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Original Article: Clinical

A novel regimen combining high dose cytarabine and bortezomib has activity in multiply relapsed and refractory mantle cell lymphoma – long-term results of a multicenter observation study

, MD, , , , , , , & show all
Pages 716-722 | Received 21 Nov 2008, Accepted 28 Feb 2009, Published online: 21 Jul 2009

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Tadeusz Robak, Piotr Smolewski, Pawel Robak & Martin Dreyling. (2019) Mantle cell lymphoma: therapeutic options in transplant-ineligible patients. Leukemia & Lymphoma 60:11, pages 2622-2634.
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Richard Arkwright, Tri Minh Pham, Jeffrey A. Zonder & Q. Ping Dou. (2017) The preclinical discovery and development of bortezomib for the treatment of mantle cell lymphoma. Expert Opinion on Drug Discovery 12:2, pages 225-235.
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Jeanette K Doorduijn & Hanneke C Kluin-Nelemans. (2013) Management of mantle cell lymphoma in the elderly patient. Clinical Interventions in Aging 8, pages 1229-1236.
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C. Tom Kouroukis, Louis A. V. Fernandez, Michael Crump, Neil Sun Chua, Rena Buckstein, Robert Turner, Sarit Assouline, Richard J. Klasa, Wendy Walsh, Jean Powers & Elizabeth Eisenhauer. (2011) A phase II study of bortezomib and gemcitabine in relapsed mantle cell lymphoma from the National Cancer Institute of Canada Clinical Trials Group (IND 172). Leukemia & Lymphoma 52:3, pages 394-399.
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Bhupender S Chhikara & Keykavous Parang. (2010) Development of cytarabine prodrugs and delivery systems for leukemia treatment. Expert Opinion on Drug Delivery 7:12, pages 1399-1414.
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Elisabeth Silkenstedt, Kim Linton & Martin Dreyling. (2021) Mantle cell lymphoma – advances in molecular biology, prognostication and treatment approaches. British Journal of Haematology 195:2, pages 162-173.
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Pamela McKay, Mike Leach, Bob Jackson, Stephen Robinson & Simon Rule. (2018) Guideline for the management of mantle cell lymphoma. British Journal of Haematology 182:1, pages 46-62.
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Christian W. Eskelund, Christina Dahl, Jakob W. Hansen, Maj Westman, Arne Kolstad, Lone B. Pedersen, Carmen P. Montano-Almendras, Simon Husby, Catja Freiburghaus, Sara Ek, Anja Pedersen, Carsten Niemann, Riikka Räty, Peter Brown, Christian H. Geisler, Mette K. Andersen, Per Guldberg, Mats Jerkeman & Kirsten Grønbæk. (2017) TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy . Blood 130:17, pages 1903-1910.
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Bryan Hambley, Paolo F. Caimi & Basem M. William. (2016) Bortezomib for the treatment of mantle cell lymphoma: an update. Therapeutic Advances in Hematology 7:4, pages 196-208.
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Shundong Cang, Nikhil Mukhi, Kemeng Wang & Delong Liu. (2012) Novel CD20 monoclonal antibodies for lymphoma therapy. Journal of Hematology & Oncology 5:1.
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M. Witzens-Harig, G. Hess, J. Atta, M. Zaiss, G. Lenz, C. Scholz, R. Repp, M. Reiser, C. Pott, H. Pelz, P. La Rosée, H. Kirchner, P. Kiewe, U. Keller, C. Buske, A. Viardot & M. Dreyling. (2012) Current treatment of mantle cell lymphoma: results of a national survey and consensus meeting. Annals of Hematology 91:11, pages 1765-1772.
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H.C. Kluin-Nelemans, E. Hoster, O. Hermine, J. Walewski, M. Trneny, C.H. Geisler, S. Stilgenbauer, C. Thieblemont, U. Vehling-Kaiser, J.K. Doorduijn, B. Coiffier, R. Forstpointner, H. Tilly, L. Kanz, P. Feugier, M. Szymczyk, M. Hallek, S. Kremers, G. Lepeu, L. Sanhes, J.M. Zijlstra, R. Bouabdallah, P.J. Lugtenburg, M. Macro, M. Pfreundschuh, V. Proch?zka, F. Di Raimondo, V. Ribrag, M. Uppenkamp, M. Andr?W. Klapper, W. Hiddemann, M. Unterhalt & M.H. Dreyling. (2012) Treatment of Older Patients with Mantle-Cell Lymphoma. New England Journal of Medicine 367:6, pages 520-531.
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Beata Holkova & Steven Grant. (2012) Proteasome inhibitors in mantle cell lymphoma. Best Practice & Research Clinical Haematology 25:2, pages 133-141.
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Grit Hutter, Malte Rieken, Alessandro Pastore, Oliver Weigert, Yvonne Zimmermann, Marc Weinkauf, Wolfgang Hiddemann & Martin Dreyling. (2012) The proteasome inhibitor bortezomib targets cell cycle and apoptosis and acts synergistically in a sequence-dependent way with chemotherapeutic agents in mantle cell lymphoma. Annals of Hematology 91:6, pages 847-856.
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Anthony R. Mato, Tatyana Feldman & André Goy. (2012) Proteasome Inhibition and Combination Therapy for Non-Hodgkin's Lymphoma: From Bench to Bedside. The Oncologist 17:5, pages 694-707.
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Sergio Cortelazzo, Maurilio Ponzoni, Andrés J.M. Ferreri & Martin Dreyling. (2012) Mantle cell lymphoma. Critical Reviews in Oncology/Hematology 82:1, pages 78-101.
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William Renwick. 2012. Twenty Years of G-CSF. Twenty Years of G-CSF 225 247 .
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Stéphanie Harel, Richard Delarue, Vincent Ribrag, Martin Dreyling & Olivier Hermine. (2011) Treatment of Younger Patients With Mantle Cell Lymphoma. Seminars in Hematology 48:3, pages 194-207.
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Qing-Fang Li, Jun Yan, Kai Zhang, Yue-Feng Yang, Feng-Jun Xiao, Chu-Tse Wu, Hua Wang & Li-Sheng Wang. (2011) Bortezomib and sphingosine kinase inhibitor interact synergistically to induces apoptosis in BCR/ABl+ cells sensitive and resistant to STI571 through down-regulation Mcl-1. Biochemical and Biophysical Research Communications 405:1, pages 31-36.
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Andre Goy. 2011. Bortezomib in the Treatment of Multiple Myeloma. Bortezomib in the Treatment of Multiple Myeloma 107 121 .
Patrick B Johnston, RuiRong Yuan, Franco Cavalli & Thomas E Witzig. (2010) Targeted therapy in lymphoma. Journal of Hematology & Oncology 3:1.
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Martin Dreyling & Wolfgang Hiddemann. (2009) Current treatment standards and emerging strategies in mantle cell lymphoma. Hematology 2009:1, pages 542-551.
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