59
Views
32
CrossRef citations to date
0
Altmetric
Review

VH3-21 Gene Usage in Chronic Lymphocytic Leukemia – Characterization of a New Subgroup with Distinct Molecular Features and Poor Survival

, , &
Pages 221-228 | Received 03 May 2003, Published online: 03 Aug 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Sergio Bianchi, Pilar Moreno, Ana Inés Landoni, Hugo Naya, Pablo Oppezzo, Guillermo Dighiero, Raúl Gabús & Otto Pritsch. (2010) Immunoglobulin heavy chain V-D-J gene rearrangement and mutational status in Uruguayan patients with chronic lymphocytic leukemia. Leukemia & Lymphoma 51:11, pages 2070-2078.
Read now
Nadiia Bilous, Riccardo Bomben, Michele Dal Bo, Daniela Capello, Francesco Forconi, Luca Laurenti, Francesco Bertoni, Dimitar G. Efremov, Roberto Marasca, Giovanni Del Poeta, Zoya Martina, Iryna Kryachouk, Iryna Dyagil, Gianluca Gaidano, Anatoliy Chumak, Valter Gattei & Iryna Abramenko. (2010) Molecular and clinical features of chronic lymphocytic leukemia with stereotyped B-cell receptors in a Ukrainian cohort. Leukemia & Lymphoma 51:5, pages 822-838.
Read now
Tom Butler & John G Gribben. (2008) Biologic prognostic markers and their application in clinical trials and management of chronic lymphocytic leukaemia patients. Expert Opinion on Medical Diagnostics 2:1, pages 101-112.
Read now
Leeona Galligan, Mark A. Catherwood, Christine Matthews, T. C. M ‘Curly' Morris & H Dennis Alexander. (2008) Mutated IgHV1-69 gene usage represents a distinct subgroup associated with indolent disease in chronic lymphocytic leukemia. Leukemia & Lymphoma 49:4, pages 763-768.
Read now
Suneel Mundle & Yelina Noskina. (2005) Cytogenetic testing for therapeutic indication in cancer. Expert Review of Molecular Diagnostics 5:1, pages 23-29.
Read now

Articles from other publishers (27)

