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Letters to the Editor

The hedgehog inhibitor cyclopamine induces apoptosis in leukemic cells in vitro

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Pages 2383-2386 | Received 07 Apr 2008, Accepted 26 Sep 2008, Published online: 01 Jul 2009

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Lingyun Geng & Xin Wang. (2015) New insight into hedgehog signaling in hematological malignancies. Leukemia & Lymphoma 56:4, pages 858-865.
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Xian Zeng, Hui Zhao, Yubin Li, Jiajun Fan, Yun Sun, Shaofei Wang, Ziyu Wang, Ping Song & Dianwen Ju. (2015) Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia. Autophagy 11:2, pages 355-372.
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Muzafar A Macha, Surinder K Batra & Apar Kishor Ganti. (2013) Profile of vismodegib and its potential in the treatment of advanced basal cell carcinoma. Cancer Management and Research 5, pages 197-203.
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Tara L Lin & William Matsui. (2012) Hedgehog pathway as a drug target: Smoothened inhibitors in development. OncoTargets and Therapy 5, pages 47-58.
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Articles from other publishers (7)

Xiaoming Liu, Jichun Liu, Xuekang Zhang, Yuben Tong & Xin Gan. (2019) MiR-520b promotes the progression of non-small cell lung cancer through activating Hedgehog pathway. Journal of Cellular and Molecular Medicine 23:1, pages 205-215.
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Lingyun Geng, Kang Lu, Peipei Li, Xinyu Li, Xiangxiang Zhou, Ying Li & Xin Wang. (2016) GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3. Oncotarget 8:30, pages 48701-48710.
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Alessandra Chiarenza, Fabrizio Manetti, Elena Petricci, Martial Ruat, Antonella Naldini, Maurizio Taddei & Fabio Carraro. (2016) Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells. PLOS ONE 11:3, pages e0149919.
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Philipp Heretsch & Athanassios Giannis. 2015. 201 232 .
Philipp Heretsch & Athanassios Giannis. 2014. Natural Products in Medicinal Chemistry. Natural Products in Medicinal Chemistry 545 564 .
Tara L. Lin, Qiuju H. Wang, Patrick Brown, Craig Peacock, Akil A. Merchant, Sarah Brennan, Evan Jones, Karen McGovern, D. Neil Watkins, Kathleen M. Sakamoto & William Matsui. (2010) Self-Renewal of Acute Lymphocytic Leukemia Cells Is Limited by the Hedgehog Pathway Inhibitors Cyclopamine and IPI-926. PLoS ONE 5:12, pages e15262.
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Sabino Ciavarella, Annalisa Milano, Franco Dammacco & Franco Silvestris. (2010) Targeted Therapies in Cancer. BioDrugs 24:2, pages 77-88.
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