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Research Article

More harm than good: The case against using antipsychotic drugs to prevent severe mental illness

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Pages 351-356 | Published online: 06 Jul 2009

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Jordan E. DeVylder. (2012) An Ecological Systems Perspective on the Clinical High Risk State Preceding Schizophrenia Onset. Social Work in Mental Health 10:6, pages 478-495.
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AnthonyP. Morrison, Rory Byrne & RichardP. Bentall. (2010) DSM‐5 and the ‘Psychosis Risk Syndrome’: Whose best interests would it serve?. Psychosis 2:2, pages 96-99.
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Gian Maria Galeazzi, Kathryn Elkins, Luca Pingani & Marco Rigatelli. (2006) Views on psychosis and judgment of appropriateness of early interventions in pre-psychotic phase: A survey of members of the International Early Psychosis Association. Journal of Mental Health 15:5, pages 569-576.
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Jim Van Os & Philippe Delespaul. (2005) Toward a world consensus on prevention of schizophrenia. Dialogues in Clinical Neuroscience 7:1, pages 53-67.
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Douglas Turkington & Robert Dudley. (2004) Cognitive behavioral therapy in the treatment of schizophrenia. Expert Review of Neurotherapeutics 4:5, pages 861-868.
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Susan Grey, Til Wykes & Tom Craig. (2004) There's more than one way to have an impact. Journal of Mental Health 13:4, pages 345-349.
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RICHARD WARNER. (2003) Fact versus fantasy: A reply to Bentall & Morrison. Journal of Mental Health 12:4, pages 351-357.
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SHÔN LEWIS. (2003) Is treatment research in people at high risk of psychosis ethical?. Journal of Mental Health 12:4, pages 359-362.
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ALISON YUNG & PATRICK MCGORRY. (2003) Keeping an open mind: Investigating options for treatment of the pre-psychotic phase. Journal of Mental Health 12:4, pages 341-343.
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Ian B. Kerr, Paul B. L. Birkett & Andrew Chanen. (2003) Clinical and service implications of a cognitive analytic therapy model of psychosis. Australian and New Zealand Journal of Psychiatry 37:5, pages 515-523.
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Meghan A. Collins, Jie Lisa Ji, Yoonho Chung, Cole A. Lympus, Yvette Afriyie-Agyemang, Jean M. Addington, Bradley G. Goodyear, Carrie E. Bearden, Kristin S. Cadenhead, Heline Mirzakhanian, Ming T. Tsuang, Barbara A. Cornblatt, Ricardo E. Carrión, Matcheri Keshavan, Wiliam S. Stone, Daniel H. Mathalon, Diana O. Perkins, Elaine F. Walker, Scott W. Woods, Albert R. Powers, Alan Anticevic & Tyrone D. Cannon. (2022) Accelerated cortical thinning precedes and predicts conversion to psychosis: The NAPLS3 longitudinal study of youth at clinical high-risk. Molecular Psychiatry 28:3, pages 1182-1189.
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Pete Sanders & Laurent Berthoud. (2019) La schizophrénie n’est pas une maladie. Approche Centrée sur la Personne. Pratique et recherche n° 27:1, pages 63-86.
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Olesya Ajnakina, Anthony S. David & Robin M. Murray. (2018) ‘At risk mental state’ clinics for psychosis – an idea whose time has come – and gone!. Psychological Medicine 49:4, pages 529-534.
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Miriam Larsen-Barr, Fred Seymour, John Read & Kerry Gibson. (2018) Attempting to stop antipsychotic medication: success, supports, and efforts to cope. Social Psychiatry and Psychiatric Epidemiology 53:7, pages 745-756.
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Patrick Welsh & Paul A. Tiffin. (2015) Adolescent family perceptions in the At-Risk Mental State for psychosis. Early Intervention in Psychiatry 9:4, pages 316-323.
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Hannah E. Taylor, Suzanne L. K. Stewart, Graham Dunn, Sophie Parker, David Fowler & Anthony P. Morrison. (2013) Core Schemas across the Continuum of Psychosis: A Comparison of Clinical and Non-Clinical Groups. Behavioural and Cognitive Psychotherapy 42:6, pages 718-730.
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Renaud Evrard & Thomas Rabeyron. (2014) Psychose pour tous : la jeunesse au risque du« syndrome de psychose atténuée » ?. La psychiatrie de l'enfant Vol. 57:1, pages 331-348.
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Caroline Brett, Charles Heriot-Maitland, Philip McGuire & Emmanuelle Peters. (2014) Predictors of distress associated with psychotic-like anomalous experiences in clinical and non-clinical populations. British Journal of Clinical Psychology 53:2, pages 213-227.
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David Pilgrim. (2014) Historical resonances of the DSM -5 dispute . History of the Human Sciences 27:2, pages 97-117.
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P. Hutton & P. J. Taylor. (2013) Cognitive behavioural therapy for psychosis prevention: a systematic review and meta-analysis. Psychological Medicine 44:3, pages 449-468.
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Patrick Welsh & Paul A. Tiffin. (2013) The ‘At-Risk Mental State’ for Psychosis in Adolescents: Clinical Presentation, Transition and Remission. Child Psychiatry & Human Development 45:1, pages 90-98.
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Sue Holttum & Val Huet. (2014) The MATISSE Trial–A Critique. SAGE Open 4:2, pages 215824401453293.
