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Research Article

AML1/ETO promotes the maintenance of early hematopoietic progenitors in NOD/SCID mice but does not abrogate their lineage specific differentiation

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Pages 265-272 | Published online: 01 Jul 2009

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K‐M. Thoms, J. Baesecke, B. Emmert, J. Hermann, T. Roedling, P. Laspe, D. Leibeling, L. Truemper & S. Emmert. (2007) Functional DNA repair system analysis in haematopoietic progenitor cells using host cell reactivation. Scandinavian Journal of Clinical and Laboratory Investigation 67:6, pages 580-588.
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D W L Chin, N Watanabe-Okochi, C Q Wang, V Tergaonkar & M Osato. (2015) Mouse models for core binding factor leukemia. Leukemia 29:10, pages 1970-1980.
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I Leskov, C P Pallasch, A Drake, B P Iliopoulou, A Souza, C-H Shen, C D Schweighofer, L Abruzzo, L P Frenzel, C M Wendtner, M T Hemann & J Chen. (2012) Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies. Oncogene 32:8, pages 1066-1072.
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Megan A. Hatlen, Lan Wang & Stephen D. Nimer. (2012) AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches. Frontiers of Medicine 6:3, pages 248-262.
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Fu-Sheng Chou, Mark Wunderlich, Andrea Griesinger & James C. Mulloy. (2011) N-RasG12D induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene. Blood 117:7, pages 2237-2240.
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A. V. Rulina, P. V. Spirin & V. S. Prassolov. (2011) Activated leukemic oncogenes AML1-ETO and c-kit: Role in development of acute myeloid leukemia and current approaches for their inhibition. Biochemistry (Moscow) 75:13, pages 1650-1666.
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D. Baskaran, P. V. Spirin & V. S. Prassolov. (2010) Activated leukemic oncogenes responsible for neoplastic transformation of hematopoietic cells. Molecular Biology 44:3, pages 369-379.
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J A Kennedy & F Barabé. (2008) Investigating human leukemogenesis: from cell lines to in vivo models of human leukemia. Leukemia 22:11, pages 2029-2040.
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Kamaleldin E. Elagib & Adam N. Goldfarb. (2007) Oncogenic pathways of AML1-ETO in acute myeloid leukemia: Multifaceted manipulation of marrow maturation. Cancer Letters 251:2, pages 179-186.
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J. A. Kennedy, F. Barabé, B. J. PattersonJ. Bayani, J. A. Squire, D. L. Barber & J. E. Dick. (2006) Expression of TEL-JAK2 in primary human hematopoietic cells drives erythropoietin-independent erythropoiesis and induces myelofibrosis in vivo . Proceedings of the National Academy of Sciences 103:45, pages 16930-16935.
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J Dunne, C Cullmann, M Ritter, N Martinez Soria, B Drescher, S Debernardi, S Skoulakis, O Hartmann, M Krause, J Krauter, A Neubauer, B D Young & O Heidenreich. (2006) siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts. Oncogene 25:45, pages 6067-6078.
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Mark WunderlichOndrej KrejciJunping WeiJames C. Mulloy. (2006) Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability. Blood 108:5, pages 1690-1697.
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Ming Yan, Eiki Kanbe, Luke F Peterson, Anita Boyapati, Yuqin Miao, Yang Wang, I-Ming Chen, Zixing Chen, Janet D Rowley, Cheryl L Willman & Dong-Er Zhang. (2006) A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis. Nature Medicine 12:8, pages 945-949.
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