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Letter to the Editor

Remission of Philadelphia chromosome-positive central nervous system leukemia after dasatinib therapy

, , , , , & , MD show all
Pages 1053-1056 | Received 19 Dec 2006, Accepted 02 Feb 2007, Published online: 01 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Qiuxia Yu, Gaoxiang Wang, Jue Wang, Wei Zhang, Li Meng & Yang Cao. (2022) Primary Testicular and Cutaneous Philadelphia Chromosome Positive B-Cell Lymphoblastic Lymphoma: A Rare Case and Review. Cancer Management and Research 14, pages 1507-1514.
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Françoise Huguet. (2015) Dasatinib for acute lymphoblastic leukemia. Expert Opinion on Orphan Drugs 3:11, pages 1339-1356.
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Charles Chuah & Junia V Melo. (2009) Targeted treatment of imatinib-resistant chronic myeloid leukemia: Focus on dasatinib. OncoTargets and Therapy 2, pages 83-94.
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Thomas R Webb, Jake Slavish, Rani E George, A Thomas Look, Liquan Xue, Qin Jiang, Xiaoli Cui, Walter B Rentrop & Stephan W Morris. (2009) Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy. Expert Review of Anticancer Therapy 9:3, pages 331-356.
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Xiaoyuan Gong, Le Li, Hui Wei, Bingcheng Liu, Chunlin Zhou, Guangji Zhang, Kaiqi Liu, Dong Lin, Benfa Gong, Shuning Wei, Yan Li, Yingchang Mi, Ying Wang & Jianxiang Wang. (2021) A Higher Dose of Dasatinib May Increase the Possibility of Crossing the Blood–brain Barrier in the Treatment of Patients With Philadelphia Chromosome–positive Acute Lymphoblastic Leukemia. Clinical Therapeutics 43:7, pages 1265-1271.e1.
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Yu Wei, Mi Ryung Shin & Federico Sesti. (2018) Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer’s disease. Cell Death & Disease 9:8.
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SHIUE-WEI LAI, TZU-CHUAN HUANG, JIA-HONG CHEN, YI-YING WU & PING-YING CHANG. (2015) Dasatinib as the salvage therapy for chronic myeloid leukemia with blast crisis and central nervous system involvement: A case report. Oncology Letters 9:4, pages 1957-1961.
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Toshinori Kondo, Taizo Tasaka, Kana Matsumoto, Rui Matsumoto, Lisa Koresawa, Fuminori Sano, Hirotoshi Tokunaga, Yoshiko Matsuhashi, Hidekazu Nakanishi, Kunihiko Morita, Hideho Wada & Takashi Sugihara. (2014) Philadelphia chromosome-positive acute lymphoblastic leukemia with extramedullary and meningeal relapse after allogeneic hematopoietic stem cell transplantation that was successfully treated with dasatinib. SpringerPlus 3:1.
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Diana S. Osorio, Jonathan L. Finlay, Girish Dhall, Stewart Goldman, David Eisenstat & Robert J. Brown. (2013) Feasibility of dasatinib in children and adolescents with new or recurrent central nervous system germinoma. Pediatric Blood & Cancer 60:9, pages E100-E102.
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Mitsutaka Nishimoto, Hirohisa Nakamae, Ki-Ryang Koh, Saori Kosaka, Kana Matsumoto, Kunihiko Morita, Hideo Koh, Takahiko Nakane, Masahiko Ohsawa & Masayuki Hino. (2013) Dasatinib Maintenance Therapy after Allogeneic Hematopoietic Stem Cell Transplantation for an Isolated Central Nervous System Blast Crisis in Chronic Myelogenous Leukemia. Acta Haematologica 130:2, pages 111-114.
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Kapil Bhalla, Celalettin Ustun & Warren Fiskus. 2012. Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics. Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics 277 314 .
Sotirios G. Papageorgiou, Vasiliki Pappa, Christina Economopoulou, Panagiotis Tsirigotis, Frida Konsioti, Eleni-Dikaia Ionnidou, Spyros Chondropoulos, Diamantina Vasilatou, Efstathios Papageorgiou, Theofanis Economopoulos & John Dervenoulas. (2010) Dasatinib induces long-term remission in imatinib-resistant Philadelphia chromosome-positive acute megakaryoblastic leukemia but fails to prevent development of central nervous system progression. Leukemia Research 34:9, pages e254-e256.
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Philippe Aftimos & Fady Nasr. (2009) Isolated CNS lymphoid blast crisis in a patient with imatinib-resistant chronic myelogenous leukemia: Case report and review of the literature. Leukemia Research 33:11, pages e178-e180.
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Franz Gruber, Satu Mustjoki & Kimmo Porkka. (2009) Impact of tyrosine kinase inhibitors on patient outcomes in Philadelphia chromosome-positive acute lymphoblastic leukaemia. British Journal of Haematology 145:5, pages 581-597.
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Ferdinando Frigeri, Manuela Arcamone, Luigia Luciano, Raffaele Di Francia, Fabrizio Pane & Antonio Pinto. (2009) Systemic dasatinib fails to prevent development of central nervous system progression in a patient with BCR-ABL unmutated Philadelphia chromosome–positive leukemia. Blood 113:20, pages 5028-5029.
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Kimmo Porkka, Perttu Koskenvesa, Tuija LundánJohanna RimpiläinenSatu Mustjoki, Richard SmyklaRobert WildRoger LuoMontserrat ArnanBenoit BrethonLydia EccersleyHenrik Hjorth-HansenMartin HöglundHana KlamovaHåvar KnutsenSuhag ParikhEmmanuel RaffouxFranz GruberFinella Brito-BabapulleHervé DombretRafael F. DuarteErkki Elonen, Ron PaquetteC. Michel Zwaan & Francis Y. F. Lee. (2008) Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia. Blood 112:4, pages 1005-1012.
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Peter Valent. (2008) Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease. British Journal of Haematology 142:3, pages 361-378.
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