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Original Article

Monoclonal Antibodies in the Treatment of Chronic Lymphoid Leukemias

Pages 205-219 | Received 25 Apr 2003, Published online: 03 Aug 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Tadeusz Robak. (2008) Alemtuzumab for B-cell chronic lymphocytic leukemia. Expert Review of Anticancer Therapy 8:7, pages 1033-1051.
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Tadeusz Robak. (2008) Emerging drugs for rarer chronic lymphoid leukemias. Expert Opinion on Emerging Drugs 13:1, pages 95-118.
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Mohamed A Kharfan-Dabaja, Rabih Fahed, Mohamad Hussein & Edgardo S Santos. (2007) Evolving role of monoclonal antibodies in the treatment of chronic lymphocytic leukemia. Expert Opinion on Investigational Drugs 16:11, pages 1799-1815.
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Ewa Robak & Tadeusz Robak. (2007) Skin lesions in chronic lymphocytic leukemia. Leukemia & Lymphoma 48:5, pages 855-865.
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Paweł Robak, Anna Linke, Barbara Cebula, Tadeusz Robak & Piotr Smolewski. (2006) Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells. Leukemia & Lymphoma 47:12, pages 2625-2634.
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Suneel Mundle & Yelina Noskina. (2005) Cytogenetic testing for therapeutic indication in cancer. Expert Review of Molecular Diagnostics 5:1, pages 23-29.
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Piotr Smolewski, Anna Szmigielska-Kaplon, Barbara Cebula, Krzysztof Jamroziak, Małgorzata Rogalinska, Zofia Kilianska & Tadeusz Robak. (2005) Proapoptotic activity of alemtuzumab alone and in combination with rituximab or purine nucleoside analogues in chronic lymphocytic leukemia cells. Leukemia & Lymphoma 46:1, pages 87-100.
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Articles from other publishers (34)

