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Review Article

Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization

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Pages 659-678 | Received 31 Dec 2008, Accepted 05 Jul 2009, Published online: 11 Sep 2009

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Crossref
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Crossref
Masahiko Kushida, Tomoya Yamada & Yasuyoshi Okuno. 2016. Thresholds of Genotoxic Carcinogens. Thresholds of Genotoxic Carcinogens 193 203 .
T. Kobets & G.M. Williams. 2016. Thresholds of Genotoxic Carcinogens. Thresholds of Genotoxic Carcinogens 19 36 .
Neeraja K. Erraguntla & Roberta L. Grant. (2015) Health- and vegetative-based effect screening values for ethylene. Chemico-Biological Interactions 241, pages 87-93.
Crossref
James T. MacGregor, Roland Frötschl, Paul A. White, Kenny S. Crump, David A. Eastmond, Shoji Fukushima, Melanie Guérard, Makoto Hayashi, Lya G. Soeteman-Hernández, George E. Johnson, Toshio Kasamatsu, Dan D. Levy, Takeshi Morita, Lutz Müller, Rita Schoeny, Maik J. Schuler & Véronique Thybaud. (2015) IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, pages 66-78.
Crossref
Kimiko Tomioka, Kenji Obayashi, Keigo Saeki, Nozomi Okamoto & Norio Kurumatani. (2014) Increased risk of lung cancer associated with occupational exposure to benzidine and/or beta-naphthylamine. International Archives of Occupational and Environmental Health 88:4, pages 455-465.
Crossref
Byeong Hwa Yun, Viktoriya S. Sidorenko, Thomas A. Rosenquist, Kathleen G. Dickman, Arthur P. Grollman & Robert J. Turesky. (2015) New approaches for biomonitoring exposure to the human carcinogen aristolochic acid. Toxicology Research 4:4, pages 763-776.
Crossref
Kimiko Tomioka, Keigo Saeki, Kenji Obayashi, Yuu Tanaka & Norio Kurumatani. (2014) Risk for lung cancer in workers exposed to benzidine and/or beta-naphthylamine: a protocol for systematic review and meta-analysis. Systematic Reviews 3:1.
Crossref
Jennilee M.A. Gavina, Chunhe Yao & Yong-Lai Feng. (2014) Recent developments in DNA adduct analysis by mass spectrometry: A tool for exposure biomonitoring and identification of hazard for environmental pollutants. Talanta 130, pages 475-494.
Crossref
Byeong Hwa Yun, Lihua Yao, Bojan Jelaković, Jovan Nikolić, Kathleen G. Dickman, Arthur P. Grollman, Thomas A. Rosenquist & Robert J. Turesky. (2014) Formalin-fixed paraffin-embedded tissue as a source for quantitation of carcinogen DNA adducts: aristolochic acid as a prototype carcinogen. Carcinogenesis 35:9, pages 2055-2061.
Crossref
L.F. LI, R.L.Y. CHAN, L. LU, J. SHEN, L. ZHANG, W.K.K. WU, L. WANG, T. HU, M.X. LI & C.H. CHO. (2014) Cigarette smoking and gastrointestinal diseases: The causal relationship and underlying molecular mechanisms (Review). International Journal of Molecular Medicine 34:2, pages 372-380.
Crossref
Ted Simon. 2014. Environmental Risk Assessment. Environmental Risk Assessment 49 88 .
Hauh-Jyun Candy Chen & Chin-Ron Lee. (2014) Detection and simultaneous quantification of three smoking-related ethylthymidine adducts in human salivary DNA by liquid chromatography tandem mass spectrometry. Toxicology Letters 224:1, pages 101-107.
Crossref
. 2014. Essential Oil Safety. Essential Oil Safety 677 755 .
Robert Tisserand & Rodney Young. 2014. Essential Oil Safety. Essential Oil Safety 165 186 .
