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Leukemia & Lymphoma Volume 49, 2008 - Issue 8
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Original Articles: Clinical

Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia

Arati V. Rao Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USACorrespondence[email protected]
,
Islam R. Younis Department of Basic Pharmaceutical Sciences and MBR Cancer Center, West Virginia University, Morgantown, WV, USA
,
Gregory J. Sand Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
,
Ivan Spasojevic Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
,
David J. Adams Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
,
Carlos M. Decastro Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
,
John P. Gockerman Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
,
Bercedis L. Peterson Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC
,
William P. Petros Department of Basic Pharmaceutical Sciences and MBR Cancer Center, West Virginia University, Morgantown, WV, USA
,
Joseph O. Moore Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
&
David A. Rizzieri Department of Medicine, Divisions of Medical Oncology, Pharmacology, and Cellular Therapy, Duke University Medical Center, Durham, NC, USA
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Pages 1523-1529 | Received 28 Mar 2008, Accepted 17 May 2008, Published online: 01 Jul 2009

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Cody Chiuzan, Jonathan Shtaynberger, Gulam A. Manji, Jimmy K. Duong, Gary K. Schwartz, Anastasia Ivanova & Shing M. Lee. (2017) Dose-finding designs for trials of molecularly targeted agents and immunotherapies. Journal of Biopharmaceutical Statistics 27:3, pages 477-494.
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Articles from other publishers (1)

Arati V. Rao, David A. Rizzieri, Carlos M. DeCastro, Louis F. Diehl, Anand S. Lagoo, Joseph O. Moore & Jon P. Gockerman. (2012) Phase I study of dose dense induction and consolidation with gemtuzumab ozogamicin and high dose cytarabine in older adults with AML. Journal of Geriatric Oncology 3:3, pages 220-227.
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