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Leukemia & Lymphoma Volume 49, 2008 - Issue 4
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Focused Reviews in CML

Pharmacologic markers and predictors of responses to imatinib therapy in patients with chronic myeloid leukemia

Richard E. Clark University Department of Haematology, Royal Liverpool University Hospital, Liverpool, UKCorrespondence[email protected]
,
Andrea Davies University Department of Haematology, Royal Liverpool University Hospital, Liverpool, UK
,
Munir Pirmohamed Department of Pharmacology and Therapeutics, The University of Liverpool, Liverpool, UK
&
Athina Giannoudis University Department of Haematology, Royal Liverpool University Hospital, Liverpool, UK
Pages 639-642 | Published online: 01 Jul 2009

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Marta Gromicho, Joana Dinis, Marta Magalhães, Alexandra R. Fernandes, Purificação Tavares, António Laires, José Rueff & António Sebastião Rodrigues. (2011) Development of imatinib and dasatinib resistance: dynamics of expression of drug transporters ABCB1, ABCC1, ABCG2, MVP, and SLC22A1. Leukemia & Lymphoma 52:10, pages 1980-1990.
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Shinta Oktya Wardhani, Hani Susanti, Puji Rahayu, Yuyun Yueniwati & Jonny Fajar. (2021) The Levels of FoxO3a Predict the Failure of Imatinib Mesylate Therapy among Chronic Myeloid Leukemia Patients. Open Access Macedonian Journal of Medical Sciences 9:B, pages 255-259.
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Yuko Tanihara, Satohiro Masuda & Ken-ichi Inui. (2021) Inhibitory effects of vandetanib on creatinine transport via renal organic cation transporter OCT2. European Journal of Pharmaceutical Sciences 158, pages 105666.
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Shinta Oktya Wardhani, Hani Susianti, Puji Rahayu, Yuyun Prabowowati Yueniwati & Jonny Karunia Fajar. (2022) The association between FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a among chronic granulocytic leukemia patients treated with imatinib mesylate. F1000Research 10, pages 1003.
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Wendy Yang & Michael F. Berger. 2019. Precision Cancer Medicine. Precision Cancer Medicine 5 31 .
H-B Qiu, W Zhuang, T Wu, S Xin, C-Z Lin, H-L Ruan, X Zhu, M Huang, J-L Li, X-Y Hou, Z-W Zhou & X-D Wang. (2017) Imatinib-induced ophthalmological side-effects in GIST patients are associated with the variations of EGFR, SLC22A1, SLC22A5 and ABCB1. The Pharmacogenomics Journal 18:3, pages 460-466.
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Natalia Weich, Cristian Ferri, Beatriz Moiraghi, Raquel Bengió, Isabel Giere, Carolina Pavlovsky, Irene Larripa & Ariela Fundia. (2016) TP53 codon 72 polymorphism predicts chronic myeloid leukemia susceptibility and treatment outcome. Blood Cells, Molecules, and Diseases 59, pages 129-133.
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Marta Gromicho, José Rueff & António Sebastião Rodrigues. 2016. Cancer Drug Resistance. Cancer Drug Resistance 75 85 .
Pia Raanani, Galit Granot & Isaac Ben-Bassat. (2014) Is cure of chronic myeloid leukemia in the third millennium a down to earth target (ed) or a castle in the air?. Cancer Letters 352:1, pages 21-27.
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Srijib Goswami, Li Gong, Kathleen Giacomini, Russ B. Altman & Teri E. Klein. (2014) PharmGKB summary. Pharmacogenetics and Genomics 24:6, pages 324-328.
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Jason A. Sprowl & Alex Sparreboom. (2014) Uptake Carriers and Oncology Drug Safety. Drug Metabolism and Disposition 42:4, pages 611-622.
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Rui Lin, Xiaoli Li, Jiansheng Li, Lianfeng Zhang, Feng Xu, Yanjun Chu & Jichang Li. (2012) Long-Term Cisplatin Exposure Promotes Methylation of the OCT1 Gene in Human Esophageal Cancer Cells. Digestive Diseases and Sciences 58:3, pages 694-698.
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Michael Heise, Anja Lautem, Johanna Knapstein, Jörn M Schattenberg, Maria Hoppe-Lotichius, Daniel Foltys, Nina Weiler, Anca Zimmermann, Arno Schad, Dirk Gründemann, Gerd Otto, Peter R Galle, Marcus Schuchmann & Tim Zimmermann. (2012) Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance. BMC Cancer 12:1.
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Marta Gromicho. (2012) Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib. Oncology Reports.
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Deborah L. WhitePhuong DangJane EnglerAmity FredeStephanie ZrimMichael OsbornVerity A. SaundersPaul W. ManleyTimothy P. Hughes. (2010) Functional Activity of the OCT-1 Protein Is Predictive of Long-Term Outcome in Patients With Chronic-Phase Chronic Myeloid Leukemia Treated With Imatinib. Journal of Clinical Oncology 28:16, pages 2761-2767.
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Wenyong W. ZhangJorge E. CortesHui YaoLi ZhangNeelima G. ReddyElias JabbourHagop M. KantarjianDan Jones. (2009) Predictors of Primary Imatinib Resistance in Chronic Myelogenous Leukemia Are Distinct From Those in Secondary Imatinib Resistance. Journal of Clinical Oncology 27:22, pages 3642-3649.
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. (2008) Current Awareness in Hematological Oncology. Hematological Oncology 26:4, pages 253-260.
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