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Research Article

Free radical scavenging and skin penetration of troxerutin and vitamin derivatives

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Pages 133-141 | Published online: 12 Jul 2009

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Xu Ping, Jia Junqing, Jia Junfeng & Jiang Enjin. (2012) Radioprotective effects of troxerutin against gamma irradiation in mice liver. International Journal of Radiation Biology 88:8, pages 607-612.
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Ashfaq Ahmed Khan Malik, Waqas Ahmad, Farhan Younas, Haroon Badshah, Shatha Alharazy, Shafiq Ur Rehman, Muhammad Imran Naseer, Osama Yousef Muthaffar, Rehmatullah Achakzai & Ikram Ullah. (2023) Pretreatment with troxerutin protects/improves neurological deficits in a mouse model of traumatic brain injury. Heliyon 9:7, pages e18033.
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Jinyong Lee, Hyunjun Yoon, Youn Jung Lee, Tae-Yoon Kim, Gahee Bahn, Young-heon Kim, Jun-Man Lim, Sang-Wook Park, Young-Sook Song, Mi-Sun Kim & Bo Ram Beck. (2023) Drug–Target Interaction Deep Learning-Based Model Identifies the Flavonoid Troxerutin as a Candidate TRPV1 Antagonist. Applied Sciences 13:9, pages 5617.
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Bimal Prasad Jit, Subhaswaraj Pattnaik, Rakesh Arya, Rutumbara Dash, Saubhagya Subhadarsini Sahoo, Biswajita Pradhan, Prajna Paramita Bhuyan, Pradyota Kumar Behera, Mrutyunjay Jena, Ashok Sharma, Paban Kumar Agrawala & Rajendra Kumar Behera. (2022) Phytochemicals: A potential next generation agent for radioprotection. Phytomedicine 106, pages 154188.
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Wilbur Johnson, Ivan J. Boyer, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder & Bart Heldreth. (2022) Safety Assessment of Ethers and Esters of Ascorbic Acid as Used in Cosmetics. International Journal of Toxicology 41:2_suppl, pages 57S-75S.
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Cong Chen, Lin-Tong Yu, Bai-Ru Cheng, Jiang-Lin Xu, Yun Cai, Jia-Lin Jin, Ru-Li Feng, Long Xie, Xin-Yan Qu, Dong Li, Jing Liu, Yan Li, Xiao-Yun Cui, Jin-Jin Lu, Kun Zhou, Qian Lin & Jie Wan. (2022) Promising Therapeutic Candidate for Myocardial Ischemia/Reperfusion Injury: What Are the Possible Mechanisms and Roles of Phytochemicals?. Frontiers in Cardiovascular Medicine 8.
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Yaser Jafari-Khataylou, Seyyed Jamal Emami & Navideh Mirzakhani. (2021) Troxerutin attenuates inflammatory response in lipopolysaccharide-induced sepsis in mice. Research in Veterinary Science 135, pages 469-478.
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Nida Jamali-Raeufy, Sedighe Kardgar, Tourandokht Baluchnejadmojarad, Mehrdad Roghani & Mina Goudarzi. (2019) Troxerutin exerts neuroprotection against lipopolysaccharide (LPS) induced oxidative stress and neuroinflammation through targeting SIRT1/SIRT3 signaling pathway. Metabolic Brain Disease 34:5, pages 1505-1513.
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Gil-Im Mun, Seoyoung Kim, Eun Choi, Cha Soon Kim & Yun-Sil Lee. (2018) Pharmacology of natural radioprotectors. Archives of Pharmacal Research 41:11, pages 1033-1050.
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Moslem Najafi, Elham Noroozi, Aniseh Javadi & Reza Badalzadeh. (2018) Anti-arrhythmogenic and anti-inflammatory effects of troxerutin in ischemia/reperfusion injury of diabetic myocardium. Biomedicine & Pharmacotherapy 102, pages 385-391.
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Ariraman Subastri, Arumugam Suyavaran, Ezhuthupurakkal Preedia Babu, Subramaniyam Nithyananthan, Rajamani Barathidasan & Chinnasamy Thirunavukkarasu. (2018) Troxerutin with copper generates oxidative stress in cancer cells: Its possible chemotherapeutic mechanism against hepatocellular carcinoma. Journal of Cellular Physiology 233:3, pages 1775-1790.
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Yuerong Wang, Shuangshuang Wei, Lintao Chen, Jinli Pei, Hao Wu, Yechun Pei, Yibo Chen & Dayong Wang. (2017) Transcriptomic analysis of gene expression in mice treated with troxerutin. PLOS ONE 12:11, pages e0188261.
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Xuan Xin, Xiao-Feng Li, Xinglong Xiao, Yuqian Tang & Guanglei Zhao. (2017) Facile and Efficient Acylation of Bioflavonoids Using Whole-Cell Biocatalysts in Organic Solvents. ACS Sustainable Chemistry & Engineering 5:11, pages 10662-10672.
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A. Subastri, K. Harikrishna, M. Sureshkumar, Ghedeir M. Alshammari, B. Aristatile & C. Thirunavukkarasu. (2017) Effect of troxerutin on 2-aminoanthracene and DNA interaction and its anti-mutagenic property. Biomedicine & Pharmacotherapy 88, pages 325-334.
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A. Subastri, C.H. Ramamurthy, A. Suyavaran, P. Lokeswara Rao, E. Preedia Babu, K. Hari Krishna, M. Suresh Kumar & C. Thirunavukkarasu. (2015) Probing the interaction of troxerutin with transfer RNA by spectroscopic and molecular modeling. Journal of Photochemistry and Photobiology B: Biology 153, pages 137-144.
