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Research Article

Potential of calcium pectinate beads for target specific drug release to colon

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Pages 285-294 | Received 13 Aug 2006, Accepted 29 Nov 2006, Published online: 08 Oct 2008

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Read on this site (10)

Niranjan G Kotla, Sima Singh, Balaji Maddiboyina, Omprakash Sunnapu & Thomas J Webster. (2016) A novel dissolution media for testing drug release from a nanostructured polysaccharide-based colon specific drug delivery system: an approach to alternative colon media. International Journal of Nanomedicine 11, pages 1089-1095.
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Anekant Jain & Sanjay K. Jain. (2016) Optimization of chitosan nanoparticles for colon tumors using experimental design methodology. Artificial Cells, Nanomedicine, and Biotechnology 44:8, pages 1917-1926.
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Lin Zhang, Yuan Sang, Jing Feng, Zhaoming Li & Aili Zhao. (2016) Polysaccharide-based micro/nanocarriers for oral colon-targeted drug delivery. Journal of Drug Targeting 24:7, pages 579-589.
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Xiuli Wei, Yi Lu, Jianping Qi, Baojian Wu, Jian Chen, Huinan Xu & Wei Wu. (2015) An in situ crosslinked compression coat comprised of pectin and calcium chloride for colon-specific delivery of indomethacin. Drug Delivery 22:3, pages 298-305.
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Kiran Chaturvedi, Santosh Kumar Tripathi, Anandrao R. Kulkarni & Tejraj M. Aminabhavi. (2013) Cytotoxicity and antitumour activity of 5-fluorouracil-loaded polyhydroxybutyrate and cellulose acetate phthalate blend microspheres. Journal of Microencapsulation 30:4, pages 356-368.
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Anima Vats & Kamla Pathak. (2013) Exploiting microspheres as a therapeutic proficient doer for colon delivery: a review. Expert Opinion on Drug Delivery 10:4, pages 545-557.
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Thiruganesh Ramasamy, Hima Bindu Ruttala, Suresh Shanmugam & Subbiah Kandasamy Umadevi. (2013) Eudragit-coated aceclofenac-loaded pectin microspheres in chronopharmacological treatment of rheumatoid arthritis. Drug Delivery 20:2, pages 65-77.
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Yellela S. R. Krishnaiah & Mansoor A. Khan. (2012) Strategies of targeting oral drug delivery systems to the colon and their potential use for the treatment of colorectal cancer. Pharmaceutical Development and Technology 17:5, pages 521-540.
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Fengliang Cao, Buyun Ding, Min Sun, Chenyu Guo, Lin Zhang & Guangxi Zhai. (2011) Lung-targeted delivery system of curcumin loaded gelatin microspheres. Drug Delivery 18:8, pages 545-554.
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Nitesh Shah, Tejal Shah & Avani Amin. (2011) Polysaccharides: a targeting strategy for colonic drug delivery. Expert Opinion on Drug Delivery 8:6, pages 779-796.
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Articles from other publishers (35)

