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Journal of Drug Targeting Volume 15, 2007 - Issue 4
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Research Article

Bio-distribution and anti-tumor efficacy of PEG/PLA nano particles loaded doxorubicin

J. J. Yu Medical Nano Element Development Center, Samsung Medical Center, Seoul, South Korea
,
H. A. Lee Division of Hematology–Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, South Korea
,
J. H. Kim Biomedical Engineering Interdisciplinary Course, Sungkyunkwan University School of Medicine, Suwon, South Korea
,
W. H. Kong Biomedical Engineering Interdisciplinary Course, Sungkyunkwan University School of Medicine, Suwon, South Korea
,
Y. Kim Division of Hematology–Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, South Korea
,
Z. Y. Cui Medical Nano Element Development Center, Samsung Medical Center, Seoul, South Korea
,
K. G. Park Division of Hematology–Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, South Korea
,
W. S. Kim Division of Hematology–Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, South Korea
,
H. G. Lee Division of Hematology–Oncology, KunKook University School of Medicine, Seoul, South Korea
&
S. W. Seo Biomedical Engineering Interdisciplinary Course, Sungkyunkwan University School of Medicine, Suwon, South Korea
 show all
Pages 279-284 | Received 06 Dec 2006, Accepted 19 Mar 2007, Published online: 08 Oct 2008

