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Original Article

Clopidogrel (Plavix®) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding

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Pages 325-332 | Published online: 07 Jul 2009

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Read on this site (4)

Dejana Bogdanić, Nikolina Bogdanić & Nenad Karanović. (2020) Evaluation of platelet count and platelet function analyzer – 100 testing for prediction of platelet transfusion following coronary bypass surgery. Scandinavian Journal of Clinical and Laboratory Investigation 80:4, pages 296-302.
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Pär I. Johansson, Sacha Sølbeck, Gustav Genet, Jakob Stensballe & Sisse R. Ostrowski. (2012) Coagulopathy and hemostatic monitoring in cardiac surgery: An update. Scandinavian Cardiovascular Journal 46:4, pages 194-202.
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G. Scharbert, A. Auer & S. Kozek-Langenecker. (2009) Evaluation of the Platelet Mapping™ Assay on rotational thromboelastometry ROTEM®. Platelets 20:2, pages 125-130.
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A. R. Hobson, R. A. Agarwala, R. A. Swallow, K. D. Dawkins & N. P. Curzen$suffix/text()$suffix/text(). (2006) Thrombelastography: Current clinical applications and its potential role in interventional cardiology. Platelets 17:8, pages 509-518.
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Articles from other publishers (39)

Hani Shamseddeen, Kavish R. Patidar, Marwan Ghabril, Archita P. Desai, Lauren Nephew, Sandra Kuehl, Naga Chalasani & Eric S. Orman. (2020) Features of Blood Clotting on Thromboelastography in Hospitalized Patients With Cirrhosis. The American Journal of Medicine 133:12, pages 1479-1487.e2.
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Marco Ranucci & Ekaterina Baryshnikova. (2020) Sensitivity of Viscoelastic Tests to Platelet Function. Journal of Clinical Medicine 9:1, pages 189.
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Yehuda Raveh, Gaetano Ciancio, George W. Burke, Jose Figueiro, Linda Chen, Mahmoud Morsi, Nicholas Namias, Bhavna P. Singh, Martine Lindsay, Waseem Alfahel, Mahmoud S. Sleem & Ramona Nicolau‐Raducu. (2019) Susceptibility‐directed anticoagulation after pancreas transplantation: A single‐center retrospective study. Clinical Transplantation 33:7.
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Brittney Williams, John McNeil, Andrew Crabbe & Kenichi A. Tanaka. (2017) Practical Use of Thromboelastometry in the Management of Perioperative Coagulopathy and Bleeding. Transfusion Medicine Reviews 31:1, pages 11-25.
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Cindy J. Wang. 2017. You’re Wrong, I’m Right. You’re Wrong, I’m Right 75 78 .
D. Bolliger & K.A. Tanaka. (2016) Fibrinogen—is it a universal haemostatic agent?. British Journal of Anaesthesia 117:5, pages 548-550.
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S. Agarwal. (2016) Platelet function testing in cardiac surgery. Transfusion Medicine 26:5, pages 319-329.
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M. Muñoz, S. Gómez‐Ramírez & S. Kozek‐Langeneker. (2015) Pre‐operative haematological assessment in patients scheduled for major surgery. Anaesthesia 71:S1, pages 19-28.
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Jerrold H. Levy. 2016. Trauma Induced Coagulopathy. Trauma Induced Coagulopathy 529 542 .
Seema Agarwal, Robert Ian Johnson & Matthew Shaw. (2015) Preoperative Point-of-Care Platelet Function Testing in Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia 29:2, pages 333-341.
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Kerry J. Welsh, Angelica Padilla, Amitava Dasgupta, Andy N. D. Nguyen & Amer Wahed. (2014) Thromboelastography Is a Suboptimal Test for Determination of the Underlying Cause of Bleeding Associated With Cardiopulmonary Bypass and May Not Predict a Hypercoagulable State. American Journal of Clinical Pathology 142:4, pages 492-497.
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Andreas Koster, Jochen Börgermann, Jan Gummert, Markus Rudloff, Armin Zittermann & Uwe Schirmer. (2013) Protamine Overdose and Its Impact on Coagulation, Bleeding, and Transfusions After Cardiopulmonary Bypass. Clinical and Applied Thrombosis/Hemostasis 20:3, pages 290-295.
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John McNeil & Adam B. Lerner. (2013) Standard Thromboelastography Should Not Be Used to Assess Candidacy for Neuraxial Procedures in Patients Taking P2Y12 Inhibitors. Anesthesiology 119:4, pages 993-993.
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Michael Mazzeffi, Fania Szlam, Joseph A. Jakubowski, Kenichi A. Tanaka, Atsuhiro Sugidachi & Jerrold H. Levy. (2013) In vitro effects of recombinant activated factor VII on thrombin generation and coagulation following inhibition of platelet procoagulant activity by prasugrel. Thrombosis Research 132:1, pages 106-111.
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Petra Seeber & Aryeh Shander. 2012. Basics of Blood Management. Basics of Blood Management 139 159 .
Kenichi A. Tanaka, Satoru Ogawa & Daniel Bolliger. (2012) A Primer for Clinical Use of Rotational Thromboelastometry. Point of Care: The Journal of Near-Patient Testing & Technology 11:2, pages 77-84.
