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Leukemia & Lymphoma Volume 45, 2004 - Issue 8
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Original Article

Immunophenotypic Features of Acute Myeloid Leukemias Overexpressing the Interleukin 3 Receptor Alpha Chain

Roberta Riccioni Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, ItalyCorrespondence : [email protected]
,
Annalisa Rossini Department of Cellular Biotechnology, Istituto di Ematologia, Università “La Sapienza”, Rome, Italy
,
Luana Calabrò Cattedra e Divisione di Ematologia, Università Tor Vergata, Ospedale S. Eugenio, Rome, Italy
,
Daniela Diverio Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy
,
Luca Pasquini Department of Cellular Biotechnology, Istituto di Ematologia, Università “La Sapienza”, Rome, Italy
,
Francesco Lococo Cattedra e Divisione di Ematologia, Università Tor Vergata, Ospedale S. Eugenio, Rome, Italy
,
Cesare Peschle Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy
&
Ugo Testa Department of Cellular Biotechnology, Istituto di Ematologia, Università “La Sapienza”, Rome, Italy
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Pages 1511-1517 | Received 03 Nov 2003, Published online: 26 Aug 2009

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Fabio Guolo, Paola Minetto, Marino Clavio, Riccardo Marcolin, Maurizio Miglino, Monica Passannante, Fabrizio Caviglia, Filippo Ballerini, Elisabetta Tedone, Annalisa Kunkl, Rosa Mangerini, Paola Contini, Nicoletta Colombo, Antonia Cagnetta, Michele Cea, Enrico Carminati, Girolamo Pugliese, Marco Gobbi & Roberto Massimo Lemoli. (2020) Prognostic relevance of a blastic plasmacytoid dendritic cell neoplasm-like immunophenotype in cytogenetically normal acute myeloid leukemia patients. Leukemia & Lymphoma 61:7, pages 1695-1701.
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Tomohiro Yabushita, Hironaga Satake, Hayato Maruoka, Mari Morita, Daisuke Katoh, Yoshimitsu Shimomura, Satoshi Yoshioka, Takeshi Morimoto & Takayuki Ishikawa. (2018) Expression of multiple leukemic stem cell markers is associated with poor prognosis in de novo acute myeloid leukemia. Leukemia & Lymphoma 59:9, pages 2144-2151.
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Arthur Frankel, Jen-Sing Liu, David Rizzieri & Donna Hogge. (2008) Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia. Leukemia & Lymphoma 49:3, pages 543-553.
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Jun Liu, Xu Tan, Ying-Ying Ma, Yao Liu, Li Gao, Lei Gao, PeiYang Kong, Xian-Gui Peng, Xi Zhang & Cheng Zhang. (2019) Study on the Prognostic Value of Aberrant Antigen in Patients With Acute B Lymphocytic Leukemia. Clinical Lymphoma Myeloma and Leukemia 19:7, pages e349-e358.
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Robin E. Gasiorowski, Georgina J. Clark, Kenneth Bradstock & Derek N. J. Hart. (2014) Antibody therapy for acute myeloid leukaemia. British Journal of Haematology 164:4, pages 481-495.
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Jianbiao Zhou. (2014) Identification and targeting leukemia stem cells: The path to the cure for acute myeloid leukemia. World Journal of Stem Cells 6:4, pages 473.
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S.-R. Kuo, L. Wong & J.-S. Liu. (2012) Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells. Protein Engineering Design and Selection 25:10, pages 561-570.
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Wei DuXu-E Li, Jared SippleQishen Pang. (2011) Overexpression of IL-3Rα on CD34+CD38− stem cells defines leukemia-initiating cells in Fanconi anemia AML. Blood 117:16, pages 4243-4252.
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Roberta Riccioni, Elvira Pelosi, Viviana Riti, Germana Castelli, Francesco Lo‐Coco & Ugo Testa. (2011) Immunophenotypic features of acute myeloid leukaemia patients exhibiting high FLT3 expression not associated with mutations. British Journal of Haematology 153:1, pages 33-42.
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Angel F Lopez, Timothy R Hercus, Paul Ekert, Dene R Littler, Mark Guthridge, Daniel Thomas, Hayley S Ramshaw, Frank Stomski, Michelle Perugini, Richard D'Andrea, Michele Grimbaldeston & Michael W Parker. (2010) Molecular basis of cytokine receptor activation. IUBMB Life 62:7, pages 509-518.
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Liqing Jin, Erwin M. Lee, Hayley S. Ramshaw, Samantha J. Busfield, Armando G. Peoppl, Lucy Wilkinson, Mark A. Guthridge, Daniel Thomas, Emma F. Barry, Andrew Boyd, David P. Gearing, Gino Vairo, Angel F. Lopez, John E. Dick & Richard B. Lock. (2009) Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells. Cell Stem Cell 5:1, pages 31-42.
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