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Leukemia & Lymphoma Volume 44, 2003 - Issue 11
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Research Article

The Role of DNA Hypermethylation in the Pathogenesis and Prognosis of Acute Lymphoblastic Leukemia

Jose Roman-Gomez Department of Hematology Reina Sofia Hospital 14004 Cordoba Spain
,
Juan A. Castillejo Department of Hematology Reina Sofia Hospital 14004 Cordoba Spain
,
Antonio Jimenez Department of Hematology Carlos Haya Hospital Malaga Spain
,
Manuel Barrios Department of Hematology Carlos Haya Hospital Malaga Spain
,
Anabel Heiniger Department of Hematology Carlos Haya Hospital Malaga Spain
&
Antonio Torres Department of Hematology Reina Sofia Hospital 14004 Cordoba Spain
Pages 1855-1864 | Published online: 01 Jul 2009

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Lena Harder, Ann-Christin Puller & Martin A Horstmann. (2014) ZNF423: Transcriptional modulation in development and cancer. Molecular & Cellular Oncology 1:3.
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Jose Roman-Gomez, Antonio Jimenez-Velasco, Manuel Barrios, Felipe Prosper, Anabel Heiniger, Antonio Torres & Xabier Agirre. (2007) Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes. Leukemia & Lymphoma 48:7, pages 1269-1282.
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Articles from other publishers (15)

Pablo Iglesias, Ann-Christin Puller, Marcos Seoane, Michael Spohn, Sabine Raasch, Marianne Klokow, Jürgen Müller, Lia Burkhardt, Daniela Indenbirken & Martin A. Horstmann. (2021) Genome-wide interference of ZNF423 with B-lineage transcriptional circuitries in acute lymphoblastic leukemia. Blood Advances 5:5, pages 1209-1223.
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Ezzatollah Fathi, Raheleh Farahzadi, Soheila Montazersaheb & Yasin Bagheri. (2021) Epigenetic Modifications in Acute Lymphoblastic Leukemia: From Cellular Mechanisms to Therapeutics. Current Gene Therapy 21:1, pages 60-71.
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Daeun Kim, Yerin Kim & Yuri Kim. (2019) Effects of β-carotene on Expression of Selected MicroRNAs, Histone Acetylation, and DNA Methylation in Colon Cancer Stem Cells. Journal of Cancer Prevention 24:4, pages 224-232.
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Fatemeh Memari, Zeinab Joneidi, Behnaz Taheri, Sedigheh Fekri Aval, Amir Roointan & Nosratollah Zarghami. (2018) Epigenetics and Epi-miRNAs: Potential markers/therapeutics in leukemia. Biomedicine & Pharmacotherapy 106, pages 1668-1677.
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Michael J. Burke & Teena Bhatla. (2014) Epigenetic Modifications in Pediatric Acute Lymphoblastic Leukemia. Frontiers in Pediatrics 2.
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Brian L Burnette, Mrinal S Patnaik & Mark R Litzow. (2012) Pharmacotherapy for adult acute lymphoblastic leukemia: an update from recent clinical trials and future directions. Clinical Investigation 2:7, pages 715-731.
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Eman Abdel Rahman Ismail, Mahira Ismail El-Mogy, Deena Samir Mohamed & Rania Ali Hassan El-Farrash. (2011) Methylation Pattern of Calcitonin (CALCA) Gene in Pediatric Acute Leukemia. Journal of Pediatric Hematology/Oncology 33:7, pages 534-542.
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Ioannis S. Vizirianakis, Maria Chatzopoulou, Ioannis D. Bonovolias, Ioannis Nicolaou, Vassilis J. Demopoulos & Asterios S. Tsiftsoglou. (2010) Toward the Development of Innovative Bifunctional Agents To Induce Differentiation and To Promote Apoptosis in Leukemia: Clinical Candidates and Perspectives. Journal of Medicinal Chemistry 53:19, pages 6779-6810.
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Lisa A Cowan, Sundeep Talwar & Allen S Yang. (2010) Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors. Epigenomics 2:1, pages 71-86.
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Dominique J. P. M. StumpelPauline SchneiderEddy H. J. van Roon, Judith M. Boer, Paola de Lorenzo, Maria G. Valsecchi, Renee X. de Menezes, Rob PietersRonald W. Stam. (2009) Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options. Blood 114:27, pages 5490-5498.
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Hoenil Jo, Sokbom Kang, Jae W. Kim, Gyeong H. Kang, Noh H. Park, Yong S. Song, Sang Y. Park, Soon B. Kang & Hyo P. Lee. (2007) Hypermethylation of the COX-2 gene is a potential prognostic marker for cervical cancer. Journal of Obstetrics and Gynaecology Research 33:3, pages 236-241.
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Kristen H. Taylor, Keila E. Pena-Hernandez, J. Wade Davis, Gerald L. Arthur, Deiter J. Duff, Huidong Shi, Farah B. Rahmatpanah, Ozy Sjahputera & Charles W. Caldwell. (2007) Large-Scale CpG Methylation Analysis Identifies Novel Candidate Genes and Reveals Methylation Hotspots in Acute Lymphoblastic Leukemia. Cancer Research 67:6, pages 2617-2625.
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Kirsteen H. Maclean & John L. Cleveland. 2010. Childhood Leukemias. Childhood Leukemias 339 361 .
J Roman-Gomez, A Jimenez-Velasco, X Agirre, J A Castillejo, G Navarro, M Barrios, E J Andreu, F Prosper, A Heiniger & A Torres. (2004) Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia. British Journal of Cancer 91:4, pages 707-713.
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. (2004) Current Awareness in Hematological Oncology. Hematological Oncology 22:2, pages 73-84.
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