Advanced search
Publication Cover
Leukemia & Lymphoma Volume 45, 2004 - Issue 8
Submit an article Journal homepage
268
Views
47
CrossRef citations to date
0
Altmetric
Original Article

The Effect of Anti-CD44 Monoclonal Antibodies on Differentiation and Proliferation of Human Acute Myeloid Leukemia Cells

Zeineb Gadhoum Inserm EMI 00-03, LBCH, Institut Universitaire d'Hématologie, Centre Hayem, Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010, Paris, FranceCorrespondence[email protected]
,
Jacques Delaunay Inserm U268, Laboratoire de différenciation hématopoiétique normale et leucémique, Hôpital Paul-Brousse, 14, avenue P.V. Couturier, 94807, Villejuif Cedex, France
,
Eliane Maquarre Inserm EMI 00-03, LBCH, Institut Universitaire d'Hématologie, Centre Hayem, Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010, Paris, France
,
Laetitia Durand Inserm U268, Laboratoire de différenciation hématopoiétique normale et leucémique, Hôpital Paul-Brousse, 14, avenue P.V. Couturier, 94807, Villejuif Cedex, France
,
Valérie Lancereaux Inserm EMI 00-03, LBCH, Institut Universitaire d'Hématologie, Centre Hayem, Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010, Paris, France
,
Junyuang Qi Inserm U268, Laboratoire de différenciation hématopoiétique normale et leucémique, Hôpital Paul-Brousse, 14, avenue P.V. Couturier, 94807, Villejuif Cedex, France
,
Jacqueline Robert-Lezenes Inserm EMI 00-03, LBCH, Institut Universitaire d'Hématologie, Centre Hayem, Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010, Paris, France
,
Christine Chomienne Inserm U268, Laboratoire de différenciation hématopoiétique normale et leucémique, Hôpital Paul-Brousse, 14, avenue P.V. Couturier, 94807, Villejuif Cedex, France
&
Florence Smadja-Joffe Inserm EMI 00-03, LBCH, Institut Universitaire d'Hématologie, Centre Hayem, Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010, Paris, France
 show all
Pages 1501-1510 | Received 04 Feb 2004, Published online: 26 Aug 2009

Citations (47)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

George Mattheolabakis, Lara Milane, Amit Singh & Mansoor M. Amiji. (2015) Hyaluronic acid targeting of CD44 for cancer therapy: from receptor biology to nanomedicine. Journal of Drug Targeting 23:7-8, pages 605-618.
Read now
Giovanni D'Arena, Gioacchino Calapai & Silvia Deaglio. (2014) Anti-CD44 mAb for the treatment of B-cell chronic lymphocytic leukemia and other hematological malignancies: evaluation of WO2013063498. Expert Opinion on Therapeutic Patents 24:7, pages 821-828.
Read now
Danielle J Vugts, Derrek A Heuveling, Marijke Stigter-van Walsum, Stefan Weigand, Mats Bergstrom, Guus AMS van Dongen & Tapan K Nayak. (2014) Preclinical evaluation of 89Zr-labeled anti-CD44 monoclonal antibody RG7356 in mice and cynomolgus monkeys. mAbs 6:2, pages 567-575.
Read now
Sylvia Snauwaert, Bart Vandekerckhove & Tessa Kerre. (2013) Can immunotherapy specifically target acute myeloid leukemic stem cells?. OncoImmunology 2:2.
Read now
Hao Qian, Lijuan Xia, Peixue Ling, Samuel Waxman & Yongkui Jing. (2012) CD44 ligation with A3D8 antibody induces apoptosis in acute myeloid leukemia cells through binding to CD44s and clustering lipid rafts. Cancer Biology & Therapy 13:13, pages 1276-1283.
Read now
Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio & Bruno Giardina. (2011) Cancer stem cells: the development of new cancer therapeutics. Expert Opinion on Biological Therapy 11:7, pages 875-892.
Read now
Stefan Florian, Karoline Sonneck, Alexander W. Hauswirth, Maria-Theresa Krauth, Gerit-Holger Schernthaner, Wolfgang R. Sperr & Peter Valent. (2006) Detection of molecular targets on the surface of CD34+/CD38− stem cells in various myeloid malignancies. Leukemia & Lymphoma 47:2, pages 207-222.
Read now

Articles from other publishers (40)

