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Special Section Review

The role of deconditioning and therapeutic exercise in chronic fatigue syndrome (CFS)

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Pages 237-252 | Published online: 06 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Kara Manning, Nubia A. Mayorga, Pamella Nizio, Luke F. Heggeness, Brooke Y. Kauffman, Lorra Garey & Michael J. Zvolensky. (2022) Exploring fatigue sensitivity in terms of mental health and fatigue severity among a racially and ethnically diverse sample with severe fatigue. Fatigue: Biomedicine, Health & Behavior 10:3, pages 136-145.
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Michiel Tack, David M. Tuller & Caroline Struthers. (2020) Bias caused by reliance on patient-reported outcome measures in non-blinded randomized trials: an in-depth look at exercise therapy for chronic fatigue syndrome. Fatigue: Biomedicine, Health & Behavior 8:4, pages 181-192.
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Joseph Cotler, Ben Z. Katz, Corine Reurts-Post, Ruud Vermeulen & Leonard A. Jason. (2020) A hierarchical logistic regression predicting rapid respiratory rates from post-exertional malaise. Fatigue: Biomedicine, Health & Behavior 8:4, pages 205-213.
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Ulric S. Abonie, Andrew M. Edwards & Florentina J. Hettinga. (2020) Optimising activity pacing to promote a physically active lifestyle in medical settings: A narrative review informed by clinical and sports pacing research. Journal of Sports Sciences 38:5, pages 590-596.
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Anne Marit Mengshoel, Ingrid Bergliot Helland, Mira Meeus, Jesus Castro-Marrero, Derek Pheby & Elin Bolle Strand. (2020) Patients’ experiences and effects of non-pharmacological treatment for myalgic encephalomyelitis/chronic fatigue syndrome – a scoping mixed methods review. International Journal of Qualitative Studies on Health and Well-being 15:1.
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Trudie Chalder. (2005) Chronic fatigue syndrome: Focus on the provider of care rather than the consumer. Journal of Mental Health 14:3, pages 209-211.
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Articles from other publishers (31)

