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Leukemia & Lymphoma Volume 46, 2005 - Issue 4
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Original Article

Infliximab chimeric antitumor necrosis factor-α monoclonal antibody as potential treatment for myelodysplastic syndromes

Roberto Stasi Department of Medical Sciences “Regina Apostolorum” Hospital, Albano Laziale, ItalyCorrespondence[email protected]
,
Sergio Amadori Department of Haematology, University of Rome “Tor Vergata”, Italy
,
Adrian C Newland Department of Haematology, St Bartholomew's and The Royal London School of Medicine and Dentistry, London, UK
&
Drew Provan Department of Medical Sciences “Regina Apostolorum” Hospital, Albano Laziale, Italy
Pages 509-516 | Received 04 Nov 2004, Published online: 03 Aug 2009

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Rosangela Invernizzi, Erica Travaglino, Matteo Giovanni Della Porta, Luca Malcovati, Anna Gallì, Raffaella Bastia, Mariella Ciola, Ilaria Ambaglio, Emanuela Boveri, Vittorio Rosti & Mario Cazzola. (2017) Vascular endothelial growth factor overexpression in myelodysplastic syndrome bone marrow cells: biological and clinical implications. Leukemia & Lymphoma 58:7, pages 1711-1720.
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Marc Berns & Daniel W. Hommes. (2016) Anti-TNF-α therapies for the treatment of Crohn’s disease: the past, present and future. Expert Opinion on Investigational Drugs 25:2, pages 129-143.
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Lisa Pleyer & Richard Greil. (2015) Digging deep into “dirty” drugs – modulation of the methylation machinery. Drug Metabolism Reviews 47:2, pages 252-279.
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Shigeru Iwata, Kazuyoshi Saito, Kunihiro Yamaoka, Shizuyo Tsujimura, Masao Nawata, Kentaro Hanami & Yoshiya Tanaka. (2011) Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behçet’s disease. Modern Rheumatology 21:2, pages 184-191.
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Articles from other publishers (17)

Cong Wang, Yan Yang, Sujun Gao, Jingcheng Chen, Jinyuan Yu, Han Zhang, Mingxi Li, Xingying Zhan & Wei Li. (2018) Immune dysregulation in myelodysplastic syndrome: Clinical features, pathogenesis and therapeutic strategies. Critical Reviews in Oncology/Hematology 122, pages 123-132.
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Yong Chen, Yan Shen, Hai-fen Ma, Jian-Fei Cai, Yan-qin Hua, Jun Zou & Jian-long Guan. (2017) Infliximab associated with life-threatening lung infection in a patient with Behcet disease with intestinal and hematopoietic system involvement. Medicine 96:50, pages e9202.
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Arsene Mekinian, Guillaume Dervin, Nathanael Lapidus, Jean-Emmanuel Kahn, Louis Terriou, Eric Liozon, Eric Grignano, Jean-Charles Piette, Odile Beyne Rauzy, Vincent Grobost, Pascal Godmer, Jerome Gillard, Julien Rossignol, David Launay, Achille Aouba, Thierry Cardon, Laurence Bouillet, Jonathan Broner, Julien Vinit, Lionel Ades, Fabrice Carrat, Clementine Salvado, Eric Toussirot, Mathilde Versini, Nathalie Costedoat-Chalumeau, Jean Baptiste Fraison, Philippe Guilpain, Pierre Fenaux & Olivier Fain. (2017) Biologics in myelodysplastic syndrome-related systemic inflammatory and autoimmune diseases: French multicenter retrospective study of 29 patients. Autoimmunity Reviews 16:9, pages 903-910.
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Xiaoxi Zhou, Zhuoya Li & Jianfeng Zhou. (2017) Tumor necrosis factor α in the onset and progression of leukemia. Experimental Hematology 45, pages 17-26.
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Arsène Mekinian, Eric Grignano, Thorsten Braun, Olivier Decaux, Eric Liozon, Nathalie Costedoat-Chalumeau, Jean-Emmanuel Kahn, Mohammed Hamidou, Sophie Park, Xavier Puéchal, Eric Toussirot, Géraldine Falgarone, David Launay, Nathalie Morel, Sébastien Trouiller, Alexis Mathian, Bruno Gombert, Yoland Schoindre, Bertrand Lioger, Benoit De Wazieres, Zahir Amoura, Anne-Laure Buchdaul, Sophie Georgin-Lavialle, Jérémie Dion, Serge Madaule, Loïc Raffray, Pascal Cathebras, Jean Charles Piette, Christian Rose, Jean Marc Ziza, Olivier Lortholary, Francois Montestruc, Mohammed Omouri, Guillaume Denis, Julien Rossignol, Stanislas Nimubona, Lionel Adès, Claude Gardin, Pierre Fenaux & Olivier Fain. (2016) Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study. Rheumatology 55:2, pages 291-300.
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Ofir Wolach & Richard Stone. (2016) Autoimmunity and Inflammation in Myelodysplastic Syndromes. Acta Haematologica 136:2, pages 108-117.
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Jung-Hoon BaekHyun-Jung ChunYoun-Hee ParkJeong-Hyeon ChoSang-Kyun BaeYou Jung Ha. (2013) A Case of Behcet's Disease Associated with Schizophrenia and Myelodysplastic Syndrome with Trisomy 8 and 9. Journal of Rheumatic Diseases 20:6, pages 369.
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Jian Huang, Ting Ding, Min Yang, Hui Liu, Xin Sun & Jie Jin. (2011) Antitumor activity and drug interactions of proteasome inhibitor Bortezomib in human high-risk myelodysplastic syndrome cells. International Journal of Hematology 93:4, pages 482-493.
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Aric Parnes, Sarah Nikiforow, Nancy Berliner & Gary J. Vanasse. (2010) correspondence: Single nucleotide polymorphisms in the human TNF gene are associated with anaemia and neutropenia in a cohort of patients with de novo myelodysplastic syndrome. British Journal of Haematology 150:6, pages 700-701.
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Lisa Pleyer, Daniel Neureiter, Victoria Faber & Richard Greil. 2010. Chronic Myeloid Neoplasias and Clonal Overlap Syndromes. Chronic Myeloid Neoplasias and Clonal Overlap Syndromes 153 222 .
Frances Balkwill. (2009) Tumour necrosis factor and cancer. Nature Reviews Cancer 9:5, pages 361-371.
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E.R. Brown, K.A. Charles, S.A. Hoare, R.L. Rye, D.I. Jodrell, R.E. Aird, R. Vora, U. Prabhakar, M. Nakada, R.E. Corringham, M. DeWitte, C. Sturgeon, D. Propper, F.R. Balkwill & J.F. Smyth. (2008) A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer. Annals of Oncology 19:7, pages 1340-1346.
Crossref
Rosangela Invernizzi & Erica Travaglino. (2008) Increased Apoptosis as a Mechanism of Ineffective Erythropoiesis in Myelodysplastic Syndromes. Clinical Leukemia 2:2, pages 113-120.
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Frances Balkwill. (2006) TNF-α in promotion and progression of cancer. Cancer and Metastasis Reviews 25:3, pages 409-416.
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Li Yan, G. Mark Anderson, Mark DeWitte & Marian T. Nakada. (2006) Therapeutic potential of cytokine and chemokine antagonists in cancer therapy. European Journal of Cancer 42:6, pages 793-802.
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Magda Elkabani & Alan F List. (2006) Management of Transfusion-Dependent Myelodysplastic Syndromes. American Journal of Cancer 5:2, pages 71-80.
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. (2005) Current Awareness in Hematological Oncology. Hematological Oncology 23:2, pages 82-89.
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