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Platelets Volume 16, 2005 - Issue 7
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Original Article

Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism

Adam R. Hardy Department of Pharmacology, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
,
Darryl J. Hill Department of Pathology & Microbiology, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
&
Alastair W. Poole Department of Pharmacology, School of Medical Sciences, University Walk, Bristol BS8 1TD, UKCorrespondence[email protected]
Pages 415-429 | Received 12 Jan 2005, Accepted 14 Feb 2005, Published online: 07 Jul 2009

Citations (13)

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Kjersti Tunströmer, Lars Faxälv, Pia Larsson, Tomas L. Lindahl & Niklas Boknäs. (2023) Thrombus remodelling by reversible and irreversible P2Y12 inhibitors. Platelets 34:1.
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Pei-Wen Liu, Ming-Xia Yue, Rui Zhou, Juan Niu, Du-Juan Huang, Tao Xu, Pei Luo, Xiao-Hong Liu & Jun-Wei Zeng. (2017) P2Y12 and P2Y13 receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia. Journal of Pain Research 10, pages 1755-1767.
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Articles from other publishers (11)

Rachit Badolia, Vaishali Inamdar, Bhanu Kanth Manne, Carol Dangelmaier, Johannes A. Eble & Satya P. Kunapuli. (2017) Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets. Journal of Biological Chemistry 292:35, pages 14516-14531.
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Yaqi Zhang, Si Zhang & Zhongren Ding. 2017. Thrombosis and Embolism: from Research to Clinical Practice. Thrombosis and Embolism: from Research to Clinical Practice 307 324 .
Geoffrey Burnstock. (2015) Blood cells: an historical account of the roles of purinergic signalling. Purinergic Signalling 11:4, pages 411-434.
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Emiko Tatsumi, Hiroki Yamanaka, Kimiko Kobayashi, Hideshi Yagi, Masafumi Sakagami & Koichi Noguchi. (2015) RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain. Glia 63:2, pages 216-228.
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Yaqi Zhang, Si Zhang & Zhongren Ding. 2015.
Margaret R. CunninghamShaista P. NisarStuart J. Mundell. (2013) Molecular mechanisms of platelet P2Y12 receptor regulation. Biochemical Society Transactions 41:1, pages 225-230.
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Brian M. SteeleMatthew T. HarperIain C. MacaulayCraig N. Morrell, Alita Perez-Tamayo, Martina FoyRaymond Habas, Alastair W. PooleDesmond J. FitzgeraldPatricia B. Maguire. (2009) Canonical Wnt signaling negatively regulates platelet function. Proceedings of the National Academy of Sciences 106:47, pages 19836-19841.
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Laszlo Köles, Zoltan Gerevich, João Felipe Oliveira, Zoltan Sandor Zadori, Kerstin Wirkner & Peter Illes. (2007) Interaction of P2 purinergic receptors with cellular macromolecules. Naunyn-Schmiedeberg's Archives of Pharmacology 377:1, pages 1-33.
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G.J. JOHNSON, L.A. LEIS, M.D. KRUMWIEDE & J.G. WHITE. (2007) The critical role of myosin IIA in platelet internal contraction. Journal of Thrombosis and Haemostasis 5:7, pages 1516-1529.
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Davide Ferrari, Stefania Gorini, Giulia Callegari & Andrea la Sala. (2006) Shaping immune responses through the activation of dendritic cells–P2 receptors. Purinergic Signalling 3:1-2.
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James K. T. WentworthGiordano PulaAlastair W. Poole. (2005) Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets. Biochemical Journal 393:2, pages 555-564.
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