Samia Farhaj, Theodora L. Agbotui, Jorabar Singh Nirwan, Qaisar Mahmood, Abid Mehmood Yousaf, Talib Hussain, Yasser Shahzad, Nemat Khan, Barbara R. Conway & Muhammad Usman Ghori. (2022) Carbohydrate Polymer-Based Targeted Pharmaceutical Formulations for Colorectal Cancer: Systematic Review of the Literature. Polysaccharides 3:4, pages 692-714.
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Constantinos Markopoulos & Maria Vertzoni. 2022. Oral Drug Delivery for Modified Release Formulations. Oral Drug Delivery for Modified Release Formulations 305 324 .
Surajit Das. (2021) Pectin based multi-particulate carriers for colon-specific delivery of therapeutic agents. International Journal of Pharmaceutics 605, pages 120814.
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Glenn Lemmens, Arno Van Camp, Stephanie Kourula, Tim Vanuytsel & Patrick Augustijns. (2021) Drug Disposition in the Lower Gastrointestinal Tract: Targeting and Monitoring. Pharmaceutics 13:2, pages 161.
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Baljit Singh & Baldev Singh. (2021) Design of dietary fiber azadiracta indica gum based hydrogels for use in drug delivery. Food Hydrocolloids for Health 1, pages 100011.
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Nitin Sharma, Ritu Karwasra & Gaurav Kumar Jain. 2021. Advanced Drug Delivery Systems in the Management of Cancer. Advanced Drug Delivery Systems in the Management of Cancer 259 266 .
Amit Kumar Nayak, Md Saquib Hasnain & Dilipkumar Pal. 2021. Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery. Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery 1 28 .
M. Khotimchenko. (2020) Pectin polymers for colon-targeted antitumor drug delivery. International Journal of Biological Macromolecules 158, pages 1110-1124.
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Dhanabal Kumarasamy & Tapan Kumar Giri. 2019. Polysaccharide Carriers for Drug Delivery. Polysaccharide Carriers for Drug Delivery 585 613 .
Geet P. Asnani & Chandrakant R. Kokare. (2018) In vitro and in vivo evaluation of colon cancer targeted epichlorohydrin crosslinked Portulaca-alginate beads. Biomolecular Concepts 9:1, pages 190-199.
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V. V. Golotiuk. (2018) PROSPECTS OF APPLICATION OF PECTIN MODIFICATIONS IN THE COMPLEX MEDICAMENT THERAPY OF COLORECTAL CANCER. Bulletin of Problems Biology and Medicine 1.1:142, pages 25.
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Marwa I. Wahba. (2017) Chitosan-glutaraldehyde activated calcium pectinate beads as a covalent immobilization support. Biocatalysis and Agricultural Biotechnology 12, pages 266-274.
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Adel Penhasi. (2017) Preparation and characterization of in-situ ionic cross-linked pectin films: II. Biodegradation and drug diffusion. Carbohydrate Polymers 157, pages 651-659.
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Chityal Ganesh Kumar, Yedla Poornachandra & Sujitha Pombala. 2017. Nanostructures for Drug Delivery. Nanostructures for Drug Delivery 1 61 .
Hui Li Tan, Li Shan Tan, Yeon Yin Wong, Saravanan Muniyandy, Kamaruddin Hashim & Janarthanan Pushpamalar. (2016) Dual crosslinked carboxymethyl sago pulp/pectin hydrogel beads as potential carrier for colon-targeted drug delivery. Journal of Applied Polymer Science 133:19, pages n/a-n/a.
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Siddhartha Maity & Biswanath Sa. (2015) Compression-Coated Tablet for Colon Targeting: Impact of Coating and Core Materials on Drug Release. AAPS PharmSciTech 17:2, pages 504-515.
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Arvind Gulbake. (2016) Insight to drug delivery aspects for colorectal cancer. World Journal of Gastroenterology 22:2, pages 582.
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Ankita Gupta, Gaurav Tiwari, Ruchi Tiwari, Rishabh Srivastava & A. K. Rai. (2015) Enteric coated HPMC capsules plugged with 5-FU loaded microsponges: a potential approach for treatment of colon cancer. Brazilian Journal of Pharmaceutical Sciences 51:3, pages 591-605.
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Xiujun Guo, Hanying Duan, Chao Wang & Xuesong Huang. (2014) Characteristics of Two Calcium Pectinates Prepared from Citrus Pectin Using Either Calcium Chloride or Calcium Hydroxide. Journal of Agricultural and Food Chemistry 62:27, pages 6354-6361.
