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Leukemia & Lymphoma Volume 47, 2006 - Issue 7
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Original

Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutations

Falk Ehmann Center of Experimental Medicine, Institute of Biochemistry and Molecular Biology I: Cellular Signal Transduction
,
Stefan Horn Center of Experimental Medicine, Institute of Biochemistry and Molecular Biology I: Cellular Signal Transduction
,
Lizet Garcia-Palma Center of Experimental Medicine, Institute of Biochemistry and Molecular Biology I: Cellular Signal Transduction
,
Wiebke Wegner Center of Experimental Medicine, Institute of Biochemistry and Molecular Biology I: Cellular Signal Transduction
,
Walter Fiedler Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany
,
Klaudia Giehl Department of Pharmacology and Toxicology, University of Ulm, Ulm, Germany
,
Georg W. Mayr Center of Experimental Medicine, Institute of Biochemistry and Molecular Biology I: Cellular Signal Transduction
&
Dr Manfred Jücker Center of Experimental Medicine, Institute of Biochemistry and Molecular Biology I: Cellular Signal TransductionCorrespondence[email protected]
 show all
Pages 1387-1391 | Received 22 Sep 2005, Accepted 28 Dec 2005, Published online: 01 Jul 2009

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Pearlie K Epling-Burnette & Thomas P Loughran Jr. (2010) Suppression of farnesyltransferase activity in acute myeloid leukemia and myelodysplastic syndrome: current understanding and recommended use of tipifarnib. Expert Opinion on Investigational Drugs 19:5, pages 689-698.
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Articles from other publishers (7)

Snigdha Samanta, Rumpa Mahata & Manas Kumar Santra. 2022. Metabolism and Epigenetic Regulation: Implications in Cancer. Metabolism and Epigenetic Regulation: Implications in Cancer 427 472 .
Tamás Takács, Gyöngyi Kudlik, Anita Kurilla, Bálint Szeder, László Buday & Virag Vas. (2020) The effects of mutant Ras proteins on the cell signalome. Cancer and Metastasis Reviews 39:4, pages 1051-1065.
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Kanae Sakakibara, Takayuki Tsujioka, Jun-ichiro Kida, Nami Kurozumi, Takako Nakahara, Shin-ichiro Suemori, Akira Kitanaka, Yujiro Arao & Kaoru Tohyama. (2019) Binimetinib, a novel MEK1/2 inhibitor, exerts anti-leukemic effects under inactive status of PI3Kinase/Akt pathway. International Journal of Hematology 110:2, pages 213-227.
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Nicola Vajente, Roberta Trevisan & Daniela Saggioro. (2008) HTLV-1 Tax protein cooperates with Ras in protecting cells from apoptosis. Apoptosis 14:2, pages 153-163.
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Samir K. Patra & Moshe Szyf. (2008) DNA methylation‐mediated nucleosome dynamics and oncogenic Ras signaling. The FEBS Journal 275:21, pages 5217-5235.
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Mitch RaponiJeffrey E. LancetHongtao FanLesley DosseyGrace LeeIvana GojoEric J. FeldmanJason GotlibLawrence E. MorrisPeter L. GreenbergJohn J. WrightJean-Luc HarousseauBob LöwenbergRichard M. StonePeter De Porre, Yixin WangJudith E. Karp. (2008) A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia. Blood 111:5, pages 2589-2596.
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Claude Gazin, Narendra Wajapeyee, Stephane Gobeil, Ching-Man Virbasius & Michael R. Green. (2007) An elaborate pathway required for Ras-mediated epigenetic silencing. Nature 449:7165, pages 1073-1077.
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