Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

Davis M. SeeligDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA; ;Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA;

Daisuke ItoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA; ;Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA;

Colleen L. ForsterThe University of Minnesota Biological Materials Procurement Network (BioNet), University of Minnesota, Minneapolis, MN, USA;

Una A. YoonDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA;

Matthew BreenDepartment of Molecular Biomedical Sciences, College of Veterinary Medicine, Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, NC, USA; ;Cancer Genetics Program, University of North Carolina Lineberger Comprehensive Cancer Center, Raleigh, NC, USA;

Linda J. BurnsMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; ;Department of Medicine, Division of Hematology, Oncology, and Transplantation, School of Medicine, University of Minnesota, Minneapolis, MN, USA;

Veronika BachanovaMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; ;Department of Medicine, Division of Hematology, Oncology, and Transplantation, School of Medicine, University of Minnesota, Minneapolis, MN, USA;

Kerstin Lindblad-TohBroad Institute of MIT and Harvard, Cambridge, MA, USA; ;Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden;

Timothy D. O’BrienDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA; ;Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA;

Stephen C. SchmechelDepartment of Pathology, University of Washington, Seattle, WA, USA;

Anthony E. RizzardiDepartment of Pathology, University of Washington, Seattle, WA, USA;

Jaime F. ModianoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA; ;Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; ;Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA; ;Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA; ;Center for Immunology, University of Minnesota, Minneapolis, MN, USA;

Michael A. LindenMasonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; ;Department of Laboratory Medicine and Pathology, Division of Hematopathology, School of Medicine, University of Minnesota, Minneapolis, MN, USACorrespondence[email protected]

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Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

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Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

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