Justina Y. W. Liu, Yue-Heng Yin, Patrick P. K. Kor, Rick Y. C. Kwan, Paul H. Lee, Wai Tong Chien, Parco M. Siu & Keith D. Hill. (2023) Effects of an individualised exercise programme plus Behavioural Change Enhancement (BCE) strategies for managing fatigue in frail older adults: a cluster randomised controlled trial. BMC Geriatrics 23:1.
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Claire Colas, Manon Bayle, Pierre Labeix, Elisabeth Botelho-Nevers, Amandine Gagneux-Brunon, Céline Cazorla, Flora Schein, Emma Breugnon, Arnauld Garcin, Léonard Feasson, Frédéric Roche & David Hupin. (2022) Management of Long COVID—The CoviMouv' Pilot Study: Importance of Adapted Physical Activity for Prolonged Symptoms Following SARS-CoV2 Infection. Frontiers in Sports and Active Living 4.
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B. L. Seves, F. Hoekstra, F. J. Hettinga, R. Dekker, L. H. V. van der Woude & T. Hoekstra. (2020) Trajectories of health-related quality of life among people with a physical disability and/or chronic disease during and after rehabilitation: a longitudinal cohort study. Quality of Life Research 30:1, pages 67-80.
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Michalina Rzepka, Mateusz Toś, Michał Boroń, Katarzyna Gibas & Ewa Krzystanek. (2020) Relationship between Fatigue and Physical Activity in a Polish Cohort of Multiple Sclerosis Patients. Medicina 56:12, pages 726.
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Donna M. Bowers, Andrea Oberlander, Kevin K. Chui, Kimberly Leigh Malin & Michelle M. Lusardi. 2020. Orthotics and Prosthetics in Rehabilitation. Orthotics and Prosthetics in Rehabilitation 38 70 .
Paweł Zalewski, Sławomir Kujawski, Malwina Tudorowska, Karl Morten, Małgorzata Tafil-Klawe, Jacek Klawe, James Strong, Fernando Estévez-López, Modra Murovska & Julia Newton. (2019) The Impact of a Structured Exercise Programme upon Cognitive Function in Chronic Fatigue Syndrome Patients. Brain Sciences 10:1, pages 4.
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Justina Y W Liu, Patrick P K Kor, Paul L Lee, Wai T Chien, Parco M Siu & Keith D Hill. (2019) Effects of an Individualized Exercise Program Plus Behavioral Change Enhancement Strategies for Managing Fatigue in Older People Who Are Frail: Protocol for a Cluster Randomized Controlled Trial. Physical Therapy 99:12, pages 1616-1627.
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Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen & Jonathan R Price. (2019) Exercise therapy for chronic fatigue syndrome. Cochrane Database of Systematic Reviews 2021:3.
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Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen & Jonathan R Price. (2017) Exercise therapy for chronic fatigue syndrome. Cochrane Database of Systematic Reviews.
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M.M. Marques, V. de Gucht, I. Leal & S. Maes. (2017) Efficacy of a randomized controlled self-regulation based physical activity intervention for chronic fatigue: Mediation effects of physical activity progress and self-regulation skills. Journal of Psychosomatic Research 94, pages 24-31.
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Lillebeth Larun, Kjetil G. Brurberg, Jan Odgaard-Jensen & Jonathan R Price. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Lillebeth Larun, Kjetil G. Brurberg, Jan Odgaard-Jensen & Jonathan R Price. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Charlotte Russell, Alison J. Wearden, Gillian Fairclough, Richard A. Emsley & Simon D. Kyle. (2016) Subjective but Not Actigraphy-Defined Sleep Predicts Next-Day Fatigue in Chronic Fatigue Syndrome: A Prospective Daily Diary Study. Sleep 39:4, pages 937-944.
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Lillebeth Larun, Kjetil G. Brurberg, Jan Odgaard-Jensen & Jonathan R Price. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
M.M. Marques, V. De Gucht, M.J. Gouveia, I. Leal & S. Maes. (2015) Differential effects of behavioral interventions with a graded physical activity component in patients suffering from Chronic Fatigue (Syndrome): An updated systematic review and meta-analysis. Clinical Psychology Review 40, pages 123-137.
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M. Marques, V. De Gucht, I. Leal & S. Maes. (2014) Effects of a Self-regulation Based Physical Activity Program (The “4-STEPS”) for Unexplained Chronic Fatigue: a Randomized Controlled Trial. International Journal of Behavioral Medicine 22:2, pages 187-196.
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Lillebeth Larun, Kjetil G. Brurberg, Jan Odgaard-Jensen & Jonathan R Price. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Noah D. Silverberg & Grant L. Iverson. (2013) Is Rest After Concussion “The Best Medicine?”. Journal of Head Trauma Rehabilitation 28:4, pages 250-259.
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Michelle M. Lusardi & Donna M. Bowers. 2013. Orthotics and Prosthetics in Rehabilitation. Orthotics and Prosthetics in Rehabilitation 38 71 .
Rona Moss-Morris, Vincent Deary & Bronwyn Castell. 2013. Neurological Rehabilitation. Neurological Rehabilitation 303 314 .
Kamaldeep S Bhui, Sokratis Dinos, Deborah Ashby, James Nazroo, Simon Wessely & Peter D White. (2011) Chronic fatigue syndrome in an ethnically diverse population: the influence of psychosocial adversity and physical inactivity. BMC Medicine 9:1.
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Bronwyn D. Castell, Nikolaos Kazantzis & Rona E. Moss-Morris. (2011) Cognitive behavioral therapy and graded exercise for chronic fatigue syndrome: A meta‐analysis.. Clinical Psychology: Science and Practice 18:4, pages 311-324.
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Francis Creed, Kurt Kroenke, Peter Henningsen, Alka Gudi & Peter White. 2011. Medically Unexplained Symptoms, Somatisation and Bodily Distress. Medically Unexplained Symptoms, Somatisation and Bodily Distress 69 96 .
Lillebeth Larun & Kirsti Malterud. (2011) Finding the right balance of physical activity. Patient Education and Counseling 83:2, pages 222-226.
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Laura Goodwin, Peter D. White, Matthew Hotopf, Stephen A. Stansfeld & Charlotte Clark. (2011) Psychopathology and Physical Activity as Predictors of Chronic Fatigue Syndrome in the 1958 British Birth Cohort: A Replication Study of the 1946 and 1970 Birth Cohorts. Annals of Epidemiology 21:5, pages 343-350.
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Lillebeth Larun & Kirsti Malterud. (2011) Treningsbehandling ved kronisk utmattelsessyndrom. Tidsskrift for Den norske legeforening 131:3, pages 231-236.
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J. L. Newton & D. E. J. Jones. (2010) Making sense of fatigue. Occupational Medicine 60:5, pages 326-329.
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Daniela Schwarz, Jürgen Gießing, Jens Heider, Alexandra Zaby & Annette Schröder. (2009) Sporttherapiein der Behandlung somatoformer Beschwerden. Zeitschrift für Sportpsychologie 16:4, pages 117-130.
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Jonathan R Price, Edward Mitchell, Elizabeth Tidy & Vivien Hunot. (2008) Cognitive behaviour therapy for chronic fatigue syndrome in adults. Cochrane Database of Systematic Reviews 2021:3.
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B. Van HoudenhoveL. VerheyenK. PardaensP. Luyten & P. Van Wambeke. (2007) Rehabilitation of decreased motor performance in patients with chronic fatigue syndrome: should we treat low effort capacity or reduced effort tolerance?. Clinical Rehabilitation 21:12, pages 1121-1142.
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V. Deary, T. Chalder & M. Sharpe. (2007) The cognitive behavioural model of medically unexplained symptoms: A theoretical and empirical review. Clinical Psychology Review 27:7, pages 781-797.
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