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Research Article

Biochemistry, Physiology, and Complications of Blood Doping: Facts and Speculation

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Pages 349-391 | Published online: 10 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Gian Luca Salvagno, Fabian Sanchis-Gomar, Alessandra Picanza & Giuseppe Lippi. (2015) Red blood cell distribution width: A simple parameter with multiple clinical applications. Critical Reviews in Clinical Laboratory Sciences 52:2, pages 86-105.
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Carolina Dizioli Rodrigues de Oliveira, André Valle de Bairros & Mauricio Yonamine. (2014) Blood Doping: Risks to Athletes’ Health and Strategies for Detection. Substance Use & Misuse 49:9, pages 1168-1181.
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AngelaJ. Schneider, MatthewN. Fedoruk & JimL. Rupert. (2012) Human genetic variation: New challenges and opportunities for doping control. Journal of Sports Sciences 30:11, pages 1117-1129.
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Giuseppe Lippi, Mario Plebani, Salvatore Di Somma & Gianfranco Cervellin. (2011) Hemolyzed specimens: a major challenge for emergency departments and clinical laboratories. Critical Reviews in Clinical Laboratory Sciences 48:3, pages 143-153.
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Articles from other publishers (37)

Jo Morrison. (2023) Lack of evidence that doping is harmful to the health of elite athletes. Performance Enhancement & Health 11:1, pages 100245.
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Na Li & Wenli Chu. (2023) Development and validation of a survival prediction model in elder patients with community-acquired pneumonia: a MIMIC-population-based study. BMC Pulmonary Medicine 23:1.
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Qiang Ren, Hebing Liu, Ying Wang, Deyu Dai, Zhennan Tian, Guiwei Jiao & Xiaomin Liu. (2021) The Role of Red Blood Cell Distribution Width in the Severity and Prognosis of Community-Acquired Pneumonia. Canadian Respiratory Journal 2021, pages 1-9.
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Mae Jemison & Ronke Olabisi. (2021) Biomaterials for human space exploration: A review of their untapped potential. Acta Biomaterialia 128, pages 77-99.
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Jan Sommer Jeppesen, Andreas Breenfeldt Andersen, Thomas Christian Bonne, Martin Thomassen, Helle Sørensen, Nikolai Baastrup Nordsborg, Niels Vidiendal Olsen, Jesús Rodríguez Huertas & Jacob Bejder. (2021) Immature reticulocytes are sensitive and specific to low‐dose erythropoietin treatment at sea level and altitude. Drug Testing and Analysis 13:7, pages 1331-1340.
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Benedikt Seeger & Marijke Grau. (2020) Relation between Exercise Performance and Blood Storage Condition and Storage Time in Autologous Blood Doping. Biology 10:1, pages 14.
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Erick J. Richmond & Alan D. Rogol. 2020. Endocrinology of Physical Activity and Sport. Endocrinology of Physical Activity and Sport 507 518 .
Donatella PozElena De FalcoCalogera PisanoRosalinda MadonnaPeter FerdinandyCarmela Rita Balistreri. (2019) Diagnostic and Prognostic Relevance of Red Blood Cell Distribution Width for Vascular Aging and Cardiovascular Diseases. Rejuvenation Research 22:2, pages 146-162.
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Giuseppe Lippi & Camilla Mattiuzzi. (2017) Misuse of the metabolic modulator meldonium in sports. Journal of Sport and Health Science 6:1, pages 49-51.
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Jacob Bejder, Niels Jacob Aachmann-Andersen, Thomas Christian Bonne, Niels Vidiendal Olsen & Nikolai Baastrup Nordsborg. (2016) Detection of erythropoietin misuse by the Athlete Biological Passport combined with reticulocyte percentage. Drug Testing and Analysis 8:10, pages 1049-1055.
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K.D. Rainsford. 2015. Ibuprofen. Ibuprofen 313 345 .
Giuseppe Lippi, Gian Luca Salvagno, Elisa Danese, Spyros Skafidas, Cantor Tarperi, Gian Cesare Guidi & Federico Schena. (2014) Mean Platelet Volume (MPV) Predicts Middle Distance Running Performance. PLoS ONE 9:11, pages e112892.
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Grigory Krotov, Maria Nikitina & Grigory Rodchenkov. (2014) Possible cause of lack of positive samples on homologous blood transfusion. Drug Testing and Analysis 6:11-12, pages 1160-1162.
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Giuseppe Lippi, Camilla Mattiuzzi & Fabian Sanchis-Gomar. (2014) Mean speed in professional cycling: No evidence of decline. Performance Enhancement & Health 3:1, pages 45-48.
