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Critical Reviews in Toxicology Volume 49, 2019 - Issue 8
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Review Articles

Tramadol and the occurrence of seizures: a systematic review and meta-analysis

Samaneh NakhaeeMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences (BUMS), Birjand, Iran; ORCID Iconhttp://orcid.org/0000-0003-3422-6799
ORCID Icon,
Alireza AmirabadizadehMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences (BUMS), Birjand, Iran; ORCID Iconhttp://orcid.org/0000-0002-2495-5042
ORCID Icon,
Jeffrey BrentUniversity of Colorado, School of Medicine, Aurora, CO, USA; ORCID Iconhttp://orcid.org/0000-0003-3763-4755
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Ebrahim Miri-MoghaddamCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran; ORCID Iconhttp://orcid.org/0000-0001-9435-2450
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Mohsen FoadoddiniCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran; ORCID Iconhttp://orcid.org/0000-0002-9498-085X
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Khadijeh FarrokhfallMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences (BUMS), Birjand, Iran; ORCID Iconhttp://orcid.org/0000-0003-0330-4061
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Mehran HosseiniCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran; ORCID Iconhttp://orcid.org/0000-0002-6793-2035
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Mohammad AbdollahiToxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences (TUMS), Tehran, Iran; ;Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences (TUMS), Tehran, Iran; ORCID Iconhttp://orcid.org/0000-0003-0123-1209
ORCID Icon &
Omid MehrpourMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences (BUMS), Birjand, Iran; ;Rocky Mountain Poison and Drug Safety, Denver Health, Denver, CO, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-1070-8841
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Pages 710-723 | Received 09 May 2019, Accepted 15 Nov 2019, Published online: 08 Jan 2020

Citations (14)

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Wendy Cheng, Rex Pui Kin Lam & Chi Keung Chan. (2022) Factors associated with seizure in tramadol overdose: a 12-year retrospective study in Hong Kong. Clinical Toxicology 60:11, pages 1220-1226.
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Weniko Caré, Alexane Tangre, Laurène Dufayet, Béranger Lekens, Hervé Laborde-Casterot, Jérôme Langrand, Bruno Mégarbane & Dominique Vodovar. (2022) Exposure to immediate-release tramadol in children 6 years and under – a nationwide French poison control center study. Clinical Toxicology 60:6, pages 750-758.
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Akhona Fynn, Elvera Helberg, Brian Godman & Johanna C Meyer. (2020) Drug utilization review of tramadol hydrochloride in a regional hospital in South Africa; findings and implications. Hospital Practice 48:2, pages 92-99.
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Articles from other publishers (11)

Alireza Amanollahi, Yadollah Mehrabi, Mohsen Sedighi, Hamed Basir Ghafouri, Amir Zahedi, Shahin Shadnia & Koorosh Etemad. (2023) Assessment of renal function indexes in methamphetamine or tramadol intoxication adults to the emergency departments: a systematic review and meta-analysis. BMC Emergency Medicine 23:1.
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Farhad Iranmanesh, Hamide Arvan, Habibeh Ahmadipour, Faranak Gadari, Hussien Barzegar & Mahdiyeh Khazaneha. (2023) Tramadol Abuse-associated Seizure: An Epidemiological and Electroencephalographic Study. International Journal of High Risk Behaviors and Addiction 11:4.
Crossref
Camille Lagard, Dominique Vodovar, Lucie Chevillard, Jacques Callebert, Fabien Caillé, Géraldine Pottier, Hao Liang, Patricia Risède, Nicolas Tournier & Bruno Mégarbane. (2022) Investigation of the Mechanisms of Tramadol-Induced Seizures in Overdose in the Rat. Pharmaceuticals 15:10, pages 1254.
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Sohee Park, Hyesung Lee, Ju Hwan Kim, Ha‐Lim Jeon & Ju‐Young Shin. (2022) Association between tramadol use and seizures: A nationwide case–case‐time‐control study. Pharmacoepidemiology and Drug Safety 31:6, pages 614-622.
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Daniel G. Tobin, Mark B. Lockwood, Paul L. Kimmel, Laura M. Dember, Nwamaka D. Eneanya, Manisha Jhamb, Thomas D. Nolin, William C. Becker & Michael J. Fischer. (2021) Opioids for chronic pain management in patients with dialysis-dependent kidney failure. Nature Reviews Nephrology 18:2, pages 113-128.
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Samaneh Nakhaee, Khadijeh Farrokhfall, Ebrahim Miri-Moghaddam, Masoumeh Askari, Alireza Amirabadizadeh, Mohsen Foadoddini & Omid Mehrpour. (2021) Effects of naloxone and diazepam on blood glucose levels in tramadol overdose using generalized estimating equation (GEE) model; (an experimental study). BMC Endocrine Disorders 21:1.
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Monisha Seralathan, Gaurav Kumar Singh, Sudheendra Huddar, Leo Mathew, Arun Kandasamy & Jayant Mahadevan. (2021) Intravenous tapentadol use related seizures – A Case Report. Asian Journal of Psychiatry 66, pages 102911.
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Marwa H. Bakr, Eman Radwan, Asmaa S. Shaltout, Alshaimaa A. Farrag, Amany Refaat Mahmoud, Tarek Hamdy Abd-Elhamid & Maha Ali. (2021) Chronic exposure to tramadol induces cardiac inflammation and endothelial dysfunction in mice. Scientific Reports 11:1.
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Samaneh Nakhaee, Christopher Hoyte, Richard C. Dart, Masoumeh Askari, Roland J. Lamarine & Omid Mehrpour. (2021) A review on tramadol toxicity: mechanism of action, clinical presentation, and treatment. Forensic Toxicology 39:2, pages 293-310.
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Samaneh Nakhaee, Khadijeh Farrokhfall, Ebrahim Miri-Moghaddam, Mohsen Foadoddini, Masoumeh Askari, Alireza Amirabadizadeh, Jeffrey Brent, Bruno Megarbane & Omid Mehrpour. (2021) The effects of naloxone, diazepam, and quercetin on seizure and sedation in acute on chronic tramadol administration: an experimental study. Behavioral and Brain Functions 17:1.
Crossref
John A. Bumpus. (2020) Low-Dose Tramadol as an Off-Label Antidepressant: A Data Mining Analysis from the Patients’ Perspective. ACS Pharmacology & Translational Science 3:6, pages 1293-1303.
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