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Review Articles

Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?

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Pages 328-358 | Received 14 Dec 2020, Accepted 26 Mar 2021, Published online: 02 Jun 2021

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Stephanie Melching-Kollmuss, Kathrin Bothe, Alex Charlton, Babunilayam Gangadharan, Rashin Ghaffari, Sylvia Jacobi, Sue Marty, Heike-Antje Marxfeld, Elizabeth F. McInnes, Ursula G. Sauer, Larry P. Sheets, Christian Strupp, Helen Tinwell, Christiane Wiemann, Philip A. Botham & Bennard van Ravenzwaay. (2023) Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS). Critical Reviews in Toxicology 53:6, pages 339-371.
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M. Sue Marty, Ursula G. Sauer, Alex Charlton, Rashin Ghaffari, Davy Guignard, Nina Hallmark, Bethany R. Hannas, Sylvia Jacobi, Heike-Antje Marxfeld, Stephanie Melching-Kollmuss, Larry P. Sheets, Daniel Urbisch, Philip A. Botham & Bennard van Ravenzwaay. (2022) Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny—part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?. Critical Reviews in Toxicology 52:7, pages 546-617.
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Articles from other publishers (2)

Christiane Wiemann, Stephanie Melching‐Kollmuss, Nina Hambruch, Lucille Wiss, Franz Stauber & Lysiane Richert. (2023) Boscalid shows increased thyroxin‐glucuronidation in rat but not in human hepatocytes in vitro. Journal of Applied Toxicology 43:6, pages 828-844.
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Mary Moxon, Stephanie Melching-Kollmuss, Giovanna Semino-Beninel & Simon Hill. (2022) The grouping of chemicals with effects on reproduction and development for the purpose of cumulative risk assessment in Europe. Reproductive Toxicology 109, pages 39-52.
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