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Original Article

Reduction of Intracellular Glutathione Content and Radiosensitivity

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Pages 155-165 | Received 15 Aug 1985, Accepted 16 Dec 1985, Published online: 03 Jul 2009

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Shubhankar Suman, Zubeda Khan, Mahtab Zarin, Sudhir Chandna & Rakesh Kumar Seth. (2015) Radioresistant Sf9 insect cells display efficient antioxidant defence against high dose γ-radiation. International Journal of Radiation Biology 91:9, pages 732-741.
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R. Sharma & R.K. Kale. (1993) Effect of Radiation on Glyoxalase I and Glyoxalase II Activities in Spleen and Liver of Mice. International Journal of Radiation Biology 63:2, pages 233-238.
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O. Vos & W.S.D. Roos-Verhey. (1988) Radioprotection by Glutathione Esters and Cysteamine in Normal and Glutathione-depleted Mammalian Cells. International Journal of Radiation Biology 53:2, pages 273-281.
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S.W. Dean. (1987) Some Aspects of Glutathione Metabolism in Ataxia-telangiectasia Fibroblasts. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 52:1, pages 43-48.
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Angela S. Bellamy, R.D.H. Whelan, R.B. Lock & Bridget T. Hill. (1987) Effects of Fractionated X-irradiation on Subsequent Response to Acute X-irradiation in Two Human Tumour Cell Lines in Vitro. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:4, pages 681-691.
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G.P. van der Schans, O. Vos, W.S.D. Roos-Verheij & P.H.M. Lohman. (1986) The Influence of Oxygen on the Induction of Radiation Damage in DNA in Mammalian Cells after Sensitization by Intracellular Glutathione Depletion. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 50:3, pages 453-465.
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Articles from other publishers (16)

Yusuke Matsuya, Tatsuhiko Sato, Rui Nakamura, Shingo Naijo & Hiroyuki Date. (2020) A theoretical cell-killing model to evaluate oxygen enhancement ratios at DNA damage and cell survival endpoints in radiation therapy. Physics in Medicine & Biology 65:9, pages 095006.
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Beatrice Alexandra Golomb. (2018) Diplomats' Mystery Illness and Pulsed Radiofrequency/Microwave Radiation. Neural Computation 30:11, pages 2882-2985.
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Timothy A. Chan, Boris Hristov & Simon N. Powell. 2017. Clinical Radiation Oncology. Clinical Radiation Oncology 15 61 .
M. Langenbacher, R.J. Abdel-Jalil, W. Voelter, M. Weinmann & S.M. Huber. (2013) In vitro hypoxic cytotoxicity and hypoxic radiosensitizationHypoxische Zytotoxizität und Strahlensensibilisierung in vitro. Strahlentherapie und Onkologie 189:3, pages 246-255.
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David J. Carlson, Robert D. Stewart & Vladimir A. Semenenko. (2006) Effects of oxygen on intrinsic radiation sensitivity: A test of the relationship between aerobic and hypoxic linear-quadratic (LQ) model parametersa). Medical Physics 33:9, pages 3105-3115.
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Ganesh C. Jagetia, Narsipura G. Ganapathi, Ponemone Venkatesh, Nageshwar Rao & Manjeshwar S. Baliga. (2006) Evaluation of the radioprotective effect of Liv 52 in mice. Environmental and Molecular Mutagenesis 47:7, pages 490-502.
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Alba Hernández, Noel Xamena, Sara Gutiérrez, Antonia Velázquez, Amadeu Creus, Jordi Surrallés, Pere Galofré & Ricardo Marcos. (2006) Basal and induced micronucleus frequencies in human lymphocytes with different GST and NAT2 genetic backgrounds. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 606:1-2, pages 12-20.
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Hilmar M. Warenius, Rosalind White, John H. Peacock, John Hanson, Richard A. Britten & David Murray. (2000) The Influence of Hypoxia on the Relative Sensitivity of Human Tumor Cells to 62.5 MeV (p→Be) Fast Neutrons and 4 MeV Photons. Radiation Research 154:1, pages 54-63.
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M. Frankenberg-Schwager. 1993. Biological Effects and Physics of Solar and Galactic Cosmic Radiation. Biological Effects and Physics of Solar and Galactic Cosmic Radiation 1 31 .
E.C. Halperin, D.M. Brizel, G. Honore, M.R. Sontag, O.W. Griffith, D.D. Bigner & H.S. Friedman. (1992) The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine. International Journal of Radiation Oncology*Biology*Physics 24:1, pages 103-109.
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Edward A. Bump, Ramsey Al-Sarraf, Susan M. Pierce & C.Norman Coleman. (1992) Elevation of mouse kidney thiol content following administration of glutathione. Radiotherapy and Oncology 23:1, pages 21-25.
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M.P. Cornago, M.C. Lopez Zumel, M.V. Alvarez & M.C. Izquierdo. (1990) Glyoxylic compounds as radiosensitizers of hypoxic cells. Biochemical Medicine and Metabolic Biology 43:3, pages 253-262.
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Marlis Frankenberg-Schwager. (1989) Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation. Radiotherapy and Oncology 14:4, pages 307-320.
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Marvin B. Cohen & Douglas L. Duvel. (1988) Characterization of the inhibition of glutathione reductase and the recovery of enzyme activity in exponentially growing murine leukemia (11210) cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea. Biochemical Pharmacology 37:17, pages 3317-3320.
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O. Vos & W.S.D. Roos-Verhey. (1988) Endogenous versus exogenous thiols in radioprotection. Pharmacology & Therapeutics 39:1-3, pages 169-177.
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Michael A. Lea & Lawrence Panasci. (1987) Effects of carbamoylating agents on tumor metabolism. Critical Reviews in Oncology/Hematology 7:4, pages 329-371.
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