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Research Article

Mode of Action: Angiotensin-Converting Enzyme Inhibition—Developmental Effects Associated With Exposure to ACE Inhibitors

Pages 747-755 | Published online: 10 Oct 2008

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Read on this site (4)

M. MacKintosh, C. Tower, B. Clarke & S. Vause. (2010) Anhydramnios secondary to angiotensin II converting enzyme inhibitors: A reversible condition?. Journal of Obstetrics and Gynaecology 30:8, pages 865-866.
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Jeffrey A Kramer. (2008) Designing safe drugs: what to consider?. Expert Opinion on Drug Discovery 3:7, pages 707-713.
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KathrynZ. Guyton, Stanley Barone$suffix/text()$suffix/text(), RebeccaC. Brown, SusanY. Euling, Jennifer Jinot & Susan Makris. (2008) Mode of Action Frameworks: A Critical Analysis. Journal of Toxicology and Environmental Health, Part B 11:1, pages 16-31.
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Alan R. Boobis, John E. Doe, Barbara Heinrich-Hirsch, M. E. (Bette) Meek, Sharon Munn, Mathuros Ruchirawat, Josef Schlatter, Jennifer Seed & Carolyn Vickers. (2008) IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans. Critical Reviews in Toxicology 38:2, pages 87-96.
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Articles from other publishers (22)

Hui-Kim Yap & Perry Yew-Weng Lau. 2023. Pediatric Kidney Disease. Pediatric Kidney Disease 373 404 .
Wenyue Zheng, Erkang Tian, Zhen Liu, Changhan Zhou, Pei Yang, Keyue Tian, Wen Liao, Juan Li & Changyu Ren. (2022) Small molecule angiotensin converting enzyme inhibitors: A medicinal chemistry perspective. Frontiers in Pharmacology 13.
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Kendall S. Frazier. (2021) The Impact of Functional and Structural Maturation of the Kidney on Susceptibility to Drug and Chemical Toxicity in Neonatal Rodents. Toxicologic Pathology 49:8, pages 1377-1388.
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Jean‐Yu Hwang, Wei‐Chih Kan, Yao‐Bin Liu, Lea‐Yea Chuang, Jinn‐Yuh Guh, Yu‐Lin Yang & Jau‐Shyang Huang. (2019) Angiotensin‐converting enzyme inhibitors attenuated advanced glycation end products‐induced renal tubular hypertrophy via enhancing nitric oxide signaling. Journal of Cellular Physiology 234:10, pages 17473-17481.
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Kendall S. Frazier. (2017) Species Differences in Renal Development and Associated Developmental Nephrotoxicity. Birth Defects Research 109:16, pages 1243-1256.
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E. Koch & S. Plassmann. 2017. A Comprehensive Guide to Toxicology in Nonclinical Drug Development. A Comprehensive Guide to Toxicology in Nonclinical Drug Development 7 38 .
Jude S. Morton, Christy-Lynn Cooke & Sandra T. Davidge. (2016) In Utero Origins of Hypertension: Mechanisms and Targets for Therapy. Physiological Reviews 96:2, pages 549-603.
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Hui-Kim Yap & Perry Yew-Weng Lau. 2016. Pediatric Kidney Disease. Pediatric Kidney Disease 391 418 .
Norikazu Ueki, Satoru Takeda, Daisuke Koya & Keizo Kanasaki. (2015) The Relevance of the Renin-Angiotensin System in the Development of Drugs to Combat Preeclampsia. International Journal of Endocrinology 2015, pages 1-12.
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J Koo & A Zavras. (2013) Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation. Oral Diseases 19:7, pages 712-720.
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Young Joo Jeon, Ji Hyang Kim, Bo Eun Lee, HyungChul Rah, Ji Eun Shin, Hojeong Kang, Dong Hee Choi, Tae Ki Yoon, Woo Sik Lee, Sung Han Shim & Nam Keun Kim. (2013) Association between Polymorphisms in the Renin-Angiotensin System Genes and Prevalence of Spontaneously Aborted Fetuses. American Journal of Reproductive Immunology 70:3, pages 238-245.
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Leeann M. Bellamy, Adam P. W. Johnston, Michael De Lisio & Gianni Parise. (2010) Skeletal muscle-endothelial cell cross talk through angiotensin II. American Journal of Physiology-Cell Physiology 299:6, pages C1402-C1408.
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Dianne B. McKay & Michelle Josephson. (2010) Pregnancy in renal transplant recipients. Dialysis & Transplantation 39:11, pages 472-475.
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Roland Lennestål, Petra Otterblad Olausson & Bengt Källén. (2009) Maternal use of antihypertensive drugs in early pregnancy and delivery outcome, notably the presence of congenital heart defects in the infants. European Journal of Clinical Pharmacology 65:6, pages 615-625.
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A.Y. Ponstein-Simarro Doorten, J.A.G. vd Wiel & D. Jonker. (2009) Safety evaluation of an IPP tripeptide-containing milk protein hydrolysate. Food and Chemical Toxicology 47:1, pages 55-61.
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Aarif Y. Khakoo, Richard L. Sidman, Renata Pasqualini & Wadih Arap. (2008) Does the Renin-Angiotensin System Participate in Regulation of Human Vasculogenesis and Angiogenesis?. Cancer Research 68:22, pages 9112-9115.
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U. Martin, M. A. Foreman, J. C. Travis, D. Casson & J. J. Coleman. (2008) Use of ACE inhibitors and ARBs in hypertensive women of childbearing age. Journal of Clinical Pharmacy and Therapeutics 33:5, pages 507-511.
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Jaime L. Frías & Enid Gilbert-Barness. (2008) Human Teratogens: Current Controversies. Advances in Pediatrics 55:1, pages 171-211.
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Hui-Kim Yap & Perry Yew-Weng Lau. 2008. Comprehensive Pediatric Nephrology. Comprehensive Pediatric Nephrology 179 193 .
Rebecca L Branch & Una Martin. (2007) Adverse effects of angiotensin-converting enzyme inhibitors and Angiotensin-II receptor blockers in pregnancy. Adverse Drug Reaction Bulletin &NA;:246, pages 943-946.
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Jeffrey A. Kramer, John E. Sagartz & Dale L. Morris. (2007) The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates. Nature Reviews Drug Discovery 6:8, pages 636-649.
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C. Sernia, H. Huang, K. Nguyuen, Y-H. Li, S. Hsu, M. Chen, N. Yu & M. Forwood. 2007. Frontiers in Research of the Renin-Angiotensin System on Human Disease. Frontiers in Research of the Renin-Angiotensin System on Human Disease 179 195 .

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