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Sibylle A. Kozek‐Langenecker & Eva Schaden. 2010. Alternatives to Blood Transfusion in Transfusion Medicine. Alternatives to Blood Transfusion in Transfusion Medicine 253 266 .
Jerrold H Levy & Marc Azran. (2010) Anesthetic concerns for patients with coagulopathy. Current Opinion in Anaesthesiology 23:3, pages 400-405.
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Sibylle A. Kozek-Langenecker. (2010) Perioperative coagulation monitoring. Best Practice & Research Clinical Anaesthesiology 24:1, pages 27-40.
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Satoru OGAWA, Jun KAWASAKI & Kenichi TANAKA. (2010) Management of Perioperative Hemostasis using Thromboelastometry. Japanese Journal of Thrombosis and Hemostasis 21:6, pages 553-561.
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Mei-Yung Tsou. (2009) Evaluation of the Platelet Function Analyzer (PFA-100®) vs. the Thromboelastogram (TEG®) in the Clinical Setting. Acta Anaesthesiologica Taiwanica 47:3, pages 107-109.
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Mark C. Wesley, Francis X. McGowan, Robert A. Castro, Sheahan Dissanayake, David Zurakowski & James A. DiNardo. (2009) The Effect of Milrinone on Platelet Activation as Determined by TEG® Platelet Mapping™. Anesthesia & Analgesia 108:5, pages 1425-1429.
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N. M. Gibbs. (2009) Point-of-Care Assessment of Antiplatelet Agents in the Perioperative Period: A Review. Anaesthesia and Intensive Care 37:3, pages 354-369.
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Gregory A. Nuttall. 2009. Evidence-Based Practice of Anesthesiology. Evidence-Based Practice of Anesthesiology 163 168 .
Yangyang Zhang & Kejiang Cao. (2008) The clinical application of clopidogrel in current coronary artery surgery. Journal of Nanjing Medical University 22:6, pages 329-334.
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K J Dickinson, M Troxler & S Homer-Vanniasinkam. (2008) The surgical application of point-of-care haemostasis and platelet function testing. British Journal of Surgery 95:11, pages 1317-1330.
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S. Müller-Schunk, J. Linn, N. Peters, M. Spannagl, M. Deisenberg, H. Brückmann & T.E. Mayer. (2008) Monitoring of Clopidogrel-Related Platelet Inhibition: Correlation of Nonresponse with Clinical Outcome in Supra-Aortic Stenting. American Journal of Neuroradiology 29:4, pages 786-791.
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Helfried Metzler, Sibylle Kozek-Langenecker & Kurt Huber. (2008) Antiplatelet therapy and coronary stents in perioperative medicine – the two sides of the coin. Best Practice & Research Clinical Anaesthesiology 22:1, pages 81-94.
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Yao-Zu Xiang, Li-Yuan Kang, Xiu-Mei Gao, Hong-Cai Shang, Jun-Hua Zhang & Bo-Li Zhang. (2008) Strategies for antiplatelet targets and agents. Thrombosis Research 123:1, pages 35-49.
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Andreas Calatzis. (2007) Vollblutverfahren zur Erfassung der primären Hämostase / Analysis of primary hemostasis in whole blood. LaboratoriumsMedizin 31:6, pages 239-247.
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Marco Ranucci, Giovanni Nano, Alfredo Pazzaglia, Paolo Bianchi, Renato Casana & Domenico G. Tealdi. (2007) Platelet Mapping and Desmopressin Reversal of Platelet Inhibition During Emergency Carotid Endarterectomy. Journal of Cardiothoracic and Vascular Anesthesia 21:6, pages 851-854.
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J. Kawasaki, N. Katori, T. Taketomi, K. Terui & K. A. Tanaka. (2007) The effects of vasoactive agents, platelet agonists and anticoagulation on thrombelastography. Acta Anaesthesiologica Scandinavica 51:9, pages 1237-1244.
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Jerrold H. Levy & Kenichi A. Tanaka. (2007) The anticoagulated patient: Strategies for effective blood loss management. Surgery 142:4, pages S71-S77.
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Petra Seeber & Aryeh Shander. 2007. Basics of Blood Management. Basics of Blood Management 139 159 .
G.M. Howard-Alpe, J. de Bono, L. Hudsmith, W.P. Orr, P. Foex & J.W. Sear. (2007) Coronary artery stents and non-cardiac surgery. British Journal of Anaesthesia 98:5, pages 560-574.
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H. Metzler, K. Huber, S. Kozek-Langenecker, M.N. Vicenzi & A. Münch. (2007) Koronare Stents, duale Antiplättchentherapie und die perioperative ProblematikCoronary stents, dual antiplatelet therapy and peri-operative problems. Der Anaesthesist 56:4, pages 401-412.
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Ulrica Alström, Hans Tydén, Jonas Oldgren, Agneta Siegbahn & Elisabeth Ståhle. (2007) The platelet inhibiting effect of a clopidogrel bolus dose in patients on long-term acetylsalicylic acid treatment. Thrombosis Research 120:3, pages 353-359.
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N. M. Gibbs, D. Yim, W. Weightman, M. Sheminant & R. Rowe. (2019) The Effect of Excess Protamine on Thrombelastography in Vitro. Anaesthesia and Intensive Care 34:5, pages 579-585.
Crossref
Jan van der LindenGabriella LindvallUlrik Sartipy. (2005) Aprotinin Decreases Postoperative Bleeding and Number of Transfusions in Patients on Clopidogrel Undergoing Coronary Artery Bypass Graft Surgery. Circulation 112:9_supplement.
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