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Original Articles: Clinical

Elevated pretreatment interleukin-10 serum level is an International Prognostic Score (IPS)-independent risk factor for early treatment failure in advanced stage Hodgkin lymphoma

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Pages 2091-2098 | Received 12 Feb 2008, Accepted 27 Aug 2008, Published online: 01 Jul 2009

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Read on this site (8)

Adam J. Olszewski. (2022) Ferritin, sex, and the wildfire of inflammation in Hodgkin lymphoma. Leukemia & Lymphoma 63:4, pages 765-767.
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Gabriela Vera-Lozada, Carolina Minnicelli, Priscilla Segges, Gustavo Stefanoff, Flavia Kristcevic, Joaquin Ezpeleta, Elizabeth Tapia, Gerald Niedobitek, Mário Henrique M. Barros & Rocio Hassan. (2018) Interleukin 10 (IL10) proximal promoter polymorphisms beyond clinical response in classical Hodgkin lymphoma: Exploring the basis for the genetic control of the tumor microenvironment. OncoImmunology 7:5.
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Ravnit Grewal, Alexandra Irimie, Nasheen Naidoo, Nooroudien Mohamed, Bobe Petrushev, Manogari Chetty, Ciprian Tomuleasa & Emmanuel-Akinola Abayomi. (2018) Hodgkin’s lymphoma and its association with EBV and HIV infection. Critical Reviews in Clinical Laboratory Sciences 55:2, pages 102-114.
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Martin S. Staege, Stefanie Kewitz, Toralf Bernig, Caspar Kühnöl & Christine Mauz-Körholz. (2015) Prognostic Biomarkers for Hodgkin Lymphoma. Pediatric Hematology and Oncology 32:7, pages 433-454.
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Olav E. Yri, Per O. Ekstrøm, Vera Hilden, Gustav Gaudernack, Knut Liestøl, Erlend B. Smeland & Harald Holte. (2012) Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma. Leukemia & Lymphoma 53:10, pages 1934-1944.
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Boris Böll, Peter Borchmann & Volker Diehl. (2010) Emerging drugs for Hodgkin's lymphoma. Expert Opinion on Emerging Drugs 15:4, pages 585-595.
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Bharti Rathore & Marshall E Kadin. (2010) Hodgkin's lymphoma therapy: past, present, and future. Expert Opinion on Pharmacotherapy 11:17, pages 2891-2906.
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Otavio C. G. Baiocchi. (2008) Hodgkin lymphoma and interleukin-10: shall we go down from the tip of the iceberg?. Leukemia & Lymphoma 49:11, pages 2031-2032.
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Articles from other publishers (19)

