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Leukemia & Lymphoma Volume 50, 2009 - Issue 5
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Original Article: Research

Interleukin-6-independent expression of glucocorticoid receptor is upregulated by triptolide in multiple myeloma

Min Yang Department of Hematology, The First Affiliated Hospital, Institute of Hematology, Zhejiang University, School of Medicine, Zhejiang Province, People's Republic of China; Key Laboratory of Hematology, Diagnose and Treatment, Zhejiang Province, People's Republic of China
,
Jia-Kun Shen Department of Hematology, The First Affiliated Hospital, Institute of Hematology, Zhejiang University, School of Medicine, Zhejiang Province, People's Republic of China; Key Laboratory of Hematology, Diagnose and Treatment, Zhejiang Province, People's Republic of China
,
Jian Huang Department of Hematology, The First Affiliated Hospital, Institute of Hematology, Zhejiang University, School of Medicine, Zhejiang Province, People's Republic of China; Key Laboratory of Hematology, Diagnose and Treatment, Zhejiang Province, People's Republic of China
,
Hua-Ping Du Department of Hematology, The First Affiliated Hospital, Institute of Hematology, Zhejiang University, School of Medicine, Zhejiang Province, People's Republic of China; Key Laboratory of Hematology, Diagnose and Treatment, Zhejiang Province, People's Republic of China
,
Qiu-Ling Ma Department of Hematology, The First Affiliated Hospital, Institute of Hematology, Zhejiang University, School of Medicine, Zhejiang Province, People's Republic of China; Key Laboratory of Hematology, Diagnose and Treatment, Zhejiang Province, People's Republic of China
&
Jie Jin Department of Hematology, The First Affiliated Hospital, Institute of Hematology, Zhejiang University, School of Medicine, Zhejiang Province, People's Republic of China; Key Laboratory of Hematology, Diagnose and Treatment, Zhejiang Province, People's Republic of China; Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, Hangzhou, ChinaCorrespondence[email protected]
, MD, PhD
Pages 802-808 | Received 28 Nov 2008, Accepted 04 Feb 2009, Published online: 21 Jul 2009

Citations (6)

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Xin Huang, Min Yang & Jie Jin. (2012) Triptolide enhances the sensitivity of multiple myeloma cells to dexamethasone via microRNAs. Leukemia & Lymphoma 53:6, pages 1188-1195.
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Articles from other publishers (5)

TOMONORI NAKAZATO, MORIHIKO SAGAWA & MASAHIRO KIZAKI. (2014) Triptolide induces apoptotic cell death of multiple myeloma cells via transcriptional repression of Mcl-1. International Journal of Oncology 44:4, pages 1131-1138.
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Sulagna Banerjee, Venugopal Thayanithy, Veena Sangwan, Tiffany N. Mackenzie, Ashok K. Saluja & Subbaya Subramanian. (2013) Minnelide reduces tumor burden in preclinical models of osteosarcoma. Cancer Letters 335:2, pages 412-420.
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Fei Zhao, Yan Chen, Linglan Zeng, Rui Li, Rong Zeng, Lu Wen, Yuan Liu & Chun Zhang. (2010) Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells. European Journal of Pharmacology 646:1-3, pages 1-11.
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Fei Zhao, Ling-lan Zeng, Yan Chen, Rui Li, Yuan Liu, Lu Wen, Yi-quan Cheng & Chun Zhang. (2010) Effects of triptolide on histone acetylation and HDAC8 expression in multiple myeloma in vitro. Chinese Journal of Cancer Research 22:2, pages 148-155.
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Fei Zhao, Yan Chen, Rui Li, Yuan Liu, Lu Wen & Chun Zhang. (2010) Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro. Toxicology 267:1-3, pages 70-79.
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