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Research Article

Extent of the selectivity filter conferred by the sixth transmembrane region in the CFTR chloride channel pore

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Pages 45-52 | Published online: 09 Jul 2009

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Paul Linsdell. (2014) Functional architecture of the CFTR chloride channel. Molecular Membrane Biology 31:1, pages 1-16.
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Articles from other publishers (15)

Alexander Negoda, Mairin S. Hogan, Elizabeth A. Cowley & Paul Linsdell. (2019) Contribution of the eighth transmembrane segment to the function of the CFTR chloride channel pore. Cellular and Molecular Life Sciences 76:12, pages 2411-2423.
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Alexander Negoda, Yassine El Hiani, Elizabeth A. Cowley & Paul Linsdell. (2017) Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel. Biochimica et Biophysica Acta (BBA) - Biomembranes 1859:5, pages 1049-1058.
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Paul Linsdell. (2016) Architecture and functional properties of the CFTR channel pore. Cellular and Molecular Life Sciences 74:1, pages 67-83.
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Jean-Paul Mornon, Brice Hoffmann, Slavica Jonic, Pierre Lehn & Isabelle Callebaut. (2014) Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics. Cellular and Molecular Life Sciences 72:7, pages 1377-1403.
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D. N. Orlov & N. Ya. Orlov. (2009) Nucleoside diphosphate kinase and GTP-binding proteins. Possible mechanisms of coupling. Biophysics 53:6, pages 482-487.
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Edward J. Beck, Yu Yang, Sirin Yaemsiri & Viswanathan Raghuram. (2008) Conformational Changes in a Pore-lining Helix Coupled to Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating. Journal of Biological Chemistry 283:8, pages 4957-4966.
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Annie Frelet & Markus Klein. (2006) Insight in eukaryotic ABC transporter function by mutation analysis. FEBS Letters 580:4, pages 1064-1084.
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Paul Linsdell. (2006) Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel. Experimental Physiology 91:1, pages 123-129.
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Paul Linsdell. (2005) Location of a Common Inhibitor Binding Site in the Cytoplasmic Vestibule of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore. Journal of Biological Chemistry 280:10, pages 8945-8950.
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Ning Ge, Chantal N. Muise, Xiandi Gong & Paul Linsdell. (2004) Direct Comparison of the Functional Roles Played by Different Transmembrane Regions in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore. Journal of Biological Chemistry 279:53, pages 55283-55289.
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Eva Y. Chen, M. Claire Bartlett, Tip W. Loo & David M. Clarke. (2004) The ΔF508 Mutation Disrupts Packing of the Transmembrane Segments of the Cystic Fibrosis Transmembrane Conductance Regulator. Journal of Biological Chemistry 279:38, pages 39620-39627.
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Da-Wei Zhang, Kenichi Nunoya, Monika Vasa, Hong-Mei Gu, Ashley Theis, Susan P. C. Cole & Roger G. Deeley. (2004) Transmembrane Helix 11 of Multidrug Resistance Protein 1 (MRP1/ABCC1):  Identification of Polar Amino Acids Important for Substrate Specificity and Binding of ATP at Nucleotide Binding Domain 1. Biochemistry 43:29, pages 9413-9425.
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Xiandi Gong & Paul Linsdell. (2004) Maximization of the rate of chloride conduction in the CFTR channel pore by ion–ion interactions. Archives of Biochemistry and Biophysics 426:1, pages 78-82.
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Xiandi Gong & Paul Linsdell. (2003) Mutation-induced Blocker Permeability and Multiion Block of the CFTR Chloride Channel Pore. The Journal of General Physiology 122:6, pages 673-687.
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Zhiwei Cai, Toby S. Scott-Ward & David N. Sheppard. (2003) Voltage-dependent Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channel. The Journal of General Physiology 122:5, pages 605-620.
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