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Rajagopalan Geetha, Mutulur Krishnamoorthy Radika, Emayavaramban Priyadarshini, Krishnamurthy Bhavani & Carani Venkatraman Anuradha. (2015) Troxerutin reverses fibrotic changes in the myocardium of high-fat high-fructose diet-fed mice. Molecular and Cellular Biochemistry 407:1-2, pages 263-279.
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A. Subastri, C.H. Ramamurthy, A. Suyavaran, R. Mareeswaran, P. Lokeswara Rao, M. Harikrishna, M. Suresh Kumar, V. Sujatha & C. Thirunavukkarasu. (2015) Spectroscopic and molecular docking studies on the interaction of troxerutin with DNA. International Journal of Biological Macromolecules 78, pages 122-129.
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Zi-Feng Zhang, Qun Shan, Juan Zhuang, Yan-Qiu Zhang, Xin Wang, Shao-Hua Fan, Jun Lu, Dong-Mei Wu, Bin Hu & Yuan-Lin Zheng. (2015) Troxerutin inhibits 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47)-induced hepatocyte apoptosis by restoring proteasome function. Toxicology Letters 233:3, pages 246-257.
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Sathish Sampath & Balasubramanian Karundevi. (2014) Effect of troxerutin on insulin signaling molecules in the gastrocnemius muscle of high fat and sucrose-induced type-2 diabetic adult male rat. Molecular and Cellular Biochemistry 395:1-2, pages 11-27.
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Rajagopalan Geetha, Baskaran Yogalakshmi, S. Sreeja, K. Bhavani & Carani Venkatraman Anuradha. (2013) Troxerutin suppresses lipid abnormalities in the heart of high-fat–high-fructose diet-fed mice. Molecular and Cellular Biochemistry 387:1-2, pages 123-134.
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R. Vinothkumar, R. Vinoth Kumar, V. Karthikkumar, P. Viswanathan, J. Kabalimoorthy & N. Nalini. (2014) Oral supplementation with troxerutin (trihydroxyethylrutin), modulates lipid peroxidation and antioxidant status in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Environmental Toxicology and Pharmacology 37:1, pages 174-184.
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Chan-Min Liu, Jie-Qiong Ma & Yao Lou. (2010) Chronic administration of troxerutin protects mouse kidney against d-galactose-induced oxidative DNA damage. Food and Chemical Toxicology 48:10, pages 2809-2817.
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Alper Celik, Omer F. Ersoy, Namik Ozkan, Huseyin A. Kayaoglu, Fikret Ozugurlu, Ebru A. Cakir, Nese Lordlar & Suna Omeroglu. (2010) Comparison of the effects of troxerutin and heparinoid on flap necrosis. Journal of Plastic, Reconstructive & Aesthetic Surgery 63:5, pages 875-883.
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Jun Lu, Dong-mei Wu, Bin Hu, Wei Cheng, Yuan-lin Zheng, Zi-feng Zhang, Qin Ye, Shao-hua Fan, Qun Shan & Yong-jian Wang. (2010) Chronic administration of troxerutin protects mouse brain against d-galactose-induced impairment of cholinergic system. Neurobiology of Learning and Memory 93:2, pages 157-164.
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Amanda N. Carlson & Anne M. Kenny. (2007) Is Vitamin D Insufficiency Associated With Peripheral Neuropathy?. The Endocrinologist 17:6, pages 319-325.
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Xiu-Fang Wang, Lanfeng Dong, Yan Zhao, Marco Tomasetti, Kun Wu & Jiri Neuzil. (2006) Vitamin E analogues as anticancer agents: Lessons from studies with α-tocopheryl succinate. Molecular Nutrition & Food Research 50:8, pages 675-685.
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P.A. Grabnar, N. Zajc & J. Kristl. (2006) Improvement of ascorbyl palmitate stability in lipid nanoparticle dispersions for dermal use. Journal of Drug Delivery Science and Technology 16:6, pages 443-448.
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Dharmendra Kumar Maurya, Sreedevi Balakrishnan, Veena Prakash Salvi & Cherupally Krishnan Krishnan Nair. (2005) Protection of cellular DNA from γ-radiation-induced damages and enhancement in DNA repair by troxerutin. Molecular and Cellular Biochemistry 280:1-2, pages 57-68.
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Paul Valensi, Claude Le Devehat, Jean-Louis Richard, Cherifo Farez, Taraneh Khodabandehlou, Richard A. Rosenbloom & Carolyn LeFante. (2005) A multicenter, double-blind, safety study of QR-333 for the treatment of symptomatic diabetic peripheral neuropathy. Journal of Diabetes and its Complications 19:5, pages 247-253.
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Leo Salter, Tim Clifford, Nick Morley, David Gould, Sandra Campbell & Alison Curnow. (2004) The use of comet assay data with a simple reaction mechanism to evaluate the relative effectiveness of free radical scavenging by quercetin, epigallocatechin gallate and N-acetylcysteine in UV-irradiated MRC5 lung fibroblasts. Journal of Photochemistry and Photobiology B: Biology 75:1-2, pages 57-61.
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Dharmendra Kumar MAURYA, Veena Prakash SALVI & Cherupally Krishnan KRISHNAN NAIR. (2004) Radioprotection of Normal Tissues in Tumor-bearing Mice by Troxerutin. Journal of Radiation Research 45:2, pages 221-228.
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