Advanced search
Publication Cover
Leukemia & Lymphoma Volume 43, 2002 - Issue 5
Submit an article Journal homepage
22
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Treatment of Refractory Acute Leukemia with Timed Sequential Chemotherapy Using Topotecan Followed by Etoposide+Mitoxantrone (T-EM) and Correlation with Topoisomerase II Levels

M.G. Mainwaring University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
L.M. Rimsza Department of Pathology, Division of Hematopathology, Gainesville, FL, USA
,
S.F. Chen Malcolm Randall (Gainesville), VA Medical Center Research Service, Gainesville, FL, USA
,
S.P. Gomez Malcolm Randall (Gainesville), VA Medical Center Research Service, Gainesville, FL, USA
,
F.W. Weeks Vero Beach Oncology, Vero Beach, FL 32964, USA
,
V. Reddy University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
J. Lynch University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
W.S. May University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
S. Kahn University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
J. Moreb University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
H. Leather University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
,
R. Braylan Department of Pathology, Division of Hematopathology, Gainesville, FL, USA
,
T.C. Rowe Department of Pharmacology, Gainesville, FL 32610, USA
,
K.J. Finiewicz University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
&
J.R. Wingard University of Florida College of Medicine, Division of Hematology/Oncology, Gainesville, FL, USA
 show all
Pages 989-999 | Published online: 01 Jul 2009

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Azra Raza, Laurie Lisak, Jennifer Billmeier, Hassan Pervaiz, Muhammad Mumtaz, Samreen Gohar, Khalid Wahid & Naomi Galili. (2006) Phase II study of topotecan and thalidomide in patients with high-risk myelodysplastic syndromes. Leukemia & Lymphoma 47:3, pages 433-440.
Read now
Ladislav Novotny & Thomas Szekeres. (2003) Cancer Therapy: New Targets for Chemotherapy. Hematology 8:3, pages 129-137.
Read now

Articles from other publishers (9)

Laura W. Goff, Mace L. Rothenberg, A Craig Lockhart, Bruce J. Roth, Wendy L. VerMeulen, Emily Chan & Jordan D. Berlin. (2008) A Phase I Trial of Irinotecan Alternating With Epirubicin in Patients With Advanced Malignancies. American Journal of Clinical Oncology 31:5, pages 413-416.
Crossref
Biren Saraiya, Murugesan Gounder, Jayeeta Dutta, Ahamed Saleem, Celeste Collazo, Luz Zimmerman, Ahamed Nazar, Mecide Gharibo, Dale Schaar, Yong Lin, Weichung Shih, Joseph Aisner, Roger K. Strair & Eric H. Rubin. (2008) Sequential topoisomerase targeting and analysis of mechanisms of resistance to topotecan in patients with acute myelogenous leukemia. Anti-Cancer Drugs 19:4, pages 411-420.
Crossref
Yaming Su, Sung-Hack Lee & Patrick J. Sinko. (2006) Inhibition of efflux transporter ABCG2/BCRP does not restore mitoxantrone sensitivity in irinotecan-selected human leukemia CPT-K5 cells: Evidence for multifactorial multidrug resistance. European Journal of Pharmaceutical Sciences 29:2, pages 102-110.
Crossref
George R. Simon, Richard M. Lush, Jana Gump, Leticia Tetteh, Charles Williams, Alan Cantor, Scott Antonia, Christopher Garrett, Caio Rocha-Lima, Mayer Fishman, Daniel M. Sullivan & Pamela N. Munster. (2006) Sequential oral 9-nitrocamptothecin and etoposide: a pharmacodynamic- and pharmacokinetic-based phase I trial. Molecular Cancer Therapeutics 5:8, pages 2130-2137.
Crossref
N C Levitt, D J Propper, S Madhusudan, J P Braybrooke, C Echeta, R te Poele, S L Davies, E Flanagan, I D Hickson, S Joel & T S Ganesan. (2005) Pharmacokinetically guided phase I trial of topotecan and etoposide phosphate in recurrent ovarian cancer. British Journal of Cancer 93:1, pages 60-69.
Crossref
Max Kreditor, Matthew Fink & Howard S. Hochster. 2005. 61 100 .
Javier Bolaños-Meade, Chuanfa Guo, Ivana Gojo & Judith E Karp. (2004) A phase II study of timed sequential therapy of acute myelogenous leukemia (AML) for patients over the age of 60: two cycle timed sequential therapy with topotecan, ara-C and mitoxantrone in adults with poor-risk AML. Leukemia Research 28:6, pages 571-577.
Crossref
E A Kolb & P G Steinherz. (2003) A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia. Leukemia 17:10, pages 1967-1972.
Crossref
. (2002) Current Awareness in Hematological Oncology. Hematological Oncology 20:4, pages 189-196.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.