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Research Article

Functional characterization of platelet ADP receptors

Pages 343-351 | Published online: 07 Jul 2009

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Ivan Budnik, Boris Shenkman, Hagit Hauschner, Isaac Zilinsky & Naphtali Savion. (2018) Role of heterotrimeric G proteins in platelet activation and clot formation in platelets treated with integrin αIIbβ3 inhibitor. Platelets 29:3, pages 265-269.
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Kjeld Christensen, Rolf Larsson, Håkan Emanuelsson, Graciela Elgue & Anders Larsson. (2006) Effects on blood compatibility by combining a direct P2Y12 receptor inhibitor and heparin coating of stents. Platelets 17:5, pages 318-327.
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Jacqueline R. Glenn, Ann E. White, Andrew Johnson, Susan C. Fox, Miles W.H. Behan, Gerry Dolan & Stanley Heptinstall. (2005) Leukocyte count and leukocyte ecto-nucleotidase are major determinants of the effects of adenosine triphosphate and adenosine diphosphate on platelet aggregation in human blood. Platelets 16:3-4, pages 159-170.
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I. Anita Jagroop, Miltiadis I. Matsagas, George Geroulakos & Dimitri P. Mikhailidis. (2004) The effect of clopidogrel, aspirin and both antiplatelet drugs on platelet function in patients with peripheral arterial disease. Platelets 15:2, pages 117-125.
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Benjamin Z.S. Paul, Soochong Kim, Carol Dangelmaier, Chandrasekaran Nagaswami, Jianguo Jin, John H. Hartwig, John W. Weisel, James L. Daniel & Satya P. Kunapuli. (2003) Dynamic regulation of microtubule coils in ADP-induced platelet shape change by p160ROCK (Rho-kinase). Platelets 14:3, pages 159-169.
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Articles from other publishers (22)

