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International Journal of Radiation Biology Volume 56, 1989 - Issue 5
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Original Article

Manipulation of Radiobiological Hypoxia in a Human Melanoma Xenograft to Exploit the Bioreductive Cytotoxicity of RSU-1069

S. Cole MRC Radiobiology Unit, Chilton, Didcot, Oxon, OX11 0RD, U.K.
,
I.J. Stratford MRC Radiobiology Unit, Chilton, Didcot, Oxon, OX11 0RD, U.K.
&
G.E. Adams MRC Radiobiology Unit, Chilton, Didcot, Oxon, OX11 0RD, U.K.
Pages 587-591 | Published online: 03 Jul 2009

Citations (7)

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Read on this site (2)

H.S. Edwards, J.C.M. Bremner & I.J. Stratford. (1991) Induction of Tumour Hypoxia by FAA and TNF: Interaction with Bioreductive Drugs. International Journal of Radiation Biology 60:1-2, pages 373-377.
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H.S. Edwards, J.C.M. Bremner & I.J. Stratford. (1991) Induction of Hypoxia in the KHT Sarcoma by Tumour Necrosis Factor and Flavone Acetic Acid. International Journal of Radiation Biology 59:2, pages 419-432.
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Articles from other publishers (5)

Gerald E. Adams & Ian J. Stratford. (1994) Bioreductive drugs for cancer therapy: The search for tumor specificity. International Journal of Radiation Oncology*Biology*Physics 29:2, pages 231-238.
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Jane C. M. Bremner. (1993) Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference toin vivo methods of evaluation. Cancer and Metastasis Reviews 12:2, pages 177-193.
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William A. Denny & William R. Wilson. (1993) Bioreducible mustards: a paradigm for hypoxia-selective prodrugs of diffusible cytotoxins (HPDCs). Cancer and Metastasis Reviews 12:2, pages 135-151.
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Gerald E. Adams, Jane C.M. Bremner, Christopher J.R. Counsell, Ian J. Stratford, Charles Thomas & Pauline J. Wood. (1992) Magnetic resonance spectroscopy studies on experimental murine and human tumors: Comparison of changes in phosphorus metabolism with induced changes in vascular volume. International Journal of Radiation Oncology*Biology*Physics 22:3, pages 467-471.
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G.E. Adams, I.J. Stratford, J.C.M. Bremner, S. Cole, H.S. Edwards & E.M. Fielden. (1991) Nitroheterocyclic compounds as radiation sensitizers and bioreductive drugs. Radiotherapy and Oncology 20, pages 85-91.
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