Poonam Nagpal, Dante B. Descalzi‐Montoya & Niraj Lodhi. (2020) The circuitry of the tumor microenvironment in adult and pediatric Hodgkin lymphoma: cellular composition, cytokine profile, EBV , and exosomes . Cancer Reports 4:2.
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Jennifer E. Agrusa, Brooks P. Scull, Harshal A. Abhyankar, Howard Lin, Nmazuo W. Ozuah, Rikhia Chakraborty, Olive S. Eckstein, Nitya Gulati, Elmoataz Abdel Fattah, Nader K. El-Mallawany, Rayne H. Rouce, ZoAnn E. Dreyer, Julienne Brackett, Judith F. Margolin, Joseph Lubega, Terzah M. Horton, Catherine M. Bollard, M. Monica Gramatges, Kala Y. Kamdar, Kenneth L. McClain, Tsz-Kwong Man & Carl E. Allen. (2020) Defining the Inflammatory Plasma Proteome in Pediatric Hodgkin Lymphoma. Cancers 12:12, pages 3603.
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Young-Woong Won, Hyewon Lee, Hyeon-Seok Eom, Jin Seok Kim, Cheolwon Suh, Dok Hyun Yoon, Jung Yong Hong, Hye Jin Kang, Jae Hoon Lee, Won Seog Kim, Seok Jin Kim, Won-Sik Lee, Myung Hee Chang, Young Rok Do, Jun Ho Yi, Inho Kim, Jong-Ho Won, Kyoungha Kim, Sung Yong Oh & Jae-Cheol Jo. (2020) A phase II study of etoposide, methylprednisolone, high-dose cytarabine, and oxaliplatin (ESHAOx) for patients with refractory or relapsed Hodgkin’s lymphoma. Annals of Hematology 99:2, pages 255-264.
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Marcus P. Watkins, Michelle A. Fanale & Nancy L. Bartlett. (2018) SOHO State of the Art Updates and Next Questions: Hodgkin Lymphoma. Clinical Lymphoma Myeloma and Leukemia 18:2, pages 81-90.
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Catherine S. Diefenbach, Joseph M. Connors, Jonathan W. Friedberg, John P. Leonard, Brad S. Kahl, Richard F. Little, Lawrence Baizer, Andrew M. Evens, Richard T. Hoppe, Kara M. Kelly, Daniel O. Persky, Anas Younes, Lale Kostakaglu & Nancy L. Bartlett. (2016) Hodgkin Lymphoma: Current Status and Clinical Trial Recommendations. Journal of the National Cancer Institute 109:4, pages djw249.
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Antonino Carbone & Anas YounesCatherine Diefenbach & Christian Steidl. 2015. Hodgkin And Non-Hodgkin Lymphomas Seen Through Their Microenvironment: Impact on Diagnosis, Prognosis and Innovative Therapy (Volume 2). Hodgkin And Non-Hodgkin Lymphomas Seen Through Their Microenvironment: Impact on Diagnosis, Prognosis and Innovative Therapy (Volume 2) 20 34 .
Tamar Tadmor, Alessia Bari, Luigi Marcheselli, Stefano Sacchi, Ariel Aviv, Luca Baldini, Paolo G. Gobbi, Samantha Pozzi, Paola Ferri, Maria Christina Cox, Nicola Cascavilla, Emilio Iannitto, Massimo Federico & Aaron Polliack. (2015) Absolute Monocyte Count and Lymphocyte-Monocyte Ratio Predict Outcome in Nodular Sclerosis Hodgkin Lymphoma: Evaluation Based on Data From 1450 Patients. Mayo Clinic Proceedings 90:6, pages 756-764.
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Priscilla Brito da Silva, Guilherme Fleury Perini, Luciana de Andrade Pereira, Elyse Moritz Sacconato, Adriana Marques Damasco Penna, Joao Garibaldi, Egyla Cavalcante & Otavio C.G. Baiocchi. (2015) Imbalance of Pro- and Anti-Inflammatory Cytokines in Patients With cHL Persists Despite Treatment Compared With Control Subjects. Clinical Lymphoma Myeloma and Leukemia 15, pages S151-S157.
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Joseph M. Connors. (2015) Risk assessment in the management of newly diagnosed classical Hodgkin lymphoma. Blood 125:11, pages 1693-1702.
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Silke Reinartz, Tim Schumann, Florian Finkernagel, Annika Wortmann, Julia M. Jansen, Wolfgang Meissner, Michael Krause, Anne‐Marie Schwörer, Uwe Wagner, Sabine Müller‐Brüsselbach & Rolf Müller. (2013) Mixed‐polarization phenotype of ascites‐associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse. International Journal of Cancer 134:1, pages 32-42.
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Preethi Reddy Marri, Lucy S. Hodge, Matthew J. Maurer, Steven C. Ziesmer, Susan L. Slager, Thomas M. Habermann, Brian K. Link, James R. Cerhan, Anne J. Novak & Stephen M. Ansell. (2013) Prognostic Significance of Pretreatment Serum Cytokines in Classical Hodgkin Lymphoma. Clinical Cancer Research 19:24, pages 6812-6819.
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Ghada Kchour, SA Rahim Rezaee, Reza Farid, Akram Ghantous, Houshang Rafatpanah, Mahdi Tarhini, Mohamad-Mehdi Kooshyar, Hiba El Hajj, Fadwa Berry, Mohamad Mortada, Roudaina Nasser, Abbas Shirdel, Zeina Dassouki, Mohamad Ezzedine, Hossein Rahimi, Ardeshir Ghavamzadeh, Hugues de Thé, Olivier Hermine, Mahmoud Mahmoudi & Ali Bazarbachi. (2013) The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma. Retrovirology 10:1.
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GUANG-HONG GUO, JIN DONG, XIN-HONG YUAN, ZHEN-NAN DONG & YA-PING TIAN. (2013) Clinical evaluation of the levels of 12 cytokines in serum/plasma under various storage conditions using evidence biochip arrays. Molecular Medicine Reports 7:3, pages 775-780.
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Nils SchoofJeremy FranklinRobert FürstThomas ZanderFrederike von BoninFrederic PeyradeLorenz TrümperVolker DiehlAndreas EngertDieter KubeDaniel Re. (2013) Interleukin-10 Gene Polymorphisms are Associated With Freedom From Treatment Failure for Patients With Hodgkin Lymphoma. The Oncologist 18:1, pages 80-89.
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Maria Kowalska, Joanna Tajer, Magdalena Chechlinska, Malgorzata Fuksiewicz, Beata Kotowicz, Ma?gorzata Syczewska, Jan Walewski & Janina Kaminska. (2012) Discriminant analysis involving serum cytokine levels and prediction of the response to therapy of patients with Hodgkin lymphoma. Tumor Biology 33:5, pages 1733-1738.
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Ljubomir R. Jakovic, Biljana S. Mihaljevic, Maja D. Perunicic Jovanovic, Andrija D. Bogdanovic, Bosko M. Andjelic & Vladimir Z. Bumbasirevic. (2012) Prognostic Significance of Bcl-2, Tumor-Associated Macrophages, and Total Neoplastic and Inflammatory Lymph Node Involvement in Advanced Stage Classical Hodgkin’s Lymphoma. Oncology Research and Treatment 35:12, pages 733-739.
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Rafael D Gaiolla, Maria A. C Domingues, Lígia Niéro-Melo & Deilson Elgui de Oliveira. (2011) Serum Levels of Interleukins 6, 10, and 13 Before and After Treatment of Classic Hodgkin Lymphoma. Archives of Pathology & Laboratory Medicine 135:4, pages 483-489.
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Donatella Aldinucci, Annunziata Gloghini, Antonio Pinto, Rosaria De Filippi & Antonino Carbone. (2010) The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape. The Journal of Pathology 221:3, pages 248-263.
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Lara Cattaruzza, Annunziata Gloghini, Karin Olivo, Raffaele Di Francia, Debora Lorenzon, Rosaria De Filippi, Antonino Carbone, Alfonso Colombatti, Antonio Pinto & Donatella Aldinucci. (2009) Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma. International Journal of Cancer 125:5, pages 1092-1101.
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