Suliman A. Alsagaby, Paul Brennan & Chris Pepper. (2016) Key Molecular Drivers of Chronic Lymphocytic Leukemia. Clinical Lymphoma Myeloma and Leukemia 16:11, pages 593-606.
Crossref
Carole J. Henry Dunand & Patrick C. Wilson. (2015) Restricted, canonical, stereotyped and convergent immunoglobulin responses. Philosophical Transactions of the Royal Society B: Biological Sciences 370:1676, pages 20140238.
Crossref
C Pepper, A G S Buggins, C H Jones, E J Walsby, F Forconi, G Pratt, S Devereux, F K Stevenson & C Fegan. (2014) Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition. Leukemia 29:3, pages 744-747.
Crossref
Lesley-Ann Sutton, Andreas Agathangelidis, Chrysoula Belessi, Nikos Darzentas, Frederic Davi, Paolo Ghia, Richard Rosenquist & Kostas Stamatopoulos. (2013) Antigen selection in B-cell lymphomas?Tracing the evidence. Seminars in Cancer Biology 23:6, pages 399-409.
Crossref
M T S Bertilaccio, C Scielzo, G Simonetti, E Ten Hacken, B Apollonio, P Ghia & F Caligaris-Cappio. (2012) Xenograft models of chronic lymphocytic leukemia: problems, pitfalls and future directions. Leukemia 27:3, pages 534-540.
Crossref
Teodora Karan-Djurasevic, Vuk Palibrk, Tatjana Kostic, Vesna Spasovski, Gordana Nikcevic, Sanja Srzentic, Milica Colovic, Natasa Colovic, Ana Vidovic, Darko Antic, Biljana Mihaljevic, Sonja Pavlovic & Natasa Tosic. (2012) Mutational Status and Gene Repertoire of IGHV-IGHD-IGHJ Rearrangements in Serbian Patients With Chronic Lymphocytic Leukemia. Clinical Lymphoma Myeloma and Leukemia 12:4, pages 252-260.
Crossref
Nicola Cahill, Lesley-Ann Sutton, Mattias Jansson, Fiona Murray, Larry Mansouri, Rebeqa Gunnarsson, Fergus Ryan, Karin E. Smedby, Christian Geisler, Gunnar Juliusson & Richard Rosenquist. (2012) IGHV3-21 Gene Frequency in a Swedish Cohort of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia. Clinical Lymphoma Myeloma and Leukemia 12:3, pages 201-206.
Crossref
M. L. Sulda, B. J. Kuss, R. K. Hall, S. Bailey & P. J. Macardle. (2012) Clinical utility of molecular and flow cytometric markers in chronic lymphocytic leukaemia. Internal Medicine Journal 42:2, pages 137-146.
Crossref
Geir Tjønnfjord, Bernt Ly, Tom Johannesen, Anne Tierens, Klaus Beiske, Sverre Heim & Viggo Jønsson. (2012) Kronisk lymfatisk leukemi i Norge - insidens og prognose ved diagnosetidspunktet. Tidsskrift for Den norske legeforening 132:18, pages 2056-2059.
Crossref
Robert P. Hasserjian. 2011. Extranodal Lymphomas. Extranodal Lymphomas 341 393 .
Robert Paul Hasserjian. (2010) Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Monoclonal B-Cell Lymphocytosis. Surgical Pathology Clinics 3:4, pages 907-931.
Crossref
Lilla Cro, Andrea Ferrario, Marta Lionetti, Francesco Bertoni, Nadia Zucal N, Lucia Nobili, Sonia Fabris, Katia Todoerti, Agostino Cortelezzi, Andrea Guffanti, Maria Goldaniga, Luigi Marcheselli, Antonino Neri, Giorgio Lambertenghi‐Deliliers & Luca Baldini. (2010) The clinical and biological features of a series of immunophenotypic variant of B‐CLL. European Journal of Haematology 85:2, pages 120-129.
Crossref
Tom Butler & J.G. Gribben. (2010) Biologic and clinical significance of molecular profiling in Chronic Lymphocytic Leukemia. Blood Reviews 24:3, pages 135-141.
Crossref
Lena Rai, Anouska Casanova, Anthony V. Moorman, Sue Richards, Georgina Buck, Anthony H. Goldstone, Adele K. Fielding & Letizia Foroni. (2010) Antigen receptor gene rearrangements reflect on the heterogeneity of adult Acute Lymphoblastic Leukaemia (ALL) with implications of cell-origin of ALL subgroups â a UKALLXII study. British Journal of Haematology 148:3, pages 394-401.
Crossref
Riccardo Bomben, Michele Dal-Bo, Dania Benedetti, Daniela Capello, Francesco Forconi, Daniela Marconi, Francesco Bertoni, Rossana Maffei, Luca Laurenti, Davide Rossi, Maria Ilaria Del Principe, Fabrizio Luciano, Elisa Sozzi, Ilaria Cattarossi, Antonella Zucchetto, Francesca Maria Rossi, Pietro Bulian, Emanuele Zucca, Milena S. Nicoloso, Massimo Degan, Roberto Marasca, Dimitar G. Efremov, Giovanni Del Poeta, Gianluca Gaidano & Valter Gattei. (2010) Expression of Mutated IGHV3-23 Genes in Chronic Lymphocytic Leukemia Identifies a Disease Subset with Peculiar Clinical and Biological Features . Clinical Cancer Research 16:2, pages 620-628.
Crossref
Eric D. Hsi. (2009) The Leukemias of Mature Lymphocytes. Hematology/Oncology Clinics of North America 23:4, pages 843-871.
Crossref
I. JILANI, C. WEI, B. N. BEKELE, Z. J. ZHANG, M. KEATING, W. WIERDA, A. FERRAJOLI, Z. ESTROV, H. KANTARJIAN, S. M. O’BRIEN, F. J. GILES & M. ALBITAR. (2009) Soluble syndecan-1 (sCD138) as a prognostic factor independent of mutation status in patients with chronic lymphocytic leukemia. International Journal of Laboratory Hematology 31:1, pages 97-105.
Crossref
Riccardo Bomben, Michele Dal Bo, Daniela Capello, Francesco Forconi, Rossana Maffei, Luca Laurenti, Davide Rossi, Maria Ilaria Del Principe, Antonella Zucchetto, Francesco Bertoni, Francesca Maria Rossi, Pietro Bulian, Ilaria Cattarossi, Fiorella Ilariucci, Elisa Sozzi, Valeria Spina, Emanuele Zucca, Massimo Degan, Francesco Lauria, Giovanni Del Poeta, Dimitar G. Efremov, Roberto Marasca, Gianluca Gaidano & Valter Gattei. (2009) Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study. British Journal of Haematology 144:4, pages 492-506.
Crossref
Lijuan Chen, Yaping Zhang, Wenjuan Zheng, Yujie Wu, Chun Qiao, Lei Fan, Wei Xu & Jianyong Li. (2008) Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia. Leukemia Research 32:10, pages 1491-1498.
Crossref
Chaminda Gunawardana, Belinda Austen, Judith E. Powell, Christopher Fegan, Farooq Wandroo, Abe Jacobs, Guy Pratt & Paul Moss. (2008) South Asian chronic lymphocytic leukaemia patients have more rapid disease progression in comparison to White patients. British Journal of Haematology 142:4, pages 606-609.
Crossref
Fu Jun LiShouluan DingJicun PanMikhail A. ShakhmatovElena KashentsevaJiongru WuYufeng LiSeng-jaw SoongNicholas ChiorazziRandall S. Davis. (2008) FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia. Blood 112:1, pages 179-187.
Crossref
Christine Matthews, Mark A. Catherwood, T. C. M. Morris, Paul J. Kettle, Mary B. Drake, William S. Gilmore & H. Denis Alexander. (2006) Serum TK levels in CLL identify Binet stage A patients within biologically defined prognostic subgroups most likely to undergo disease progression. European Journal of Haematology 77:4, pages 309-317.
Crossref
Massimo Gentile, Francesca Romana Mauro, Anna Guarini & Robin Fo??. (2005) New developments in the diagnosis, prognosis and treatment of chronic lymphocytic leukemia. Current Opinion in Oncology 17:6, pages 597-604.
Crossref
Ben E de Pauw. (2005) Evolution in the treatment of hematologic malignancies. Current Opinion in Oncology 17:6, pages 593-596.
Crossref
R Bomben, M Dal Bo, A Zucchetto, E Zaina, P Nanni, P Sonego, G Del Poeta, M Degan & V Gattei. (2005) Mutational status of IgVH genes in B-cell chronic lymphocytic leukemia and prognosis: percent mutations or antigen-driven selection?. Leukemia 19:8, pages 1490-1492.
Crossref
Susann FältMats MerupGerard TobinUlf ThunbergGösta GahrtonRichard RosenquistAnders Wennborg. (2005) Distinctive gene expression pattern in VH3-21 utilizing B-cell chronic lymphocytic leukemia. Blood 106:2, pages 681-689.
Crossref
Maxime Hervé, Kai Xu, Yen-Shing Ng, Hedda Wardemann, Emilia Albesiano, Bradley T. Messmer, Nicholas Chiorazzi & Eric Meffre. (2005) Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity. Journal of Clinical Investigation 115:6, pages 1636-1643.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.