Rohan G. Shinde, Vipul P. Patel, Shwetarani D. Gundgole, Suchita S. Dhumale & Snehal D. Dhole. (2022) A Current Review of Systemic Lupus Erythematosus Treatment Using Monoclonal Antibodies. Current Biotechnology 11:1, pages 27-31.
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Naval Daver, Aziz Nazha, Hagop M. Kantarjian, Rodney Haltom & Farhad Ravandi. (2013) Treatment of Hairy Cell Leukemia During Pregnancy: Are Purine Analogues and Rituximab Viable Therapeutic Options. Clinical Lymphoma Myeloma and Leukemia 13:1, pages 86-89.
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Tadeusz Robak. (2013) Emerging monoclonal antibodies and related agents for the treatment of chronic lymphocytic leukemia. Future Oncology 9:1, pages 69-91.
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Neerav Shukla, Rachel Kobos, Thomas Renaud, Julie Teruya‐Feldstein, Anita Price, Linda McAllister‐Lucas & Peter Steinherz. (2011) Successful treatment of refractory metastatic histiocytic sarcoma with alemtuzumab. Cancer 118:15, pages 3719-3724.
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Nermeen Ahmed El DesoukeyReham Abd Aleem AfifyDalia Gamil AminRasha Faragaly Mohammed. (2023) CD200 Expression in B-Cell Chronic Lymphoproliferative Disorders. Journal of Investigative Medicine 60:1, pages 56-61.
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I. García-Escobar, J. Sepúlveda, D. Castellano & H. Cortés-Funes. (2011) Therapeutic management of chronic lymphocytic leukaemia. Critical Reviews in Oncology/Hematology 80:1, pages 100-113.
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Tim Illidge & Franck Morschhauser. (2011) Radioimmunotherapy in follicular lymphoma. Best Practice & Research Clinical Haematology 24:2, pages 279-293.
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Tadeusz Robak. (2011) Hairy-cell leukemia variant: Recent view on diagnosis, biology and treatment. Cancer Treatment Reviews 37:1, pages 3-10.
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Holly M. Horton, Matthew J. Bernett, Matthias Peipp, Erik Pong, Sher Karki, Seung Y. Chu, John O. Richards, Hsing Chen, Roland Repp, John R. Desjarlais & Eugene A. Zhukovsky. (2010) Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies. Blood 116:16, pages 3004-3012.
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Y. Uzunhan, J. Cadranel, N. Boissel, C. Gardin, B. Arnulf & A. Bergeron. (2010) Les manifestations pulmonaires spécifiques des hémopathies myéloïdes aiguës et des hémopathies lymphoïdes et lymphoplasmocytaires. Partie II : les manifestations pulmonaires spécifiques des hémopathies lymphoïdes et lymphoplasmocytaires (hors lymphomes). Revue des Maladies Respiratoires 27:6, pages 599-610.
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Carlos Cassano, Swetlana Mactier, Stephen P. Mulligan, Larissa Belov, Pauline Huang & Richard I. Christopherson. (2010) Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders. International Journal of Proteomics 2010, pages 1-9.
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Andrei Ivanov, Ruth Swann & Tim Illidge. (2008) New insights into the mechanisms of action of radioimmunotherapy in lymphoma. Journal of Pharmacy and Pharmacology 60:8, pages 987-998.
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Tadeusz Robak, Krzysztof Jamroziak & Pawel Robak. (2009) Current and Emerging Treatments for Chronic Lymphocytic Leukaemia. Drugs 69:17, pages 2415-2449.
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Anne L. Angiolillo, Alice L. Yu, Gregory Reaman, Ashish M. Ingle, Rita Secola & Peter C. Adamson. (2009) A phase II study of Campath‐1H in children with relapsed or refractory acute lymphoblastic leukemia: A Children's Oncology Group report. Pediatric Blood & Cancer 53:6, pages 978-983.
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Tadeusz Robak. (2009) Ofatumumab for the treatment of chronic lymphocytic leukemia. Therapy 6:4, pages 577-587.
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Sara Huerta-Yepez, Mario Vega, Saul E. Escoto-Chavez, Benjamin Murdock, Toshiyuki Sakai, Stavroula Baritaki & Benjamin Bonavida. (2009) Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 1. Nitric Oxide 20:1, pages 39-52.
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Thomas Elter, Janne J. Vehreschild, John Gribben, Oliver A. Cornely, Andreas Engert & Michael Hallek. (2008) Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab. Annals of Hematology 88:2, pages 121-132.
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Roger S. Riley, David Williams, Micaela Ross, Shawn Zhao, Alden Chesney, Bradly D. Clark & Jonathan M. Ben‐Ezra. (2009) Bone marrow aspirate and biopsy: a pathologist's perspective. II. interpretation of the bone marrow aspirate and biopsy. Journal of Clinical Laboratory Analysis 23:5, pages 259-307.
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Tadeusz Robak. (2008) Treatment of chronic lymphoid leukemias with monoclonal antibodies: current place and perspectives. Drug Development Research 69:7, pages 373-387.
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Tim IllidgeMike Bayne. 2008. Treatment of Cancer Fifth Edition. Treatment of Cancer Fifth Edition 203 225 .
Tadeusz Robak. (2007) Recent progress in the management of chronic lymphocytic leukemia. Cancer Treatment Reviews 33:8, pages 710-728.
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Tadeusz Robak, Piotr Smolewski, Barbara Cebula, Olga Grzybowska-Izydorczyk & Jerzy Z. Błoński. (2007) Rituximab plus cladribine with or without cyclophosphamide in patients with relapsed or refractory chronic lymphocytic leukemia. European Journal of Haematology 79:2, pages 107-113.
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A. Süß, T. Wetzig, M. Sticherling, A. Tannapfel & J. C. Simon. (2006) Mycosis fungoides und chronisch lymphatische B-Zell-LeukämieMycosis fungoides and B-cell chronic lymphocytic leukemia. Der Hautarzt 57:10, pages 888-892.
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Tadeusz Robak, Piotr Smolewski, Barbara Cebula, Anna Szmigielska‐Kaplon, Krzysztof Chojnowski & Jerzy Z. Blonski. (2006) Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma. Cancer 107:7, pages 1542-1550.
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Elaine J. Coleman, Kimberly J. Brooks, Joan E. Smallshaw & Ellen S. Vitetta. (2006) The Fc Portion of UV3, an Anti-CD54 Monoclonal Antibody, Is Critical for its Antitumor Activity in SCID Mice With Human Multiple Myeloma or Lymphoma Cell Lines. Journal of Immunotherapy 29:5, pages 489-498.
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Livio PaganoMorena CairaLuana FianchiGiuseppe Leone. (2006) Acute lymphoblastic leukemia in elderly patients: clinical characteristics, treatment and outcome. Aging Health 2:1, pages 123-133.
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John R. McWhirter, Anke Kretz-Rommel, Alan Saven, Toshiaki Maruyama, Kathleen N. Potter, C. Ian Mockridge, E. Prenn Ravey, Fenghua Qin & Katherine S. Bowdish. (2006) Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation. Proceedings of the National Academy of Sciences 103:4, pages 1041-1046.
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Che-Leung Law, Kristine A. Gordon, John Collier, Kerry Klussman, Julie A. McEarchern, Charles G. Cerveny, Bruce J. Mixan, Wyne P. Lee, Zhonghau Lin, Patricia Valdez, Alan F. Wahl & Iqbal S. Grewal. (2005) Preclinical Antilymphoma Activity of a Humanized Anti-CD40 Monoclonal Antibody, SGN-40. Cancer Research 65:18, pages 8331-8338.
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Janice MY Brown. (2005) Exogenous administration of immunomodulatory therapies in hematopoietic cell transplantation: an infectious diseases perspective. Current Opinion in Infectious Diseases 18:4, pages 352-358.
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Tadeusz Robak. (2005) Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies. Transfusion and Apheresis Science 32:1, pages 33-44.
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Tadeusz Robak. (2005) Alemtuzumab in the Treatment of Chronic Lymphocytic Leukemia. BioDrugs 19:1, pages 9-22.
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Tadeusz Robak. (2005) Rituximab Plus Purine Nucleoside Analogs in the Treatment of Indolent Lymphoid Malignancies. American Journal of Cancer 4:5, pages 279-292.
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Tadeusz Robak. (2004) Monoclonal antibodies in the treatment of autoimmune cytopenias. European Journal of Haematology 72:2, pages 79-88.
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Tadeusz Robak. (2004) Acute Lymphoblastic Leukaemia in Elderly Patients. Drugs & Aging 21:12, pages 779-791.
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