Errol Zeiger. 2013. Reducing, Refining and Replacing the Use of Animals in Toxicity Testing. Reducing, Refining and Replacing the Use of Animals in Toxicity Testing 311 329 .
Gwendoline Nauwelaërs, Medjda Bellamri, Valérie Fessard, Robert J. Turesky & Sophie Langouët. (2013) DNA Adducts of the Tobacco Carcinogens 2-Amino-9 H -pyrido[2,3- b ]indole and 4-Aminobiphenyl Are Formed at Environmental Exposure Levels and Persist in Human Hepatocytes . Chemical Research in Toxicology 26:9, pages 1367-1377.
Crossref
Yijin Tang, Fekadu Kassie, Xuemin Qian, Buzayew Ansha & Robert J. Turesky. (2013) DNA Adduct Formation of 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline in Mouse Liver and Extrahepatic Tissues During a Subchronic Feeding Study. Toxicological Sciences 133:2, pages 248-258.
Crossref
Byeong Hwa Yun, Thomas A. Rosenquist, Jovan Nikolić, Dejan Dragičević, Karla Tomić, Bojan Jelaković, Kathleen G. Dickman, Arthur P. Grollman & Robert J. Turesky. (2013) Human Formalin-Fixed Paraffin-Embedded Tissues: An Untapped Specimen for Biomonitoring of Carcinogen DNA Adducts by Mass Spectrometry. Analytical Chemistry 85:9, pages 4251-4258.
Crossref
Lijuan Peng & Robert J. Turesky. (2012) Capturing Labile Sulfenamide and Sulfinamide Serum Albumin Adducts of Carcinogenic Arylamines by Chemical Oxidation. Analytical Chemistry 85:2, pages 1065-1072.
Crossref
Stephen K. Durham & James A. Swenberg. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology 989 997 .
Lijuan Peng, Surendra Dasari, David L. Tabb & Robert J. Turesky. (2012) Mapping Serum Albumin Adducts of the Food-Borne Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine by Data-Dependent Tandem Mass Spectrometry . Chemical Research in Toxicology 25:10, pages 2179-2193.
Crossref
Lynn H. Pottenger, Darrell R. Boverhof & John M. WaechterJr.Jr.. 2003. Patty's Toxicology. Patty's Toxicology 425 490 .
Byeong Hwa Yun, Thomas A. Rosenquist, Viktoriya Sidorenko, Charles R. Iden, Chung-Hsin Chen, Yeong-Shiau Pu, Radha Bonala, Francis Johnson, Kathleen G. Dickman, Arthur P. Grollman & Robert J. Turesky. (2012) Biomonitoring of Aristolactam-DNA Adducts in Human Tissues Using Ultra-Performance Liquid Chromatography/Ion-Trap Mass Spectrometry. Chemical Research in Toxicology 25:5, pages 1119-1131.
Crossref
Bojan Jelaković, Sandra Karanović, Ivana Vuković-Lela, Frederick Miller, Karen L. Edwards, Jovan Nikolić, Karla Tomić, Neda Slade, Branko Brdar, Robert J. Turesky, Želimir Stipančić, Damir Dittrich, Arthur P. Grollman & Kathleen G. Dickman. (2012) Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid. Kidney International 81:6, pages 559-567.
Crossref
A. Paini, G. Scholz, M. Marin-Kuan, B. Schilter, J. O'Brien, P. J. van Bladeren & I. M. C. M. Rietjens. (2011) Quantitative comparison between in vivo DNA adduct formation from exposure to selected DNA-reactive carcinogens, natural background levels of DNA adduct formation and tumour incidence in rodent bioassays. Mutagenesis 26:5, pages 605-618.
Crossref
Robert J. Turesky & Loic Le Marchand. (2011) Metabolism and Biomarkers of Heterocyclic Aromatic Amines in Molecular Epidemiology Studies: Lessons Learned from Aromatic Amines. Chemical Research in Toxicology 24:8, pages 1169-1214.
