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Molecular Membrane Biology Volume 20, 2003 - Issue 1
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Research Article

Neither lipophilicity nor membrane-perturbing potency of phenothiazine maleates correlate with the ability to inhibit P-glycoprotein transport activity

Andrzej B. Hendrich Department of Biophysics Wrocław Medical University ul. Chalubinskiego 10 50-368 Wrocław
,
Olga Wesołowska Department of Biophysics Wrocław Medical University ul. Chalubinskiego 10 50-368 Wrocław
,
Andrzej Poła Department of Biophysics Wrocław Medical University ul. Chalubinskiego 10 50-368 Wrocław
,
Noboru Motohashi Meiji Pharmaceutical University 2-522-1 Noshio 204-8588 Kiyose-shi, Tokyo
,
Joseph Molnár Institute of Microbiology Albert Szent-Györgyi Medical University Dom ter 10 H-6720 Szeged
&
Krystyna Michalak Department of Biophysics Wrocław Medical University ul. Chalubinskiego 10 50-368 Wrocław
Pages 53-60 | Published online: 09 Jul 2009

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Jiřina Procházková, Lukáš Kubala, Hana Kotasová, Iva Gudernová, Zuzana Šrámková, Michaela Pekarová, Balázs Sarkadi & Jiří Pacherník. (2011) ABC transporters affect the detection of intracellular oxidants by fluorescent probes. Free Radical Research 45:7, pages 779-787.
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Marcelo B. D. Borges, Carolina G. Dos Santos, César H. Yokomizo, Rohit Sood, Pavol Vitovic, Paavo K. J. Kinnunen, Tiago Rodrigues & Iseli L. Nantes. (2010) Characterization of hydrophobic interaction and antioxidant properties of the phenothiazine nucleus in mitochondrial and model membranes. Free Radical Research 44:9, pages 1054-1063.
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Articles from other publishers (9)

Stephanie Andrade, Maria J. Ramalho, Joana A. Loureiro & Maria Carmo Pereira. (2019) Interaction of natural compounds with biomembrane models: A biophysical approach for the Alzheimer’s disease therapy. Colloids and Surfaces B: Biointerfaces 180, pages 83-92.
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Carolina G. dos Santos, André L. Silva, Flavio L. Souza, Alexandre J. C. Lanfredi, Paolo Di Mascio, Otaciro R. Nascimento, Tiago Rodrigues & Iseli L. Nantes. (2013) UV-Light Effects on Cytochrome C Modulated by the Aggregation State of Phenothiazines. PLoS ONE 8:10, pages e76857.
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Patrícia T. Martins, Adrian Velazquez-Campoy, Winchil L. C. Vaz, Renato M. S. Cardoso, Joana Valério & Maria João Moreno. (2012) Kinetics and Thermodynamics of Chlorpromazine Interaction with Lipid Bilayers: Effect of Charge and Cholesterol. Journal of the American Chemical Society 134:9, pages 4184-4195.
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Agata Jaszczyszyn, Kazimierz Gąsiorowski, Piotr Świątek, Wiesław Malinka, Katarzyna Cieślik-Boczula, Joanna Petrus & Bogusława Czarnik-Matusewicz. (2012) Chemical structure of phenothiazines and their biological activity. Pharmacological Reports 64:1, pages 16-23.
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Cláudia Nunes, Gerald Brezesinski, Daniela Lopes, José L.F.C. Lima, Salette Reis & Marlene Lúcio. (2011) Lipid–Drug Interaction: Biophysical Effects of Tolmetin on Membrane Mimetic Systems of Different Dimensionality. The Journal of Physical Chemistry B 115:43, pages 12615-12623.
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Marcin Kolaczkowski, Anna Kolaczkowska, Noboru Motohashi & Krystyna Michalak. (2009) New High-Throughput Screening Assay To Reveal Similarities and Differences in Inhibitory Sensitivities of Multidrug ATP-Binding Cassette Transporters. Antimicrobial Agents and Chemotherapy 53:4, pages 1516-1527.
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K. Michalak, O. Wesołowska, N. Motohashi & A. B. Hendrich. 2007. Bioactive Heterocycles II. Bioactive Heterocycles II 223 302 .
Andreas Hilgeroth, Annamária Molnár, Josef Molnár & Burkhardt Voigt. (2006) Correlation of calculated molecular orbital energies of some phenothiazine compounds with MDR reversal properties. European Journal of Medicinal Chemistry 41:4, pages 548-551.
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Olga Wesołowska, Daniela Mosiądz, Noboru Motohashi, Masami Kawase & Krystyna Michalak. (2005) Phenothiazine maleates stimulate MRP1 transport activity in human erythrocytes. Biochimica et Biophysica Acta (BBA) - Biomembranes 1720:1-2, pages 52-58.
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