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Niranjan Goud Kotla, Monica Gulati, Sachin Kumar Singh & Ashwini Shivapooja. (2014) Facts, fallacies and future of dissolution testing of polysaccharide based colon-specific drug delivery. Journal of Controlled Release 178, pages 55-62.
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Rajiv Sharma, Ravindra K. Rawal, Manav Malhotra, A.K. Sharma & T.R. Bhardwaj. (2014) Design, synthesis and ex-vivo release studies of colon-specific polyphosphazene–anticancer drug conjugates. Bioorganic & Medicinal Chemistry 22:3, pages 1104-1114.
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Rajiv Sharma, Ravindra K. Rawal, Tripti Gaba, Nishu Singla, Manav Malhotra, Sahil Matharoo & T.R. Bhardwaj. (2013) Design, synthesis and ex vivo evaluation of colon-specific azo based prodrugs of anticancer agents. Bioorganic & Medicinal Chemistry Letters 23:19, pages 5332-5338.
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Carmen Alvarez-Lorenzo, Barbara Blanco-Fernandez, Ana M. Puga & Angel Concheiro. (2013) Crosslinked ionic polysaccharides for stimuli-sensitive drug delivery. Advanced Drug Delivery Reviews 65:9, pages 1148-1171.
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Mohammad Zaki Ahmad, Sohail Akhter, Mohammed Anwar & Farhan Jalees Ahmad. (2012) Assam Bora Rice Starch Based Biocompatible Mucoadhesive Microsphere for Targeted Delivery of 5-Fluorouracil in Colorectal Cancer. Molecular Pharmaceutics 9:11, pages 2986-2994.
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Rishabh Srivastava, Deepesh Kumar & Kamla Pathak. (2012) Colonic luminal surface retention of meloxicam microsponges delivered by erosion based colon-targeted matrix tablet. International Journal of Pharmaceutics 427:2, pages 153-162.
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Tin Wui Wong, Gaia Colombo & Fabio Sonvico. (2010) Pectin Matrix as Oral Drug Delivery Vehicle for Colon Cancer Treatment. AAPS PharmSciTech 12:1, pages 201-214.
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Surajit Das, Anumita Chaudhury & Ka-Yun Ng. (2011) Preparation and evaluation of zinc–pectin–chitosan composite particles for drug delivery to the colon: Role of chitosan in modifying in vitro and in vivo drug release. International Journal of Pharmaceutics 406:1-2, pages 11-20.
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Mirela Nadler Milabuer, Yossi Kam & Abraham Rubinstein. 2010. Oral Controlled Release Formulation Design and Drug Delivery. Oral Controlled Release Formulation Design and Drug Delivery 225 243 .
Ziyaur Rahman, Kanchan Kohli, Shuang-Qing Zhang, Roop K Khar, Mushir Ali, Naseem A Charoo, Mohammad Tauseef, Areeg A A Shamsher, Noorullah N Mohammed & Michael A Repka. (2008) In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil. Journal of Pharmacy and Pharmacology 60:5, pages 615-623.
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Anekant Jain, Sanjay K. Jain, N. Ganesh, Jaya Barve & Aadil M. Beg. (2010) Design and development of ligand-appended polysaccharidic nanoparticles for the delivery of oxaliplatin in colorectal cancer. Nanomedicine: Nanotechnology, Biology and Medicine 6:1, pages 179-190.
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Anekant Jain & Sanjay K. Jain. (2008) In vitro and cell uptake studies for targeting of ligand anchored nanoparticles for colon tumors. European Journal of Pharmaceutical Sciences 35:5, pages 404-416.
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Tetsuya Adachi, Hiroyuki Yanaka, Hitoshi Kanai, Mayu Nozaki, Yoshiyuki Takahara, Mariko Tsuda, Tatsuya Jonouchi, Kinsuke Tsuda, Akira Hirasawa & Gozoh Tsujimoto. (2008) Administration of Perilla Oil Coated with Calshell Increases Glucagon-Like Peptide Secretion. Biological & Pharmaceutical Bulletin 31:5, pages 1021-1023.
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Libo Yang. (2008) Biorelevant dissolution testing of colon-specific delivery systems activated by colonic microflora. Journal of Controlled Release 125:2, pages 77-86.
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S.K. Jain, A. Jain, Y. Gupta, A. Jain, P. Khare & M. Kannandasan. (2008) Targeted delivery of 5-ASA to colon using chitosan hydrogel microspheres. Journal of Drug Delivery Science and Technology 18:5, pages 315-321.
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Sanjay K. Jain, Anekant Jain, Yashwant Gupta & Manisha Ahirwar. (2007) Design and development of hydrogel beads for targeted drug delivery to the colon. AAPS PharmSciTech 8:3, pages E34-E41.
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