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Original Article

Linear Correlation between Surviving Fraction and the Micronucleus Frequency

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Pages 771-775 | Published online: 03 Jul 2009

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Read on this site (7)

M. Widel, Z. Kolosza, S. Jedruu, B. Lukaszczyk, K. Raczek-Zwierzycka & A. vwierniak. (2001) Micronucleus assay in vivo provides significant prognostic information in human cervical carcinoma; the updated analysis. International Journal of Radiation Biology 77:5, pages 631-636.
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M. JAMALI. (1996) Increased micronucleus frequency in the progeny of irradiated Chinese hamster cells. International Journal of Radiation Biology 69:3, pages 301-307.
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L.A. Jones, S. Clegg, C. Bush, T.J. McMillan & J.H. Peacock. (1994) Relationship between Chromosome Aberrations, Micronuclei and Cell Kill in Two Human Tumour Cell Lines of Widely Differing Radiosensitivity. International Journal of Radiation Biology 66:5, pages 639-642.
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A.C. Miller, J. Gafner, E.P. Clark & D. Samid. (1993) Differences in Radiation-induced Micronuclei Yields of Human Cells: Influence of Ras Gene Expression and Protein Localization. International Journal of Radiation Biology 64:5, pages 547-554.
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A. Vral, H. Thierens & L. de Ridder. (1992) Study of Dose-rate and Split-dose Effects on the in Vitro Micronucleus Yield in Human Lymphocytes Exposed to X-rays. International Journal of Radiation Biology 61:6, pages 777-784.
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Y. Shibamoto, C. Streffer, K. Sasai, N. Oya & M. Abe. (1992) Radiosensitization Efficacy of KU-2285, RP-170 and Etanidazole at Low Radiation Doses: Assessment by in Vitro Cytokinesis-block Micronucleus Assay. International Journal of Radiation Biology 61:4, pages 473-478.
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S. Masunaga, K. Ono, E.O. Wandl, M. Fushiki & M. Abe. (1990) Use of the Micronucleus Assay for the Selective Detection of Radiosensitivity in BUdR-unincorporated Cells after Pulse-labelling of Exponentially Growing Tumour Cells. International Journal of Radiation Biology 58:2, pages 303-311.
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Hee-Kyong Kim, Hyang-Hyun Cho & Hye-Ji Noh. (2016) In Vivo Evaluation of the Safety of Hydrolyzed GMP Powder containing Highly Concentrated Sialic Acid (23%) produced by Enzyme Separation and Solvent Enrichment Method using Micronucleus Test in Mice. Journal of Milk Science and Biotechnology 34:2, pages 83-89.
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Chandra Jagetia Ganesh & Venkatesh Ponemone. (2015) Bael, Aegle marmelos (L.) Correa, an Indian medicinal plant protects V79 cells against the genotoxic effect of doxorubicin. International Journal of Genetics and Molecular Biology 7:5, pages 32-46.
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Patrícia S. Guerreiro, Ana Sofia Fernandes, João G. Costa, Matilde Castro, Joana P. Miranda & Nuno G. Oliveira. (2013) Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxicity in MDA-MB-231 human breast cancer cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 757:2, pages 140-147.
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Yuichiro Yokota, Tomoo Funayama, Yoshihiro Hase, Nobuyuki Hamada, Yasuhiko Kobayashi, Atsushi Tanaka & Issay Narumi. (2010) Enhanced micronucleus formation in the descendants of γ-ray-irradiated tobacco cells: Evidence for radiation-induced genomic instability in plant cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 691:1-2, pages 41-46.
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Maria Konopacka & Joanna Rzeszowska-Wolny. (2006) The bystander effect-induced formation of micronucleated cells is inhibited by antioxidants, but the parallel induction of apoptosis and loss of viability are not affected. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 593:1-2, pages 32-38.
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Shalini Singh, Niloy R. Datta, Narendra Krishnani, Punita Lal & Shaleen Kumar. (2005) Radiation therapy induced micronuclei in cervical cancer—does it have a predictive value for local disease control?. Gynecologic Oncology 97:3, pages 764-771.
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Junji IWASHITA, Seiji KODAMA, Mikiro NAKASHIMA, Hitoshi SASAKI, Kotaro TANIYAMA & Masami WATANABE. (2005) Induction of Micronuclei in CHO Cells by Bleomycin but not by X-irradiation is Decreased by Treatment with HMG-CoA Reductase Inhibitors. Journal of Radiation Research 46:2, pages 191-195.
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A L Dunne, M E Price, C Mothersill, S R McKeown, T Robson & D G Hirst. (2003) Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells. British Journal of Cancer 89:12, pages 2277-2283.
