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Original Article

Initial Damage or Repair as the Major Determinant of Cellular Radiosensitivity?

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Pages 543-547 | Published online: 03 Jul 2009

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N. FORAY. (1996) Dose-rate effect on radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line. International Journal of Radiation Biology 69:2, pages 241-249.
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M.G.A. Alsbeih, B. Fertil, C. Badie & E.P. Malaise. (1995) The β Component of Human Cell Survival Curves and Its Relationship with Split-dose Recovery. International Journal of Radiation Biology 67:4, pages 453-460.
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G.P. Raaphorst, A. Bussey, M. Thakar, T. Bichay & C.E. Ng. (1993) Postirradiation Exposure to Hypotonic Saline Shows Normal Damage Processing in Radiation-sensitive Cell Lines. International Journal of Radiation Biology 64:5, pages 593-600.
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C. Baumstark-Khan. (1993) X-ray-induced DNA Double-strand Breaks as Lethal Lesions in Diploid Human Fibroblasts Compared to Chinese Hamster Ovary Cells. International Journal of Radiation Biology 63:3, pages 305-311.
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M.D. Story, K.C. Garrett, P.J. Tofilon & R.E. Meyn. (1993) Influence of Irradiation Conditions on the Measurement of DNA Double-strand Breaks by Pulsed-field Gel Electrophoresis. International Journal of Radiation Biology 63:3, pages 297-304.
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J.H. Peacock, J.J. Eady, S.M. Edwards, T.J. McMillan & G.G. Steel. (1992) The Intrinsic α/β Ratio for Human Tumour Cells: Is It a Constant?. International Journal of Radiation Biology 61:4, pages 479-487.
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G. Gordon Steel, T.J. McMillan & J.H. Peacock. (1989) The 5Rs of Radiobiology. International Journal of Radiation Biology 56:6, pages 1045-1048.
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E.R. Gatfield, D.J. Noble, G.C. Barnett, N.Y. Early, A.C.F. Hoole, N.F. Kirkby, S.J. Jefferies & N.G. Burnet. (2018) Tumour Volume and Dose Influence Outcome after Surgery and High-dose Photon Radiotherapy for Chordoma and Chondrosarcoma of the Skull Base and Spine. Clinical Oncology 30:4, pages 243-253.
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Pedro Carlos Lara, Jesús Joaquín López-Peñalver, Virgínea de Araújo Farias, M. Carmen Ruiz-Ruiz, Francisco Javier Oliver & José Mariano Ruiz de Almodóvar. (2015) Direct and bystander radiation effects: A biophysical model and clinical perspectives. Cancer Letters 356:1, pages 5-16.
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Ping Li, Li-bin Zhou, Xiao-dong Jin, Jing He, Zhong-ying Dai, Guang-ming Zhou, Qing-xiang Gao, Sha Li & Qiang Li. (2008) Assessment of DNA damage of Lewis lung carcinoma cells irradiated by carbon ions and X-rays using alkaline comet assay. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 266:2, pages 262-266.
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Seiichi WADA, Tran Van KHOA, Yasuhiko KOBAYASHI, Tomoo FUNAYAMA, Kikumi OGIHARA, Shunji UENO & Nobuhiko ITO. (2005) Prediction of Cellular Radiosensitivity from DNA Damage Induced by .GAMMA.-Rays and Carbon Ion Irradiation in Canine Tumor Cells. Journal of Veterinary Medical Science 67:11, pages 1089-1095.
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Ekkehard Dikomey, Kerstin Borgmann, Ingo Brammer & Ulla Kasten-Pisula. (2003) Molecular mechanisms of individual radiosensitivity studied in normal diploid human fibroblasts. Toxicology 193:1-2, pages 125-135.
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Seiichi WADA, Hidemitsu KURAHAYASHI, Yasuhiko KOBAYASHI, Tomoo FUNAYAMA, Kazuo YAMAMOTO, Masahiro NATSUHORI & Nobuhiko ITO. (2003) The Relationship between Cellular Radiosensitivity and Radiation-Induced DNA Damage Measured by the Comet Assay. Journal of Veterinary Medical Science 65:4, pages 471-477.
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S Withoff, KL Glazenburg, ML van Veen, MMJ Kraak, GAP Hospers, S Störkel, EGE de Vries, J Wilschut & T Daemen. (2001) Replication-defective recombinant Semliki Forest virus encoding GM-CSF as a vector system for rapid and facile generation of autologous human tumor cell vaccines. Gene Therapy 8:20, pages 1515-1523.
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M. E. Price, V. J. McKelvey-Martin, T. Robson, D. G. Hirst & S. R. McKeown. (2000) Induction and Rejoining of DNA Double-Strand Breaks in Bladder Tumor Cells. Radiation Research 153:6, pages 788-794.
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Tetsuo Akimoto, Norio Mitsuhashi, Hiroko Matsumoto, Hideyuki Sakurai, Katsuya Maebayashi, Keiko Higuchi, Miwako Nozaki & Hideo Niibe. (1999) Potentially lethal damage repair and its inhibitory effect of caffeine in two yolk sac tumor cell lines with different radiosensitivities. Cancer Letters 147:1-2, pages 199-206.
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Kirsi Pekkola-Heino, Kristina Servomaa, Anne Kiuru & Reidar Grenman. (1998) Sublethal damage repair capacity in carcinoma cell lines with p53 mutations. Head & Neck 20:4, pages 298-303.