Ahmed A. Abd-Rabou, Ahmed M. Abdelaziz, Olfat G. Shaker & Ghada Ayeldeen. (2023) Hyaluronated nanoparticles deliver raloxifene to CD44-expressed colon cancer cells and regulate lncRNAs/miRNAs epigenetic cascade. Cancer Nanotechnology 14:1.
Crossref
Xingmei Mu, Chumao Chen, Loujie Dong, Zhaowei Kang, Zhixian Sun, Xijie Chen, Junke Zheng & Yaping Zhang. (2023) Immunotherapy in leukaemia. Acta Biochimica et Biophysica Sinica 55:6, pages 974-987.
Crossref
Theodoros Karalis & Spyros S. Skandalis. (2022) Hyaluronan network: a driving force in cancer progression. American Journal of Physiology-Cell Physiology 323:1, pages C145-C158.
Crossref
Sofiane Fodil, Marine Arnaud, Camille Vaganay, Alexandre Puissant, Etienne Lengline, Nuala Mooney, Raphael Itzykson & Lara Zafrani. (2022) Endothelial cells: major players in acute myeloid leukaemia. Blood Reviews 54, pages 100932.
Crossref
Theodoros T. Karalis & Spyros S. Skandalis. 2022. The Extracellular Matrix and the Tumor Microenvironment. The Extracellular Matrix and the Tumor Microenvironment 457 494 .
Farzaneh Ghaderi, Narges Jokar, Ali Gholamrezanezhad, Majid Assadi & Hojjat Ahmadzadehfar. (2021) Toward radiotheranostics in cancer stem cells: a promising initial step for tumour eradication. Clinical and Translational Imaging 9:6, pages 561-578.
Crossref
Jin Cao, Shubhmita Bhatnagar, Jiawei Wang, Xueyong Qi, Swayam Prabha & Jayanth Panyam. (2020) Cancer stem cells and strategies for targeted drug delivery. Drug Delivery and Translational Research 11:5, pages 1779-1805.
Crossref
Zohreh Yaghobi, Aliakbar Movassaghpour, Mehdi Talebi, Mahdi Abdoli Shadbad, Khalil Hajiasgharzadeh, Shiva Pourvahdani & Behzad Baradaran. (2021) The role of CD44 in cancer chemoresistance: A concise review. European Journal of Pharmacology 903, pages 174147.
Crossref
Hendrian D Soebagjo, Nurwasis Nurwasis, Ugresone Y Bintoro & Sutiman B Soemitro. (2019) Evaluation of KI-67, Apoptosis, and Hyaluronic Acid in Grading Retinoblastoma. Folia Medica Indonesiana 55:3, pages 206.
Crossref
Fahad M. Almutairi, Ahmed A. Abd-Rabou & Mervat S. Mohamed. (2019) Raloxifene-encapsulated hyaluronic acid-decorated chitosan nanoparticles selectively induce apoptosis in lung cancer cells. Bioorganic & Medicinal Chemistry 27:8, pages 1629-1638.
Crossref
Yuxin Liu, Jan Philipp Bewersdorf, Maximilian Stahl & Amer M. Zeidan. (2019) Immunotherapy in acute myeloid leukemia and myelodysplastic syndromes: The dawn of a new era?. Blood Reviews 34, pages 67-83.
Crossref
Amir Amanzadeh, Vahid Molla-kazemiha, Saeed Samani, Mahdi Habibi-Anbouhi, Kayhan Azadmanesh, Mohsen Abolhassani & Mohammad Ali Shokrgozar. (2018) New synergistic combinations of differentiation-inducing agents in the treatment of acute promyelocytic leukemia cells. Leukemia Research 68, pages 98-104.
Crossref
Amir Amanzadeh, Fatemeh Heidarnejad, Meghdad Abdollahpour-Alitappeh, Vahid Molla-Kazemiha, Shamsi Yari, Alireza Hadizadeh-Tasbiti, Mahdi Habibi-Anbouhi, Mohsen Abolhassani & Mohammad Ali Shokrgozar. (2018) Development of high-affinity monoclonal antibody using CD44 overexpressed cells as a candidate for targeted immunotherapy and diagnosis of acute myeloid leukemia. Human Antibodies 26:1, pages 7-15.
Crossref
Smarakan Sneha, Rohit Pravin Nagare, Syama Krishna Priya, Chirukandath Sidhanth, Klaus Pors & Trivadi Sundaram Ganesan. (2017) Therapeutic antibodies against cancer stem cells: a promising approach. Cancer Immunology, Immunotherapy 66:11, pages 1383-1398.
Crossref
Antonieta Chavez-Gonzalez, Babak Bakhshinejad, Katayoon Pakravan, Monica L. Guzman & Sadegh Babashah. (2016) Novel strategies for targeting leukemia stem cells: sounding the death knell for blood cancer. Cellular Oncology 40:1, pages 1-20.
Crossref
Amritha Suresh, Rutika R. Naik & Sharmila A. Bapat. 2017. Contemporary Oral Oncology. Contemporary Oral Oncology 487 529 .
Maximilian Stahl, Tae Kon Kim & Amer M Zeidan. (2016) Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities. World Journal of Stem Cells 8:10, pages 316.
Crossref
A.T. Baines, P.M. Martin & C.J. Rorie. 2016. Molecular and Cellular Changes in the Cancer Cell. Molecular and Cellular Changes in the Cancer Cell 277 320 .
Phuc Van PhamPhuc Van Pham. 2015. Breast Cancer Stem Cells & Therapy Resistance. Breast Cancer Stem Cells & Therapy Resistance 75 96 .