Donald J. AbrahamSamuel Chackalamannil. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 70 .
Juergen Koessler, Valerie-Noelle Trulley, Andrea Bosch, Katja Weber, Angela Koessler, Markus Boeck & Anna Kobsar. (2018) The role of agonist-induced activation and inhibition for the regulation of purinergic receptor expression in human platelets. Thrombosis Research 168, pages 40-46.
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Juergen Koessler, Michaela Schwarz, Katja Weber, Julia Etzel, Angela Koessler, Markus Boeck & Anna Kobsar. (2017) The role of adenosine diphosphate mediated platelet responsiveness for the stability of platelet integrity in citrated whole blood under ex vivo conditions. PLOS ONE 12:11, pages e0188193.
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Juergen Koessler, Stephanie Hermann, Katja Weber, Angela Koessler, Sabine Kuhn, Markus Boeck & Anna Kobsar. (2016) Role of Purinergic Receptor Expression and Function for Reduced Responsiveness to Adenosine Diphosphate in Washed Human Platelets. PLOS ONE 11:1, pages e0147370.
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Geoffrey Burnstock. (2015) Blood cells: an historical account of the roles of purinergic signalling. Purinergic Signalling 11:4, pages 411-434.
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Katja A. Roscher, Klaus Failing & Andreas Moritz. (2015) Inhibition of platelet function with clopidogrel, as measured with a novel whole blood impedance aggregometer in horses. The Veterinary Journal 203:3, pages 332-336.
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David A. OsmondShali ZhangJennifer S. Pollock, Tatsuo Yamamoto, Carmen De Miguel & Edward W. Inscho. (2014) Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension. American Journal of Physiology-Renal Physiology 306:6, pages F619-F628.
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Donald J. AbrahamSamuel Chackalamannil. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 409 476 .
Margarete D. Bagatini, Caroline C. Martins, Vanessa Battisti, Roselia M. Spanevello, Diogo Gasparetto, Cintia S. Rosa, Jamile Fabrin Gonçalves, Maria Rosa C. Schetinger, Romualdo B. dos Santos & Vera Maria Morsch. (2008) Hydrolysis of adenine nucleotides in platelets from patients with acute myocardial infarction. Clinical Biochemistry 41:14-15, pages 1181-1185.
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S. HEPTINSTALL, A. JOHNSON, J.R. GLENN & A.E. WHITE. (2005) Adenine nucleotide metabolism in human blood – important roles for leukocytes and erythrocytes. Journal of Thrombosis and Haemostasis 3:10, pages 2331-2339.
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Paolo Lova, Francesca Campus, Rossana Lombardi, Marco Cattaneo, Fabiola Sinigaglia, Cesare Balduini & Mauro Torti. (2004) Contribution of Protease-activated Receptors 1 and 4 and Glycoprotein Ib-IX-V in the Gi-independent Activation of Platelet Rap1B by Thrombin. Journal of Biological Chemistry 279:24, pages 25299-25306.
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S.C Fox, M.W.H Behan & S Heptinstall. (2004) Inhibition of ADP-induced intracellular Ca2+ responses and platelet aggregation by the P2Y12 receptor antagonists AR-C69931MX and clopidogrel is enhanced by prostaglandin E1. Cell Calcium 35:1, pages 39-46.
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Nicholas P. StaffordAndrew E. PinkAnn E. WhiteJacqueline R. GlennStan Heptinstall. (2003) Mechanisms Involved in Adenosine Triphosphate–Induced Platelet Aggregation in Whole Blood. Arteriosclerosis, Thrombosis, and Vascular Biology 23:10, pages 1928-1933.
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Miltiadis Matsagas, I. Anita Jagroop, George Geroulakos & Dimitri P. Mikhailidis. (2016) The Effect of a Loading Dose (300 mg) of Clopidogrel on Platelet Function in Patients with Peripheral Arterial Disease. Clinical and Applied Thrombosis/Hemostasis 9:2, pages 115-120.
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Paolo Lova, Simona Paganini, Fabiola Sinigaglia, Cesare Balduini & Mauro Torti. (2002) A Gi-dependent Pathway Is Required for Activation of the Small GTPase Rap1B in Human Platelets. Journal of Biological Chemistry 277:14, pages 12009-12015.
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Jarmo T. Laitinen, Asko Uri, Gerda Raidaru & Riitta Miettinen. (2001) [ 35 S]GTPγS autoradiography reveals a wide distribution of G i/o ‐linked ADP receptors in the nervous system: close similarities with the platelet P2Y ADP receptor . Journal of Neurochemistry 77:2, pages 505-518.
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Atsuhiro Sugidachi, Fumitoshi Asai, Kenji Yoneda, Ryo Iwamura, Taketoshi Ogawa, Ken‐ichi Otsuguro & Hiroyuki Koike. (2009) Antiplatelet action of R‐99224, an active metabolite of a novel thienopyridine‐type G i ‐linked P2T antagonist, CS‐747 . British Journal of Pharmacology 132:1, pages 47-54.
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Robert F. Storey. (2001) Clinical experience with antithrombotic drugs acting on purine receptor pathways. Drug Development Research 52:1-2, pages 202-212.
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Robert F. Storey, Heather M. Sanderson, Ann E. White, Jane A. May, Kathryn E. Cameron & Stan Heptinstall. (2001) The central role of the P 2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity . British Journal of Haematology 110:4, pages 925-934.
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Atsuhiro Sugidachi, Fumitoshi Asai, Taketoshi Ogawa, Teruhiko Inoue & Hiroyuki Koike. (2009) The in vivo pharmacological profile of CS‐747, a novel antiplatelet agent with platelet ADP receptor antagonist properties . British Journal of Pharmacology 129:7, pages 1439-1446.
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Joanne M. Smallheer, Richard E. Olson & Ruth R. Wexler. 2000. 103 122 .
Leslie V Parise. (1999) Integrin ?IIb?3 signaling in platelet adhesion and aggregation. Current Opinion in Cell Biology 11:5, pages 597-601.
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