in Infection. Seminars in Thrombosis and Hemostasis 46:03, pages 302-319.
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Priscila Cunha Nascimento, Micaele Maria Lopes Castro, Marcela Baraúna Magno, Anna Paula Costa Ponte Sousa Carvalho Almeida, Nathália Carolina Fernandes Fagundes, Lucianne Cople Maia & Rafael Rodrigues Lima. (2019) Association Between Periodontitis and Cognitive Impairment in Adults: A Systematic Review. Frontiers in Neurology 10.
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Yvonne Jockel‐Schneider, Anne Kobsar, Angelika Stellzig‐Eisenhauer, Ulrich Vogel, Stefan Störk, Stefan Frantz, Ulrich Schlagenhauf & Martin Eigenthaler. (2018) Wild‐type isolates of Porphyromonas gingivalis derived from periodontitis patients display major variability in platelet activation . Journal of Clinical Periodontology 45:6, pages 693-700.
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Lobna A. Aly, Hala El-Menoufy, Rehab Tarek Elsharkawy, Mona Z. Zaghloul & Dina Sabry. (2015) Maternal chronic oral infection with periodontitis and pericoronitis as a possible risk factor for preeclampsia in Egyptian pregnant women (microbiological and serological study). Future Dental Journal 1:1, pages 23-32.
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Ingrida Marija Pacauskienė, Eglė Stasiukonė & Benita Vaišvilaitė. (2015) Preeklampsijos ir lėtinio periodontito ryšys. Sveikatos mokslai 25:3, pages 101-106.
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Richa Priyadarshini, Carla Cugini, Annette Arndt, Tsute Chen, Natalia O. Tjokro, Steven D. Goodman & Mary E. Davey. (2013) The nucleoid-associated protein HUβ affects global gene expression in Porphyromonas gingivalis. Microbiology 159:Pt_2, pages 219-229.
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P. Swati, Betsy Thomas, Saadi Abdul Vahab, Satyamoorthy Kapaettu & Pralhad Kushtagi. (2011) Simultaneous detection of periodontal pathogens in subgingival plaque and placenta of women with hypertension in pregnancy. Archives of Gynecology and Obstetrics 285:3, pages 613-619.
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Jing Xiong, Virginia M. Miller, Yunman Li & Muthuvel Jayachandran. (2012) Microvesicles at the Crossroads Between Infection and Cardiovascular Diseases. Journal of Cardiovascular Pharmacology 59:2, pages 124-132.
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Mary Ellen Davey, Heike Boisvert & Annette Arndt. 2011. Oral Microbial Communities. Oral Microbial Communities 119 134 .
Kang-min Yu, Yoshinori Inoue, Makoto Umeda, Hiroaki Terasaki, Zhi-yong Chen & Takehisa Iwai. (2011) The peridontal anaerobe Porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model. Thrombosis Research 127:5, pages 418-425.
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Emma Börgeson, Johanna Lönn, Ida Bergström, Veronika Patcha Brodin, Sofia Ramström, Fariba Nayeri, Eva Särndahl & Torbjörn Bengtsson. (2011) Lipoxin A 4 Inhibits Porphyromonas gingivalis -Induced Aggregation and Reactive Oxygen Species Production by Modulating Neutrophil-Platelet Interaction and CD11b Expression . Infection and Immunity 79:4, pages 1489-1497.
Crossref
Yonghua Guo, Ky-Anh Nguyen & Jan Potempa. (2010) Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon’s knife to a meat chopper-like brutal degradation of proteins. Periodontology 2000 54:1, pages 15-44.
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Archibald McNicolSara J. Israels. (2010) Mechanisms of oral bacteria-induced platelet activation. Canadian Journal of Physiology and Pharmacology 88:5, pages 510-524.
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Lea M. Beaulieu & Jane E. Freedman. (2010) The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes. Thrombosis Research 125:3, pages 205-209.
Crossref
Steven Kerrigan & Dermot Cox. 2011. Toxins and Hemostasis. Toxins and Hemostasis 637 651 .
Annette Arndt & Mary Ellen Davey. 2010. Interface Oral Health Science 2009. Interface Oral Health Science 2009 382 387 .
Nobumichi Furuta, Hiroki Takeuchi & Atsuo Amano. (2009) Entry of Porphyromonas gingivalis Outer Membrane Vesicles into Epithelial Cells Causes Cellular Functional Impairment . Infection and Immunity 77:11, pages 4761-4770.
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Nobumichi Furuta, Kayoko Tsuda, Hiroko Omori, Tamotsu Yoshimori, Fuminobu Yoshimura & Atsuo Amano. (2009) Porphyromonas gingivalis Outer Membrane Vesicles Enter Human Epithelial Cells via an Endocytic Pathway and Are Sorted to Lysosomal Compartments . Infection and Immunity 77:10, pages 4187-4196.
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T. Bengtsson, H. Karlsson, P. Gunnarsson, C. Skoglund, C. Elison, P. Leanderson & M. Lindahl. (2008) The periodontal pathogen Porphyromonas gingivalis cleaves apoB-100 and increases the expression of apoM in LDL in whole blood leading to cell proliferation. Journal of Internal Medicine 263:5, pages 558-571.
Crossref
P. JÄREMO, C. STARKHAMMAR, Å. LUNDSTRÖM, T.L. LINDAHL & A. RICHTER. (2007) Inverse relationship between the severity of gingivitis and platelet reactivity in stable angina pectoris. Journal of Thrombosis and Haemostasis 5:2, pages 422-423.
Crossref
A. Contreras, J.A. Herrera, J.E. Soto, R.M. Arce, A. Jaramillo & J.E. Botero. (2006) Periodontitis Is Associated With Preeclampsia in Pregnant Women. Journal of Periodontology 77:2, pages 182-188.
Crossref
Frank C. Gibson & Caroline Attardo Genco. 2006. The Prokaryotes. The Prokaryotes 428 454 .
Nadine BrodalaElizabeth P. MerricksDwight A. BellingerDamrong DamrongsriSteven OffenbacherJames BeckPhoebus MadianosDaniela SotresYu-Ling ChangGary KochTimothy C. Nichols. (2005) Porphyromonas gingivalis Bacteremia Induces Coronary and Aortic Atherosclerosis in Normocholesterolemic and Hypercholesterolemic Pigs . Arteriosclerosis, Thrombosis, and Vascular Biology 25:7, pages 1446-1451.
Crossref

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