Crossref
Robert Nilsson. (2011) The molecular basis for induction of human cancers by tobacco specific nitrosamines. Regulatory Toxicology and Pharmacology 60:2, pages 268-280.
Crossref
Gwendoline Nauwelaers, Erin E. Bessette, Dan Gu, Yijin Tang, Julie Rageul, Valérie Fessard, Jian-Min Yuan, Mimi C. Yu, Sophie Langouët & Robert J. Turesky. (2011) DNA Adduct Formation of 4-Aminobiphenyl and Heterocyclic Aromatic Amines in Human Hepatocytes. Chemical Research in Toxicology 24:6, pages 913-925.
Crossref
Anthony M. Lynch, Jennifer C. Sasaki, Rosalie Elespuru, David Jacobson-Kram, Véronique Thybaud, Marlies De Boeck, Marilyn J. Aardema, Jiri Aubrecht, R. Daniel Benz, Stephen D. Dertinger, George R. Douglas, Paul A. White, Patricia A. Escobar, Albert FornaceJr.Jr., Masamitsu Honma, Russell T. Naven, James F. Rusling, Robert H. Schiestl, Richard M. Walmsley, Eiji Yamamura, Jan van Benthem & James H. Kim. (2011) New and emerging technologies for genetic toxicity testing. Environmental and Molecular Mutagenesis 52:3, pages 205-223.
Crossref
J. A. Swenberg, K. Lu, B. C. Moeller, L. Gao, P. B. Upton, J. Nakamura & T. B. Starr. (2010) Endogenous versus Exogenous DNA Adducts: Their Role in Carcinogenesis, Epidemiology, and Risk Assessment. Toxicological Sciences 120:Supplement 1, pages S130-S145.
Crossref
Ilona Silins & Johan Högberg. (2011) Combined Toxic Exposures and Human Health: Biomarkers of Exposure and Effect. International Journal of Environmental Research and Public Health 8:3, pages 629-647.
Crossref
M. Marin-Kuan, V. Ehrlich, T. Delatour, C. Cavin & B. Schilter. (2011) Evidence for a Role of Oxidative Stress in the Carcinogenicity of Ochratoxin A. Journal of Toxicology 2011, pages 1-15.
Crossref
Chad M. Thompson, Laurie C. Haws, Mark A. Harris, Nicole M. Gatto & Deborah M. Proctor. (2011) Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium. Toxicological Sciences 119:1, pages 20-40.
Crossref
Lynn H. Pottenger & B. Bhaskar Gollapudi. (2010) Genotoxicity testing: Moving beyond qualitative “screen and bin” approach towards characterization of dose‐response and thresholds. Environmental and Molecular Mutagenesis 51:8-9, pages 792-799.
Crossref
Barbara L. Parsons, Meagan B. Myers, Fanxue Meng, Yiying Wang & Page B. McKinzie. (2010) Oncomutations as biomarkers of cancer risk. Environmental and Molecular Mutagenesis 51:8-9, pages 836-850.
Crossref
Erin E. BessetteSimon D. SpivackAngela K. GoodenoughTao WangShailesh PintoFred F. KadlubarRobert J. Turesky. (2010) Identification of Carcinogen DNA Adducts in Human Saliva by Linear Quadrupole Ion Trap/Multistage Tandem Mass Spectrometry. Chemical Research in Toxicology 23:7, pages 1234-1244.
Crossref
Bo Hang. (2010) Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts. Journal of Nucleic Acids 2010, pages 1-29.
Crossref
Diane Benford, P. Michael Bolger, Philip Carthew, Myriam Coulet, Michael DiNovi, Jean-Charles Leblanc, Andrew G. Renwick, Woodrow Setzer, Josef Schlatter, Benjamin Smith, Wout Slob, Gary Williams & Tanja Wildemann. (2010) Application of the Margin of Exposure (MOE) approach to substances in food that are genotoxic and carcinogenic. Food and Chemical Toxicology 48, pages S2-S24.
Crossref

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