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Barnaby Nelson & Andrea Raballo. (2013) I disturbi nucleari del sè e gli stati mentali a rischio: uno sguardo fenomenologico al paradigma della ricerca Ultra-High Risk. RIVISTA SPERIMENTALE DI FRENIATRIA:3, pages 97-129.
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Patrick Welsh & Paul A. Tiffin. (2013) Attitudes of patients and clinicians in relation to the at-risk state for psychosis. Early Intervention in Psychiatry 7:4, pages 361-367.
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Anthony P. Morrison, Max Birchwood, Melissa Pyle, Clare Flach, Suzanne L. K. Stewart, Rory Byrne, Paul Patterson, Peter B. Jones, David Fowler, Andrew I. Gumley & Paul French. (2018) Impact of cognitive therapy on internalised stigma in people with at-risk mental states. British Journal of Psychiatry 203:2, pages 140-145.
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Patrick Welsh & Stephanie Common. (2013) The concept of folie à deux in adolescents. Clinical Psychology Forum 1:247, pages 43-46.
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Kali Brummitt & Jean Addington. (2013) Treatment possibilities for individuals at clinical high risk of psychosis. Early Intervention in Psychiatry 7:2, pages 155-161.
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Nicola Smethurst, Paul French & Anthony P. Morrison. 2013. CBT for Schizophrenia. CBT for Schizophrenia 57 85 .
Noel Hunter. (2013) Distortion, Bias, and Ethical Informed Consent: Presentations of Etiological and Treatment Factors in Abnormal Psychology Textbooks. Ethical Human Psychology and Psychiatry 15:3, pages 160-179.
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Antonio Lasalvia & Michele Tansella. (2012) ‘Young people at high risk for psychosis: conceptual framework, research evidence and treatment opportunities’. Epidemiology and Psychiatric Sciences 21:4, pages 317-322.
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Yanet Quijada, Jorge L. Tizón, Jordi Artigue, Thomas R. Kwapil & Neus Barrantes-Vidal. (2012) Attachment style predicts 6-month improvement in psychoticism in persons with at-risk mental states for psychosis. Early Intervention in Psychiatry 6:4, pages 442-449.
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Patrick Welsh & Paul A. Tiffin. (2012) Experience of child and adolescent mental health clinicians working within an at-risk mental state for psychosis service: a qualitative study. Early Intervention in Psychiatry 6:2, pages 207-211.
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J. E. Palmier‐Claus, P. J. Taylor, P. Gooding, G. Dunn & S.W. Lewis. (2011) Affective variability predicts suicidal ideation in individuals at ultra‐high risk of developing psychosis: An experience sampling study. British Journal of Clinical Psychology 51:1, pages 72-83.
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Paul Fallon, Serdar Dursun & Bill Deakin. (2011) Drug-induced supersensitivity psychosis revisited: characteristics of relapse in treatment-compliant patients. Therapeutic Advances in Psychopharmacology 2:1, pages 13-22.
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A. Bechdolf, H. Muller, H. Stutzer, M. Wagner, W. Maier, M. Lautenschlager, A. Heinz, W. de Millas, B. Janssen, W. Gaebel, T. M. Michel, F. Schneider, M. Lambert, D. Naber, M. Brune, S. Kruger-Ozgurdal, T. Wobrock, M. Riedel & J. Klosterkotter. (2011) Rationale and Baseline Characteristics of PREVENT: A Second-Generation Intervention Trial in Subjects At-Risk (Prodromal) of Developing First-Episode Psychosis Evaluating Cognitive Behavior Therapy, Aripiprazole, and Placebo for the Prevention of Psychosis. Schizophrenia Bulletin 37:suppl 2, pages S111-S121.
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Peter Smagorinsky. (2011) Confessions of a Mad Professor: An Autoethnographic Consideration of Neuroatypicality, Extranormativity, and Education. Teachers College Record: The Voice of Scholarship in Education 113:8, pages 1701-1732.
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Brynmor Lloyd-Evans, Michelle Crosby, Sarah Stockton, Stephen Pilling, Lorna Hobbs, Mark Hinton & Sonia Johnson. (2018) Initiatives to shorten duration of untreated psychosis: systematic review. British Journal of Psychiatry 198:4, pages 256-263.
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Anthony P. Morrison, Suzanne L.K. Stewart, Paul French, Richard P. Bentall, Max Birchwood, Rory Byrne, Linda M. Davies, David Fowler, Andrew I. Gumley, Peter B. Jones, Shôn W. Lewis, Graham K. Murray, Paul Patterson & Graham Dunn. (2011) Early detection and intervention evaluation for people at high-risk of psychosis-2 (EDIE-2): trial rationale, design and baseline characteristics. Early Intervention in Psychiatry 5:1, pages 24-32.
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Jean Addington, Irvin Epstein, Lu Liu, Paul French, Katherine M. Boydell & Robert B. Zipursky. (2011) A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis. Schizophrenia Research 125:1, pages 54-61.
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Jean Addington & Enza Mancuso. (2009) Cognitive‐behavioral therapy for individuals at high risk of developing psychosis. Journal of Clinical Psychology 65:8, pages 879-890.
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Barnaby Nelson, Louis A. Sass, Andrew Thompson, Alison R. Yung, Shona M. Francey, G. Paul Amminger & Patrick D. McGorry. (2009) Does disturbance of self underlie social cognition deficits in schizophrenia and other psychotic disorders?. Early Intervention in Psychiatry 3:2, pages 83-93.
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