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Leukemia & Lymphoma Volume 45, 2004 - Issue 4
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Original Article

Derivative Chromosome 9 Deletions in Chronic Myeloid Leukemia are Associated with Loss of Tumor Suppressor Genes

Giorgina Specchia Department of Hematology, University of Bari, Bari, ItalyCorrespondence[email protected]
,
Francesco Albano Department of Hematology, University of Foggia, Foggia, Italy
,
Luisa Anelli Department of Pathologic Anathomy and Genetics, section of Genetics, University of Bari, Bari, Italy
,
Clelia Tiziana Storlazzi Department of Hematology, University of Bari, Bari, Italy
,
Antonella Zagaria Department of Hematology, University of Foggia, Foggia, Italy
,
Arcangelo Liso Department of Pathologic Anathomy and Genetics, section of Genetics, University of Bari, Bari, Italy
,
Alessandra Pannunzio Department of Hematology, University of Bari, Bari, Italy
,
Domenico Pastore Department of Hematology, University of Foggia, Foggia, Italy
,
Anna Mestice Department of Pathologic Anathomy and Genetics, section of Genetics, University of Bari, Bari, Italy
,
Giuseppina Greco Department of Hematology, University of Bari, Bari, Italy
,
Vincenzo Liso Department of Hematology, University of Foggia, Foggia, Italy
&
Mariano Rocchi Department of Pathologic Anathomy and Genetics, section of Genetics, University of Bari, Bari, Italy
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Pages 689-694 | Received 28 Aug 2003, Published online: 03 Aug 2009

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Matteo Molica, Fulvio Massaro & Massimo Breccia. (2017) Diagnostic and prognostic cytogenetics of chronic myeloid leukaemia: an update. Expert Review of Molecular Diagnostics 17:11, pages 1001-1008.
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Andrew P. Landstrom & Ayalew Tefferi. (2006) Fluorescent in situ hybridization in the diagnosis, prognosis, and treatment monitoring of chronic myeloid leukemia. Leukemia & Lymphoma 47:3, pages 397-402.
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Articles from other publishers (12)

Alvaro Andrades, Paola Peinado, Juan Carlos Alvarez-Perez, Juan Sanjuan-Hidalgo, Daniel J. García, Alberto M. Arenas, Ana M. Matia-González & Pedro P. Medina. (2023) SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities. Molecular Cancer 22:1.
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Paola Orsini, Luciana Impera, Elisa Parciante, Cosimo Cumbo, Crescenzio F. Minervini, Angela Minervini, Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Paola Casieri, Giuseppina Tota, Claudia Brunetti, Alessandra Ricco, Paola Carluccio, Giorgina Specchia & Francesco Albano. (2018) Droplet digital PCR for the quantification of Alu methylation status in hematological malignancies. Diagnostic Pathology 13:1.
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Lei Chen, Yu-Hang Zhang, Zhenghua Zhang, Tao Huang & Yu-Dong Cai. (2018) Inferring Novel Tumor Suppressor Genes with a Protein-Protein Interaction Network and Network Diffusion Algorithms. Molecular Therapy - Methods & Clinical Development 10, pages 57-67.
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Xianglan Lu, Xianfu Wang, Yougmi Kim, Rui Zhang, Shibo Li & Ji-Yun Lee. (2012) Acquired genomic copy number changes in CML patients with the Philadelphia chromosome (Ph+). Cancer Genetics 205:10, pages 513-518.
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Stefan David & Stephen J. Meltzer. 2011. Pre-Invasive Disease: Pathogenesis and Clinical Management. Pre-Invasive Disease: Pathogenesis and Clinical Management 41 63 .
Youngil Koh, Dae-Young Kim, Sung-Hyo Park, Seung-Hyun Jung, Eunkyung Park, Hyeoung-Joon Kim, Sang Kyun Sohn, Young Don Joo, Seok Jin Kim, Ho-Jin Shin, Sung-Hyun Kim, Hong Suk Song, Jooseop Chung, Inho Kim, Sung-Soo Yoon, Byoung Kook Kim, Seung-Hun Shin, Yeun-Jun Chung & Seonyang Park. (2010) GSTT1 copy number gain is a poor predictive marker for escalated-dose imatinib treatment in chronic myeloid leukemia: genetic predictive marker found using array comparative genomic hybridization. Cancer Genetics and Cytogenetics 203:2, pages 215-221.
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F Albano, L Anelli, A Zagaria, N Coccaro, P D'Addabbo, V Liso, M Rocchi & G Specchia. (2010) Genomic segmental duplications on the basis of the t(9;22) rearrangement in chronic myeloid leukemia. Oncogene 29:17, pages 2509-2516.
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Steven Richebourg, Virginie Eclache, Christine Perot, Marie-France Portnoi, Jacqueline Van den Akker, Christine Terré, Odile Maareck, Valérie Soenen, Franck Viguié, Jean-Luc Laï, Joris Andrieux, Sélim Corm & Catherine Roche-Lestienne. (2008) Mechanisms of genesis of variant translocation in chronic myeloid leukemia are not correlated with ABL1 or BCR deletion status or response to imatinib therapy. Cancer Genetics and Cytogenetics 182:2, pages 95-102.
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Sebastian KreilMarkus Pfirrmann, Claudia Haferlach, Katherine WaghornAndrew ChaseRüdiger HehlmannAndreas ReiterAndreas HochhausNicholas C. P. Cross. (2007) Heterogeneous prognostic impact of derivative chromosome 9 deletions in chronic myelogenous leukemia. Blood 110:4, pages 1283-1290.
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Francesco Albano, Luisa Anelli, Antonella Zagaria, Nicoletta Archidiacono, Vincenzo Liso, Giorgina Specchia & Mariano Rocchi. (2007) ?Home-brew? FISH assay shows higher efficiency than BCR-ABL dual color, dual fusion probe in detecting microdeletions and complex rearrangements associated with t(9;22) in chronic myeloid leukemia. Cancer Genetics and Cytogenetics 174:2, pages 121-126.
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Nathalie Douet-Guilbert, Frédéric Morel, Sylvia Quemener, Aurélie Maguer, Marie-Josée Le Bris, Patrick Morice, Christian Berthou & Marc De Braekeleer. (2006) Deletion size characterization of der(9) deletions in Philadelphia-positive chronic myeloid leukemia. Cancer Genetics and Cytogenetics 170:2, pages 89-92.
Crossref
Deborah WhiteVerity SaundersA. Bruce LyonsSusan BranfordAndrew GriggL. Bik ToTimothy Hughes. (2005) In vitro sensitivity to imatinib-induced inhibition of ABL kinase activity is predictive of molecular response in patients with de novo CML. Blood 106:7, pages 2520-2526.
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