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Jingyi Zhou, Kangkang Li, Xinlong Zang, Yi Xie, Jinxiao Song & Xuehong Chen. (2023) ROS-responsive Galactosylated-nanoparticles with Doxorubicin Entrapment for Triple Negative Breast Cancer Therapy. International Journal of Nanomedicine 18, pages 1381-1397.
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Lu Zhang, Jiafei Lu & Liyan Qiu. (2016) Synergistic effects of A-B-C-type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma. International Journal of Nanomedicine 11, pages 5205-5220.
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AiHua Lin, Jun Chen, YiMing Liu, Shigui Deng, Zhifeng Wu, Yu Huang & QiNeng Ping. (2009) Preparation and evaluation of N-caproyl chitosan nanoparticles surface modified with glycyrrhizin for hepatocyte targeting. Drug Development and Industrial Pharmacy 35:11, pages 1348-1355.
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Movva Snehalatha, Kolachina Venugopal, Ranendra N. Saha, Anil Kumar Babbar & Rakesh Kumar Sharma. (2008) Etoposide Loaded PLGA and PCL Nanoparticles II: Biodistribution and Pharmacokinetics after Radiolabeling with Tc-99m. Drug Delivery 15:5, pages 277-287.
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Mayur Aalhate, Srushti Mahajan, Hoshiyar Singh, Santosh Kumar Guru & Pankaj Kumar Singh. (2023) Nanomedicine in therapeutic warfront against estrogen receptor–positive breast cancer. Drug Delivery and Translational Research 13:6, pages 1621-1653.
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Mohamad Mahani, Maryam Pourrahmani-Sarbanani, Mehdi Yoosefian, Faten Divsar, Seyedeh Maral Mousavi & Alireza Nomani. (2021) Doxorubicin delivery to breast cancer cells with transferrin-targeted carbon quantum dots: An in vitro and in silico study. Journal of Drug Delivery Science and Technology 62, pages 102342.
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Jing Chang, Zhe Yang, Junfeng Li, Yufen Jin, Yihang Gao, Yanwen Sun, Hainan Li & Ting Yu. (2020) Preparation and In Vitro and In Vivo Antitumor Effects of VEGF Targeting Micelles. Technology in Cancer Research & Treatment 19, pages 153303382095702.
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Marzena Szwed, Katarzyna D. Kania & Zofia Jozwiak. (2014) Relationship between therapeutic efficacy of doxorubicin-transferrin conjugate and expression of P-glycoprotein in chronic erythromyeloblastoid leukemia cells sensitive and resistant to doxorubicin. Cellular Oncology 37:6, pages 421-428.
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Lu Zhang, Jiafei Lu, Yangmin Jin & Liyan Qiu. (2014) Folate-conjugated beta-cyclodextrin-based polymeric micelles with enhanced doxorubicin antitumor efficacy. Colloids and Surfaces B: Biointerfaces 122, pages 260-269.
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Boyu Zhang, Hong Zhang, Yejia Li, Jessica N. Hoskins & Scott M. Grayson. (2013) Exploring the Effect of Amphiphilic Polymer Architecture: Synthesis, Characterization, and Self-Assembly of Both Cyclic and Linear Poly(ethylene gylcol)- b -polycaprolactone . ACS Macro Letters 2:10, pages 845-848.
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A. Cambón, J. Brea, M. I. Loza, C. Alvarez-Lorenzo, A. Concheiro, S. Barbosa, P. Taboada & V. Mosquera. (2013) Cytocompatibility and P-glycoprotein Inhibition of Block Copolymers: Structure–Activity Relationship. Molecular Pharmaceutics 10:8, pages 3232-3241.
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A. V. Murueva, E. I. Shishatskaya, A. M. Kuzmina, T. G. Volova & A. J. Sinskey. (2013) Microparticles prepared from biodegradable polyhydroxyalkanoates as matrix for encapsulation of cytostatic drug. Journal of Materials Science: Materials in Medicine 24:8, pages 1905-1915.
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Movva Snehalatha, Venugopal Kolachina, RanendraNarayan Saha, AnilKumar Babbar, Navneet Sharma & RakeshKumar Sharma. (2013) Enhanced tumor uptake, biodistribution and pharmacokinetics of etoposide loaded nanoparticles in Dalton′s lymphoma tumor bearing mice. Journal of Pharmacy And Bioallied Sciences 5:4, pages 290.
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Eun Seong Lee, Chaemin Lim, Ho-Taek Song, Jeong Min Yun, Kyung Soo Lee, Beom-Jin Lee, Yu Seok Youn, Young Taik Oh & Kyung Teak Oh. (2012) A nanosized delivery system of superparamagnetic iron oxide for tumor MR imaging. International Journal of Pharmaceutics 439:1-2, pages 342-348.
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Chuangnian Zhang, Wei Wang, Tong Liu, Yukun Wu, Hua Guo, Ping Wang, Qin Tian, Yongming Wang & Zhi Yuan. (2012) Doxorubicin-loaded glycyrrhetinic acid-modified alginate nanoparticles for liver tumor chemotherapy. Biomaterials 33:7, pages 2187-2196.
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Ming-Jium Shieh, Chia-Yen Hsu, Ling-Yi Huang, Hsuan-Ying Chen, Fei-Hong Huang & Ping-Shan Lai. (2011) Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells. Journal of Controlled Release 152:3, pages 418-425.
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Shivaram SelvamWenji V. ChangTamako NakamuraDeedar M. SamantPadmaja B. ThomasMelvin D. TrousdaleAustin K. MircheffJoel E. SchechterSamuel C. Yiu. (2009) Microporous Poly(L-Lactic Acid) Membranes Fabricated by Polyethylene Glycol Solvent-Cast/Particulate Leaching Technique. Tissue Engineering Part C: Methods 15:3, pages 463-474.
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Savita Bisht & Amarnath Maitra. (2009) Dextran–doxorubicin/chitosan nanoparticles for solid tumor therapy. WIREs Nanomedicine and Nanobiotechnology 1:4, pages 415-425.
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Yen Cu & W. Mark Saltzman. (2008) Controlled Surface Modification with Poly(ethylene)glycol Enhances Diffusion of PLGA Nanoparticles in Human Cervical Mucus. Molecular Pharmaceutics 6:1, pages 173-181.
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DeeDee Smith, Sandra H. Clark, Paul A. Bertin, Bernard L. Mirkin & SonBinh T. Nguyen. (2009) Synthesis and in vitro activity of ROMP-based polymer nanoparticles. Journal of Materials Chemistry 19:15, pages 2159.
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Ales Prokop & Jeffrey M. Davidson. (2008) Nanovehicular Intracellular Delivery Systems. Journal of Pharmaceutical Sciences 97:9, pages 3518-3590.
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