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Research Article

High Functional P-glycoprotein Activity is More Often Present in T-cell Acute Lymphoblastic Leukaemic Cells in Adults than in Children

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Pages 85-95 | Published online: 01 Jul 2009

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Soheila Rahgozar, Alireza Moafi, Marjan Abedi, Mansureh Entezar-e-ghaem, Jamal Moshtaghian, Kamran Ghaedi, Abolghasem Esmaeili & Fatemeh Montazeri. (2014) mRNA expression profile of multidrug-resistant genes in acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2. Cancer Biology & Therapy 15:1, pages 35-41.
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Ana Carolina Rabello de Moraes, Marley Aparecida Licínio, Júlio Araújo Zampirolo, Susie Coutinho Liedke, Joanita Ângela Gonzaga Del Moral, Marcos José Machado, Maria Luiza Bazzo & Maria Cláudia Santos da Silva. (2012) Evaluation of multidrug resistance in 46 newly diagnosed patients with acute leukemia. Hematology 17:2, pages 59-65.
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Arcadi I. Svirnovski, Tatsiana V. Shman, Tatsiana F. Serhiyenka, Valery P. Savitski, Victoria V. Smolnikova & Uladzimir U. Fedasenka. (2009) ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells. Hematology 14:4, pages 204-212.
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Suresh Katragadda, Balasubrahmanyam Budda, Banmeet S Anand & Ashim K Mitra. (2005) Role of efflux pumps and metabolising enzymes in drug delivery. Expert Opinion on Drug Delivery 2:4, pages 683-705.
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Alberto Grossi & Monica Biscardi. (2004) Reversal of MDR by Verapamil Analogues. Hematology 9:1, pages 47-56.
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Hanna Janiszewska, Jan Styczynski, Beata Kolodziej, Mariusz Wysocki & Olga Haus. (2009) Changes in the MDR1 gene expression after short-term ex vivo therapy with prednisolone have prognostic impact in childhood acute lymphoblastic leukemia. Annals of Hematology 88:12, pages 1193-1198.
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Frouzandeh Mahjoubi, Masoud Golalipour, Ardeshir Ghavamzadeh & Kamran Alimoghaddam. (2008) Expression of MRP1 gene in acute leukemia. Sao Paulo Medical Journal 126:3, pages 172-179.
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D Steinbach & O Legrand. (2007) ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra?. Leukemia 21:6, pages 1172-1176.
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Meyling H CheokSanne LugthartWilliam E. Evans. (2006) PHARMACOGENOMICS OF ACUTE LEUKEMIA. Annual Review of Pharmacology and Toxicology 46:1, pages 317-353.
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Katrien Swerts, Barbara De Moerloose, Catharina Dhooge, Geneviève Laureys, Yves Benoit & Jan Philippé. (2006) Prognostic significance of multidrug resistance-related proteins in childhood acute lymphoblastic leukaemia. European Journal of Cancer 42:3, pages 295-309.
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Blanca Xicoy, Josep M. Ribera, Albert Oriol, Miguel A. Sanz, Eugenia Abella, Mar Tormo, Eloy del Potro, Javier Bueno, Carlos Grande, Javier Fern?ndez-Calvo, Maribel Orts, Andr?s Novo, Concepci?n Rivas, Jes?s M. Hern?ndez-Rivas, Evarist Feliu & Juan J. Ortega. (2006) Significado pron?stico de los subtipos inmunol?gicos de la leucemia aguda linfobl?stica T del adulto. Estudio de 81 pacientes. Medicina Cl?nica 126:2, pages 41-46.
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Sabine L.A. Plasschaert, Eveline S.J.M. de Bont, Marike Boezen, Dorina M. vander Kolk, Simon M.J.G. Daenen, Klaas Nico Faber, Willem A. Kamps, Elisabeth G.E. de Vries & Edo Vellenga. (2005) Expression of Multidrug Resistance–Associated Proteins Predicts Prognosis in Childhood and Adult Acute Lymphoblastic Leukemia. Clinical Cancer Research 11:24, pages 8661-8668.
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Tang-Her Jaing, Chao-Ping Yang, Iou-Jih Hung, Pei-Kwei Tsay, Chen-Kan Tseng & Shih-Hsiang Chen. (2005) Clinical significance of central nervous system involvement at diagnosis of childhood t-cell acute lymphoblastic leukemia. Pediatric Blood & Cancer 45:2, pages 135-138.
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Sabine L.A Plasschaert, Willem A Kamps, Edo Vellenga, Elisabeth G.E de Vries & Eveline S.J.M de Bont. (2004) Prognosis in childhood and adult acute lymphoblastic leukaemia: a question of maturation?. Cancer Treatment Reviews 30:1, pages 37-51.
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Elvis Terci Valera, Carlos Alberto Scrideli, Rosane Gomes de Paula Queiroz, Bianca Maria Ortelli Mori & Luiz Gonzaga Tone. (2004) Multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) gene expression in childhood acute lymphoblastic leukemia. Sao Paulo Medical Journal 122:4, pages 166-171.
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Gary D Kruh & Martin G Belinsky. (2003) The MRP family of drug efflux pumps. Oncogene 22:47, pages 7537-7552.
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