Cord Naujokat. (2014) Monoclonal antibodies against human cancer stem cells. Immunotherapy 6:3, pages 290-308.
Crossref
Jianbiao Zhou. (2014) Identification and targeting leukemia stem cells: The path to the cure for acute myeloid leukemia. World Journal of Stem Cells 6:4, pages 473.
Crossref
Dayle A. Daines, Jingping Sun, Olga N. Uchakina & Robert J. McKallip. (2013) Development of a novel treatment for leukemia directed at tumor-associated mRNA splicing. Leukemia Research 37:9, pages 1125-1131.
Crossref
Christoph Lutz, Van T. Hoang, Eike Buss & Anthony D. Ho. (2013) Identifying leukemia stem cells – Is it feasible and does it matter?. Cancer Letters 338:1, pages 10-14.
Crossref
Van Thanh Hoang, Abraham Zepeda-Moreno & Anthony D. Ho. (2012) Identification of leukemia stem cells in acute myeloid leukemia and their clinical relevance. Biotechnology Journal 7:6, pages 779-788.
Crossref
Chao Gu, YongRui Du, Yan Gao, Zhi Yao, Xin Gu, QiuYue Zhang, JingJing Xu & WeiMin Deng. (2012) Anti-CD44 mAb remodels biological behaviors of spheroid cells with stemness from human ovarian cancer cell line SKOV-3. Chinese Science Bulletin 57:11, pages 1288-1297.
Crossref
Arnaud Sansonetti, Sébastien Bourcier, Laetitia Durand, Christine Chomienne, Florence Smadja-Joffe & Jacqueline Robert-Lézénès. (2012) CD44 activation enhances acute monoblastic leukemia cell survival via Mcl-1 upregulation. Leukemia Research 36:3, pages 358-362.
Crossref
Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio, Salvatore Scarà & Bruno Giardina. 2012. Advances in Cancer Stem Cell Biology. Advances in Cancer Stem Cell Biology 239 266 .
Robert Sackstein. (2011) The biology of CD44 and HCELL in hematopoiesis: the ‘step 2-bypass pathway’ and other emerging perspectives. Current Opinion in Hematology 18:4, pages 239-248.
Crossref
J. Loeffler-Ragg, U. Germing, W.R. Sperr, H. Herrmann, H. Zwierzina, P. Valent, H. Ulmer & R. Stauder. (2011) Serum CD44 levels predict survival in patients with low-risk myelodysplastic syndromes. Critical Reviews in Oncology/Hematology 78:2, pages 150-161.
Crossref
L.‐S. Zhang, H.‐W. Ma, H. J. Greyner, W. Zuo & M. E. Mummert. (2010) Inhibition of cell proliferation by CD44: Akt is inactivated and EGR‐1 is down‐regulated. Cell Proliferation 43:4, pages 385-395.
Crossref
Mohini Rajasagi, Anja Von Au, Rahul Singh, Natalie Hartmann, Margot Zöller & Rachid Marhaba. (2009) Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization. Journal of Cellular and Molecular Medicine 14:6b, pages 1453-1467.
Crossref
E Marangoni, N Lecomte, L Durand, G de Pinieux, D Decaudin, C Chomienne, F Smadja-Joffe & M-F Poupon. (2009) CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts. British Journal of Cancer 100:6, pages 918-922.
Crossref
Shona T. DoughertyGraeme J. Dougherty. (2009) A Cancer Gene Therapy Approach that Targets Tumor-associated Hyaluronan. Cancer Growth and Metastasis 2, pages CGM.S3716.
Crossref
Samah Zeineb Gadhoum & Robert Sackstein. (2008) CD15 expression in human myeloid cell differentiation is regulated by sialidase activity. Nature Chemical Biology 4:12, pages 751-757.
Crossref
Zhigang Xie, Pei Feng Choong, Lai Fong Poon, Jianbiao Zhou, Jiaying Khng, Viraj Janakakumara Jasinghe, Senthilnathan Palaniyandi & Chien-Shing Chen. (2008) Inhibition of CD44 expression in hepatocellular carcinoma cells enhances apoptosis, chemosensitivity, and reduces tumorigenesis and invasion. Cancer Chemotherapy and Pharmacology 62:6, pages 949-957.
Crossref
Jane L. Liesveld, Jeremy Bechelli, Karen Rosell, Chaohui Lu, Gary Bridger, Gordon PhillipsIIII & Camille N. Abboud. (2007) Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells. Leukemia Research 31:11, pages 1553-1563.
Crossref
Gang‐Ming Zou. (2007) Cancer stem cells in leukemia, recent advances. Journal of Cellular Physiology 213:2, pages 440-444.
Crossref
C Artus, E Maquarre, R S Moubarak, C Delettre, C Jasmin, S A Susin & J Robert-Lézénès. (2006) CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells. Oncogene 25:42, pages 5741-5751.
Crossref
Ronald W. Stam, Monique L. Boer & Rob Pieters. (2006) Towards targeted therapy for infant acute lymphoblastic leukaemia. British Journal of Haematology 132:5, pages 539-551.
Crossref
. (2005) Current Awareness in Hematological Oncology. Hematological Oncology 22:3, pages 135-142.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.