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International Journal of Radiation Biology Volume 75, 1999 - Issue 12
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Research Article

Cytotoxicity of [ 125 I]iodoHoechst 33342: contribution of scavengeable effects

M.A. Walicka Department of Radiology, Harvard Medical School, Goldenson Building, 220 Longwood Avenue, Boston, MA 02115, USA.; On leave from the Institute of Nuclear Chemistry and Technology, Warsaw, Poland.
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Y. Ding Department of Radiology, Harvard Medical School, Goldenson Building, 220 Longwood Avenue, Boston, MA 02115, USA.
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A. M. Roy Department of Radiology, Harvard Medical School, Goldenson Building, 220 Longwood Avenue, Boston, MA 02115, USA.
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R. S. Harapanhalli Department of Radiology, Harvard Medical School, Goldenson Building, 220 Longwood Avenue, Boston, MA 02115, USA.
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S. J. Adelstein Department of Radiology, Harvard Medical School, Goldenson Building, 220 Longwood Avenue, Boston, MA 02115, USA.
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A. I. Kassis Department of Radiology, Harvard Medical School, Goldenson Building, 220 Longwood Avenue, Boston, MA 02115, USA.
Pages 1579-1587 | Published online: 03 Jul 2009

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Pavel Lobachevsky, George R. Clark, Patrycja D. Pytel, Brenda Leung, Colin Skene, Laura Andrau, Jonathan M. White, Tom Karagiannis, Carleen Cullinane, Boon Q. Lee, Andrew Stuchbery, Tibor Kibedi, Rodney J. Hicks & Roger F. Martin. (2016) Strand breakage by decay of DNA-bound 124I provides a basis for combined PET imaging and Auger endoradiotherapy. International Journal of Radiation Biology 92:11, pages 686-697.
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Pichumani Balagurumoorthy, Xiang Xu, Ketai Wang, S. James Adelstein & Amin I. Kassis. (2012) Effect of distance between decaying 125I and DNA on Auger-electron induced double-strand break yield. International Journal of Radiation Biology 88:12, pages 998-1008.
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Pavel Lobachevsky, Jai Smith, Delphine Denoyer, Colin Skene, Jonathan White, Bernard L. Flynn, Daniel J. Kerr, Rodney J. Hicks & Roger F. Martin. (2012) Tumour targeting of Auger emitters using DNA ligands conjugated to octreotate. International Journal of Radiation Biology 88:12, pages 1009-1018.
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Linda S. Yasui, Christine Andorf, Linda Schneider, Thomas Kroc, Arlene Lennox & K. R. Saroja. (2008) Gadolinium neutron capture in glioblastoma multiforme cells. International Journal of Radiation Biology 84:12, pages 1130-1139.
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Pavel N. Lobachevsky, Joanne White, Melissa Leung, Colin Skene, Jonathan White & Roger F. Martin. (2008) Plasmid breakage by 125I-labelled DNA ligands: Effect of DNA-iodine atom distance on breakage efficiency. International Journal of Radiation Biology 84:12, pages 991-1000.
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Amin I Kassis. (2005) Radiotargeting agents for cancer therapy. Expert Opinion on Drug Delivery 2:6, pages 981-991.
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Pavel N. Lobachevsky & Roger F. Martin. (2004) An Improved Approach to the Analysis of Plasmid DNA Breakage by Decay of DNA‐Associated Auger Emitters. International Journal of Radiation Biology 80:11-12, pages 861-866.
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Amin I. Kassis. (2004) The Amazing World of Auger Electrons. International Journal of Radiation Biology 80:11-12, pages 789-803.
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Tom C. Karagiannis, Pavel N. Lobachevsky, Roger F. Martin. (2000) Cytotoxicity of an 125I-Labelled DNA Ligand. Acta Oncologica 39:6, pages 681-685.
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Articles from other publishers (16)