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G.C Jagetia. (2002) Response to letter to the Editor. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 518:2, pages 227-228.
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Shin-ichiro Masunaga, Koji Ono, Minoru Suzuki, Yuko Kinashi & Masao Takagaki. (2001) Radiobiologic significance of apoptosis and micronucleation in quiescent cells within solid tumors following γ-ray irradiation. International Journal of Radiation Oncology*Biology*Physics 49:5, pages 1361-1368.
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Ganesh Chandra Jagetia & R. Aruna. (2000) Correlation between cell survival and micronuclei-induction in HeLa cells treated with adriamycin after exposure to various doses of γ-radiation. Toxicology Letters 115:3, pages 183-193.
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J. M. Akudugu, J. P. Slabbert, A. Serafin & L. Bohm. (2000) Frequency of Radiation-Induced Micronuclei in Neuronal Cells Does Not Correlate with Clonogenic Survival. Radiation Research 153:1, pages 62-67.
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Christos Kolotas, Carolin Tonus, Dimos Baltas, Marianne Cernea, Hans-Georg Vogt, Thomas Martin, Gerd Strassmann & Nikolaos Zamboglou. (2018) Clinical Relevance of Tumor Ploidy and Micronucleus Formation for Oral Cavity Cancer. Tumori Journal 85:4, pages 253-258.
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M Widel, S Jędruś, S Owczarek, M Konopacka, B Lubecka & Z Kolosza. (1999) The increment of micronucleus frequency in cervical carcinoma during irradiation in vivo and its prognostic value for tumour radiocurability. British Journal of Cancer 80:10, pages 1599-1607.
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Takehisa Takagi, Keisuke Sasai, Yuta Shibamoto, Kiyoshi Akagi, Natsuo Oya, Toru Shibata, Jeman Kim & Masahiro Hiraoka. (1998) The influence of DNA ploidy of a human tumor cell line on the frequencies of micronuclei or chromosome aberrations after irradiation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 418:1, pages 49-57.
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Ganesh Chandra Jagetia, Vijayashree Nayak & M.S Vidyasagar. (1998) Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in cultured HeLa cells. Cancer Letters 127:1-2, pages 71-82.
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Peter J Johnston, Elizabeth Stoppard & Peter E Bryant. (1997) Induction and distribution of damage in CHO-K1 and the X-ray-sensitive hamster cell line xrs5, measured by the cytochalasin-B-cytokinesis block micronucleus assay. Mutation Research/DNA Repair 385:1, pages 1-12.
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A.R. Champion, J.A. Hanson, S.E. Venables, A.D. McGregor & C.C. Gaffney. (1997) Determination of radiosensitivity in established and primary squamous cell carcinoma cultures using the micronucleus assay. European Journal of Cancer 33:3, pages 453-462.
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Carlo Catena, Luigi Asprea, Sergio Carta, Giuseppe Tortora, Daniela Conti, Patrizia Parasacchi & Enzo Righi. (1997) Dose-response of X-irradiated human and equine lymphocytes. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 373:1, pages 9-16.
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Kevin A. Hahn, Masoud Panjehpour & Xiaochen Lu. (2008) Fluence‐Dependent Induction of Micronuclei by Aluminum Phthalocyanine Tetrasulfonate‐Mediated Photodynamic Therapy. Photochemistry and Photobiology 63:1, pages 117-122.
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Adel Courdi, Danielle Mari, Serge Marcié, Jeannine Gioanni & Pierre Chauvel. (1995) Micronucleus induction in 10 human tumour cells after high- and low-dose radiation. Radiotherapy and Oncology 37:2, pages 117-123.
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Adel Courdi, Danielle Mari, Jo�l H�rault & Pierre Chauvel. (1995) Micronucleus induction and reproductive death in a human cell line exposed to low-energy argon beam. Radiation and Environmental Biophysics 34:2, pages 85-89.
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D.N. Floyd & A.M. Cassoni. (1994) Intrinsic radiosensitivity of adult and cord blood lymphocytes as determined by the micronucleus assay. European Journal of Cancer 30:5, pages 615-620.
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W.-U. Müller & C. Streffer. 1994. Advances in Mutagenesis Research. Advances in Mutagenesis Research 1 134 .
M Fenech. (1993) The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations.. Environmental Health Perspectives 101:suppl 3, pages 101-107.
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Michael Fenech. (1993) The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 285:1, pages 35-44.
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