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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 6, 2003 - Issue 1
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Research Article

The Short-term Effects of Fasting on the Neuroendocrine System in Patients with Chronic Pain Syndromes

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Pages 11-18 | Published online: 05 Sep 2013

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Brandon A. Kohrt, Carol M. Worthman, Kerry J. Ressler, Kristina B. Mercer, Nawaraj Upadhaya, Suraj Koirala, Mahendra K. Nepal, Vidya Dev Sharma & Elisabeth B. Binder. (2015) Cross-cultural gene− environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: polymorphisms and childhood trauma in South Asia. International Review of Psychiatry 27:3, pages 180-196.
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Andreas Michalsen, Martin K. Kuhlmann, Rainer Lüdtke, Marcus Bäcker, Jost Langhorst & Gustav J. Dobos. (2006) Prolonged fasting in patients with chronic pain syndromes leads to late mood-enhancement not related to weight loss and fasting-induced leptin depletion. Nutritional Neuroscience 9:5-6, pages 195-200.
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Articles from other publishers (31)

Krzysztof Stec, Karol Pilis, Wiesław Pilis, Paweł Dolibog, Sławomir Letkiewicz & Alicja Głębocka. (2023) Effects of Fasting on the Physiological and Psychological Responses in Middle-Aged Men. Nutrients 15:15, pages 3444.
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Jingjing Liu & Stanley Sau Ching Wong. (2022) Molecular Mechanisms and Pathophysiological Pathways of High-Fat Diets and Caloric Restriction Dietary Patterns on Pain. Anesthesia & Analgesia 137:1, pages 137-152.
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Daniela A. Koppold, Farid I. Kandil, Oliver Güttler, Anna Müller, Nico Steckhan, Sara Meiß, Carolin Breinlinger, Esther Nelle, Anika M. Hartmann, Michael Jeitler, Etienne Hanslian, Jan Moritz Fischer, Andreas Michalsen & Christian S. Kessler. (2023) Effects of Prolonged Fasting during Inpatient Multimodal Treatment on Pain and Functional Parameters in Knee and Hip Osteoarthritis: A Prospective Exploratory Observational Study. Nutrients 15:12, pages 2695.
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Jesse P. Caron, Margaret Ann Kreher, Angela M. Mickle, Stanley Wu, Rene Przkora, Irene M. Estores & Kimberly T. Sibille. (2022) Intermittent Fasting: Potential Utility in the Treatment of Chronic Pain across the Clinical Spectrum. Nutrients 14:12, pages 2536.
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Georg Juckel, Anne Berghöfer & Knut Hoffmann. 2022. Therapieresistenz bei Depressionen und bipolaren Störungen. Therapieresistenz bei Depressionen und bipolaren Störungen 373 403 .
Chao Yang, Qianying Ma, Hongyu Zhang, Feng Wu, Manrui Wu, Chengjia Yang, Ying Chen, Jianghui Xiong, Wenjuan Liu, Hailong Wang, Ruilin Wu, Zhongquan Dai & Yinghui Li. (2021) Ten days of complete fasting affected subjective sensations but not cognitive abilities in healthy adults. European Journal of Nutrition 60:5, pages 2747-2758.
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Hyndavi Salwa & Pradeep M.K. Nair. (2021) Raising burden of non-communicable diseases: importance of integrating Yoga and Naturopathy at primary care level. Journal of Complementary and Integrative Medicine 18:2, pages 271-278.
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Daniela Koppold-Liebscher, Christian S. Kessler, Nico Steckhan, Vanessa Bähr, Cornelia Kempter, Manfred Wischnewsky, Marisa Hübner, Barbara Kunz, Marion Paul, Stefanie Zorn, Sophia Sari, Michael Jeitler, Rainer Stange & Andreas Michalsen. (2020) Short-term fasting accompanying chemotherapy as a supportive therapy in gynecological cancer: protocol for a multicenter randomized controlled clinical trial. Trials 21:1.
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Yong Liu, Aiwu Cheng, Yu-Jiao Li, Ying Yang, Yuki Kishimoto, Shi Zhang, Yue Wang, Ruiqian Wan, Sophia M. Raefsky, Daoyuan Lu, Takashi Saito, Takaomi Saido, Jian Zhu, Long-Jun Wu & Mark P. Mattson. (2019) SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice. Nature Communications 10:1.
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Françoise Wilhelmi de Toledo, Franziska Grundler, Audrey Bergouignan, Stefan Drinda & Andreas Michalsen. (2019) Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects. PLOS ONE 14:1, pages e0209353.
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Stephan P. Bauersfeld, Christian S. Kessler, Manfred Wischnewsky, Annette Jaensch, Nico Steckhan, Rainer Stange, Barbara Kunz, Barbara Brückner, Jalid Sehouli & Andreas Michalsen. (2018) The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study. BMC Cancer 18:1.
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Stefan Drinda, Sybille Franke, Sebastian Schmidt, Katrin Stoy, Thomas Lehmann, Gunter Wolf & Thomas Neumann. (2018) AGE-RAGE Interaction Does Not Explain the Clinical Improvements after Therapeutic Fasting in Osteoarthritis. Complementary Medicine Research 25:3, pages 167-172.