Raymond C. Beh, Eleni Pitsillou, Julia J. Liang, Andrew Hung & Tom C. Karagiannis. (2022) In silico investigation of DNA minor groove binding bibenzimidazoles in the context of UV A phototherapy . Physical Chemistry Chemical Physics 24:1, pages 112-121.
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Gilnaz Omyan, Somayeh Gholami, Abbas Ghasemi Zad, Mara Severgnini, Francesco Longo & Faraz Kalantari. (2020) Monte Carlo simulation and analytical calculation methods to investigate the potential of nanoparticles for INTRABEAM® IORT machine. Nanomedicine: Nanotechnology, Biology and Medicine 30, pages 102288.
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Roswitha Runge, Liane Oehme, Jörg Kotzerke & Robert Freudenberg. (2016) The effect of dimethyl sulfoxide on the induction of DNA strand breaks in plasmid DNA and colony formation of PC Cl3 mammalian cells by alpha-, beta-, and Auger electron emitters 223Ra, 188Re, and 99mTc. EJNMMI Research 6:1.
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Bart Cornelissen. (2014) Imaging the inside of a tumour: a review of radionuclide imaging and theranostics targeting intracellular epitopes. Journal of Labelled Compounds and Radiopharmaceuticals 57:4, pages 310-316.
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Seyed Jalal HosseinimehrVladimir TolmachevBo Stenerlöw. (2011) 125 I-Labeled Quercetin as a Novel DNA-Targeted Radiotracer . Cancer Biotherapy and Radiopharmaceuticals 26:4, pages 469-475.
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A. I. Kassis. (2010) Molecular and cellular radiobiological effects of Auger emitting radionuclides. Radiation Protection Dosimetry 143:2-4, pages 241-247.
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Raymond M. Reilly & Amin Kassis. 2010. Monoclonal Antibody and Peptide‐Targeted Radiotherapy of Cancer. Monoclonal Antibody and Peptide‐Targeted Radiotherapy of Cancer 289 348 .
Amin I. Kassis. (2008) Therapeutic Radionuclides: Biophysical and Radiobiologic Principles. Seminars in Nuclear Medicine 38:5, pages 358-366.
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Kamal Datta, Michael Weinfeld, Ronald D. Neumann & Thomas A. Winters. (2007) Determination and Analysis of Site-Specific 125 I Decay-Induced DNA Double-Strand Break End-Group Structures . Radiation Research 167:2, pages 152-166.
Crossref
Linda S. Yasui, Kai Chen, Ketai Wang, T. Patrick Jones, James Caldwell, Diana Guse & Amin I. Kassis. (2007) Using Hoechst 33342 to Target Radioactivity to the Cell Nucleus. Radiation Research 167:2, pages 167-175.
Crossref
Kamal Datta, Ronald D. Neumann & Thomas A. Winters. (2005) Characterization of complex apurinic/apyrimidinic-site clustering associated with an authentic site-specific radiation-induced DNA double-strand break. Proceedings of the National Academy of Sciences 102:30, pages 10569-10574.
Crossref
Kai Chen, S. James Adelstein & Amin I. Kassis. (2004) Molecular modeling of the interaction of iodinated Hoechst analogs with DNA: implications for new radiopharmaceutical design. Journal of Molecular Structure: THEOCHEM 711:1-3, pages 49-56.
Crossref
Lisa Bodei, Amin I. Kassis, S. James Adelstein & Giuliano Mariani. (2003) Radionuclide Therapy with Iodine-125 and Other Auger–Electron-Emitting Radionuclides: Experimental Models and Clinical Applications. Cancer Biotherapy and Radiopharmaceuticals 18:6, pages 861-877.
Crossref
Hooshang Nikjoo & Shuzo Uehara. 2003. Charged Particle and Photon Interactions with Matter. Charged Particle and Photon Interactions with Matter.
S. James Adelstein, Amin I. Kassis, Lisa Bodei & Giuliano Mariani. (2003) Radiotoxicity of Iodine-125 and Other Auger-Electron-Emitting Radionuclides: Background to Therapy. Cancer Biotherapy and Radiopharmaceuticals 18:3, pages 301-316.
Crossref
M. A. Walicka, Y. Ding, S. J. Adelstein & A. I. Kassis. (2000) Toxicity of DNA-Incorporated Iodine-125: Quantifying the Direct and Indirect Effects. Radiation Research 154:3, pages 326-330.
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