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Irina Manokhina & James L Rupert. (2013) A DNA-based method for detecting homologous blood doping. Analytical and Bioanalytical Chemistry 405:30, pages 9693-9701.
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Leonidas H. Duntas & Vera Popovic. (2012) Hormones as doping in sports. Endocrine 43:2, pages 303-313.
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Erick J. Richmond & Alan D. Rogol. 2013. Endocrinology of Physical Activity and Sport. Endocrinology of Physical Activity and Sport 535 546 .
Zoran Nikolovski, Carolina De La Torre, Cristina Chiva, Eva Borràs, David Andreu, Rosa Ventura & Jordi Segura. (2012) Alterations of the erythrocyte membrane proteome and cytoskeleton network during storage - a possible tool to identify autologous blood transfusion. Drug Testing and Analysis 4:11, pages 882-890.
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Donald G. BarcelouxJames Rhee & Timothy Erickson. 2012. Medical Toxicology of Drug Abuse. Medical Toxicology of Drug Abuse 306 325 .
Raimon Guitart & Nuria Giménez. (2012) ¿Qué es un «tóxico»? Una propuesta de definición. Medicina Clínica 138:3, pages 127-132.
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Mario Zorzoli. (2011) Biological passport parameters. Journal of Human Sport and Exercise 6:2 (Suppl.), pages 205-217.
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Giuseppe Lippi, Martina Montagnana & Massimo Franchini. (2011) Ex-vivo red blood cells generation: A step ahead in transfusion medicine?. European Journal of Internal Medicine 22:1, pages 16-19.
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Giuseppe Lippi & Mario Plebani. (2011) Athlete's biological passport: to test or not to test?. Clinical Chemistry and Laboratory Medicine 49:9.
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Jordi Segura & Mario Zorzoli. 2011. Hormone Use and Abuse by Athletes. Hormone Use and Abuse by Athletes 151 161 .
Giuseppe Lippi, Giuseppe Banfi & Nicola Maffulli. (2010) Preanalytical variability: the dark side of the moon in blood doping screening. European Journal of Applied Physiology 109:5, pages 1003-1005.
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Giuseppe Lippi & Massimo Franchini. (2009) Intermittent hypoxic training: doping or what?. European Journal of Applied Physiology 108:2, pages 411-412.
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Hassan M. E. Azzazy. 2010. Doping in Sports. Doping in Sports 485 512 .
Patricia A. Arndt & Belinda M. Kumpel. (2008) Blood doping in athletes-Detection of allogeneic blood transfusions by flow cytofluorometry. American Journal of Hematology 83:8, pages 657-667.
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S Elliott. (2008) Erythropoiesis-stimulating agents and other methods to enhance oxygen transport. British Journal of Pharmacology 154:3, pages 529-541.
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D J Wells. (2008) Gene doping: the hype and the reality. British Journal of Pharmacology 154:3, pages 623-631.
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Folke Sjöqvist, Mats Garle & Anders Rane. (2008) Use of doping agents, particularly anabolic steroids, in sports and society. The Lancet 371:9627, pages 1872-1882.
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M Kiuru & R G Crystal. (2008) Progress and prospects: gene therapy for performance and appearance enhancement. Gene Therapy 15:5, pages 329-337.
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Joris R. Delanghe, Mathieu Bollen & Monique Beullens. (2007) Testing for recombinant erythropoietin. American Journal of Hematology 83:3, pages 237-241.
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Mario Thevis, Andreas Thomas & Wilhelm Schänzer. (2008) Mass spectrometric determination of insulins and their degradation products in sports drug testing. Mass Spectrometry Reviews 27:1, pages 35-50.
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Giuseppe LippiMassimo FranchiniGian Cesare Guidi. (2007) Prohibition of artificial hypoxic environments in sports: health risks rather than ethics. Applied Physiology, Nutrition, and Metabolism 32:6, pages 1206-1207.
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JAKOB MORKEBERG, CARSTEN LUNDBY, GRO NISSEN-LIE, THOMAS KJAEREM NIELSEN, PETER HEMMERSBACH & RASMUS DAMSGAARD. (2007) Detection of Darbepoetin Alfa Misuse in Urine and Blood. Medicine & Science in Sports & Exercise 39:10, pages 1742-1747.
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Giuseppe Lippi & Giuseppe Banfi. (2006) Blood transfusions in athletes. Old dogmas, new tricks. Clinical Chemistry and Laboratory Medicine (CCLM) 44:12.
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