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Eva Lischka & Norbert Lischka. 2018. Ernährung und Fasten als Therapie. Ernährung und Fasten als Therapie 197 205 .
Kyle M. Schachtschneider, Yingkai Liu, Laurie A. Rund, Ole Madsen, Rodney W. Johnson, Martien A. M. Groenen & Lawrence B. Schook. (2016) Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development. BMC Genomics 17:1.
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Frederick G. Strathmann, Stefanie Schulte, Kyle Goerl & David J. Petron. (2014) Blood-based biomarkers for traumatic brain injury: Evaluation of research approaches, available methods and potential utility from the clinician and clinical laboratory perspectives. Clinical Biochemistry 47:10-11, pages 876-888.
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Rajiv Rastogi & Devesh Rastogi. 2014. Ayurvedic Science of Food and Nutrition. Ayurvedic Science of Food and Nutrition 123 135 .
Guillaume Fond, Alexandra Macgregor, Marion Leboyer & Andreas Michalsen. (2013) Fasting in mood disorders: neurobiology and effectiveness. A review of the literature. Psychiatry Research 209:3, pages 253-258.
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Andreas Michalsen, Chenying Li, Katharina Kaiser, Rainer Lüdtke, Larissa Meier, Rainer Stange & Christian Kessler. (2013) In-Patient Treatment of Fibromyalgia: A Controlled Nonrandomized Comparison of Conventional Medicine versus Integrative Medicine including Fasting Therapy. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-7.
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Katrin Schulz, Chris D. Vulpe, Leah Z. Harris & Samuel David. (2011) Iron Efflux from Oligodendrocytes Is Differentially Regulated in Gray and White Matter. The Journal of Neuroscience 31:37, pages 13301-13311.
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Andreas Michalsen. (2010) Prolonged Fasting as a Method of Mood Enhancement in Chronic Pain Syndromes: A Review of Clinical Evidence and Mechanisms. Current Pain and Headache Reports 14:2, pages 80-87.
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Timo D. Müller, Manuel Föcker, Kristian Holtkamp, Beate Herpertz-Dahlmann & Johannes Hebebrand. (2009) Leptin-Mediated Neuroendocrine Alterations in Anorexia Nervosa: Somatic and Behavioral Implications. Child and Adolescent Psychiatric Clinics of North America 18:1, pages 117-129.
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A. Michalsen, A. Bierhaus, P. P. Nawroth & G. J. Dobos. (2006) Glykotoxine und ZellaktivierungGlycotoxins and cellular dysfunction. A new mechanism for understanding the preventive effects of lifestyle modifications. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 49:8, pages 773-779.
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J. Shao, G. Xi, Y. Hua, T. Schallert & B. T. Felt. 2006. Brain Edema XIII. Brain Edema XIII 183 187 .
Andreas Michalsen, Markus Riegert, Rainer Lüdtke, Marcus Bäcker, Jost Langhorst, Myriam Schwickert & Gustav J Dobos. (2005) Mediterranean diet or extended fasting's influence on changing the intestinal microflora, immunoglobulin A secretion and clinical outcome in patients with rheumatoid arthritis and fibromyalgia: an observational study. BMC Complementary and Alternative Medicine 5:1.
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Andreas MichalsenBarbara HoffmannSusanne MoebusMarkus BäckerJost LanghorstGustav J. Dobos. (2005) Incorporation of Fasting Therapy in an Integrative Medicine Ward: Evaluation of Outcome, Safety, and Effects on Lifestyle Adherence in a Large Prospective Cohort Study. The Journal of Alternative and Complementary Medicine 11:4, pages 601-607.
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Jeffrey T Junig & Jon A Lehrmann. (2005) A psychotic episode associated with the Atkins Diet in a patient with bipolar disorder. Bipolar Disorders 7:3, pages 305-306.
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Joseph R. Prohaska & Anna A. Gybina. (2005) Rat brain iron concentration is lower following perinatal copper deficiency. Journal of Neurochemistry 93:3, pages 698-705.
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Julia Pönicke, Birgit Albacht & Bernd Leplow. (2005) Kognitive Veränderungen beim Fasten. Zeitschrift für Klinische Psychologie und Psychotherapie 34:2, pages 86-94.
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A. Rodenbeck, G. Hüther & E. Rüther. 2005. Das serotonerge System aus neurologischer und psychiatrischer Sicht. Das serotonerge System aus neurologischer und psychiatrischer Sicht 1 10 .
J. R. Connor, X. S. Wang, S. M. Patton, S. L. Menzies, J. C. Troncoso, C. J. Earley & R. P. Allen. (2004) Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome. Neurology 62:9, pages 1563-1567.
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John L. Beard, Jason A. Wiesinger & James R. Connor. (2003) Pre- and Postweaning Iron Deficiency Alters Myelination in Sprague-Dawley Rats. Developmental Neuroscience 25:5, pages 308-315.
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