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N. Foray, C.F. Arlett & E.P. Malaise. (1997) Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: A closer look. Biochimie 79:9-10, pages 567-575.
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Mats Harms-Ringdahl, Pierluigi Nicotera & Ian R. Radford. (1996) Radiation induced apoptosis. Mutation Research/Reviews in Genetic Toxicology 366:2, pages 171-179.
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M.I. Núñez, T.J. McMillan, M.T. Valenzuela, J.M.Ruiz de Almodóvar & V. Pedraza. (1996) Relationship between DNA damage, rejoining and cell killing by radiation in mammalian cells. Radiotherapy and Oncology 39:2, pages 155-165.
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Elies C. Woudstra, Jeanette F. Brunsting, Judith M. Roesink, Antonius W.T. Konings & Harm H. Kampinga. (1996) Radiation induced DNA damage and damage repair in three human tumour cell lines. Mutation Research/DNA Repair 362:1, pages 51-59.
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Patrick J. Deschavanne & Bernard Fertil. (1996) A review of human cell radiosensitivity in vitro. International Journal of Radiation Oncology*Biology*Physics 34:1, pages 251-266.
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Ludwika Kreja, Christoph Selig, Ulla Plappert & Wilhelm Nothdurft. (1996) Radiation-induced DNA damage in canine hemopoietic cells and stromal cells as measured by the comet assay. Environmental and Molecular Mutagenesis 27:1, pages 39-45.
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N. Foray, C.F. Arlett & E.P. Malaise. (1995) Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia telangiectasia human fibroblast cell line. Biochimie 77:11, pages 900-905.
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N.G Burnet, J Nyman, I Turesson, R Wurm, J.R Yarnold & J.H Peacock. (1994) The relationship between cellular radiation sensitivity and tissue response may provide the basis for individualising radiotherapy schedules. Radiotherapy and Oncology 33:3, pages 228-238.
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Virpi Rantanen, Seija Gr�nman, Jarmo Kulmala, Kalle Alanen, Taina Lakkala & Reidar Gr�nman. (1994) Sublethal damage repair after fractionated irradiation in endometrial cancer cell lines tested with the 96-well plate clonogenic assay. Journal of Cancer Research and Clinical Oncology 120:12, pages 712-716.
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Reinhard Wurm, Neil G. Burnet, Nisha Duggal, John R. Yarnold & John H. Peacock. (1994) Cellular radiosensitivity and dna damage in primary human fibroblasts. International Journal of Radiation Oncology*Biology*Physics 30:3, pages 625-633.
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Dennis P. Heller & G.Peter Raaphorst. (1994) The kinetics of cellular recovery in exponential and plateau growth phase human glioma cells following γ-irradiation. International Journal of Radiation Oncology*Biology*Physics 30:2, pages 383-390.
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Attanas LALLEV, Boyka ANACHKOVA & George RUSSEV. (2005) Effect of ionizing radiation and topoisomerase II inhibitors on DNA synthesis in mammalian cells. European Journal of Biochemistry 216:1, pages 177-181.
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Simon Powell, Stephen Whitaker, John Peacock & Tevor McMillan. (1993) Ataxia telangiectasia: An investigation of the repair defect in the cell line AT5BIVA by plasmid reconstitution. Mutation Research/DNA Repair 294:1, pages 9-20.
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Kirsi Pekkola‐Heino, Jarmo Kulmala & Reidar Grenman. (2006) Sublethal damage repair in squamous cell carcinoma cell lines. Head & Neck 14:3, pages 196-199.
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Judith A. Stitt, Jack F. Fowler, Bruce R. Thomadsen, Dolores A. Buchler, Bhudatt P. Paliwal & Timothy J. Kinsella. (1992) High dose rate intracavitary brachytherapy for carcinoma of the cervix: The madison system: I. Clinical and radiobiological considerations. International Journal of Radiation Oncology*Biology*Physics 24:2, pages 335-348.
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Fumihiro Oshita, Yasuhiro Fujiwara & Nagahiro Saijo. (1992) Radiation sensitivities in various anticancer-drug-resistant human lung cancer cell lines and mechanism of radiation cross-resistance in a cisplatin-resistant cell line. Journal of Cancer Research and Clinical Oncology 119:1, pages 28-34.
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G Gordon Steel. (1991) The ESTRO Breur lecture cellular sensitivity to low dose-rate irradiation focuses the problem of tumour radioresistance. Radiotherapy and Oncology 20:2, pages 71-83.
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Michael C. Elia, John G. DeLuca & Matthews O. Bradley. (1991) Significance and measurement of DNA double strand breaks in mammalian cells. Pharmacology & Therapeutics 51:3, pages 291-327.
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X. Yang, J.L. Darling, T.J. McMillan, J.H. Peacock & G.G. Steel. (1990) Radio sensitivity, recovery and dose-rate effect in three human glioma cell lines. Radiotherapy and Oncology 19:1, pages 49-56.
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