Advanced search
Publication Cover
Journal of Drug Targeting Volume 16, 2008 - Issue 9
Submit an article Journal homepage
220
Views
41
CrossRef citations to date
0
Altmetric
Research Article

Selective delivery of folate–PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: Effect of chain length and amount of folate–PEG linker

Yukino Ohguchi Institute of Medicinal Chemistry, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, Japan
,
Kumi Kawano Institute of Medicinal Chemistry, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, Japan
,
Yoshiyuki Hattori Institute of Medicinal Chemistry, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, Japan
&
Yoshie Maitani Institute of Medicinal Chemistry, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, JapanCorrespondence[email protected]
Pages 660-667 | Received 05 Feb 2008, Accepted 14 May 2008, Published online: 03 Dec 2008

Citations (41)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Chaemin Lim, Yuseon Shin, Kioh Kang, Patihul Husni, Dayoon Lee, Sehwa Lee, Han-Gon Choi, Eun Seong Lee, Yu Seok Youn & Kyung Taek Oh. (2023) Effects of PEG-Linker Chain Length of Folate-Linked Liposomal Formulations on Targeting Ability and Antitumor Activity of Encapsulated Drug. International Journal of Nanomedicine 18, pages 1615-1630.
Read now
L. P. Icart, Edson R. F. Santos, L. Agüero, Leonardo R. Andrade, C. G. de Souza, L. A. d´Avila, D. Zaldivar & M. L. Dias. (2018) Paclitaxel-loaded PLA/PEG/fluorescein anticancer agent prepared by Ugi reaction. International Journal of Polymeric Materials and Polymeric Biomaterials 67:13, pages 776-782.
Read now
Cai-Xia He, Zhong-Gui He & Jian-Qing Gao. (2010) Microemulsions as drug delivery systems to improve the solubility and the bioavailability of poorly water-soluble drugs. Expert Opinion on Drug Delivery 7:4, pages 445-460.
Read now

Articles from other publishers (38)

Riddhi Vichare, Caitlin Crelli, Lu Liu, Rebecca McCallin, Abree Cowan, Stefan Stratimirovic, Michele Herneisey, John A. Pollock & Jelena M. Janjic. (2023) Folate-conjugated near-infrared fluorescent perfluorocarbon nanoemulsions as theranostics for activated macrophage COX-2 inhibition. Scientific Reports 13:1.
Crossref
Shristi Kishore, Shradha A. Kumar, Tridib Roy, Abhaya Bhardwaj & Sumira Malik. 2022. Advancements in Controlled Drug Delivery Systems. Advancements in Controlled Drug Delivery Systems 44 72 .
Sumira Malik, Shristi Kishore, Manisha Kumari & Archna Dhasmana. 2022. Handbook of Research on Nanoemulsion Applications in Agriculture, Food, Health, and Biomedical Sciences. Handbook of Research on Nanoemulsion Applications in Agriculture, Food, Health, and Biomedical Sciences 237 259 .
Areen M. Khattabi & Nouf N. Mahmoud. (2021) Interaction of folate – Linked silica nanoparticles with HeLa cells: Analysis and investigation the effect of polymer length. Saudi Pharmaceutical Journal 29:10, pages 1083-1089.
Crossref
Liwang Shi, Jinqiu Zhang, Man Zhao, Shukun Tang, Xu Cheng, Wenyuan Zhang, Wenhua Li, Xiaoying Liu, Haisheng Peng & Qun Wang. (2021) Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery. Nanoscale 13:24, pages 10748-10764.
Crossref
Mohamed F. Attia, Maria I. Swasy, Roman Akasov, Frank Alexis & Daniel C. Whitehead. (2020) Strategies for High Grafting Efficiency of Functional Ligands to Lipid Nanoemulsions for RGD-Mediated Targeting of Tumor Cells In Vitro . ACS Applied Bio Materials 3:8, pages 5067-5079.
Crossref
Dinglin Zhang & Jianxiang Zhang. (2020) Surface engineering of nanomaterials with phospholipid-polyethylene glycol-derived functional conjugates for molecular imaging and targeted therapy. Biomaterials 230, pages 119646.
Crossref
Akhtar, Ghali, Wang, Bell, Li & Wen. (2019) Optimisation of Folate-Mediated Liposomal Encapsulated Arsenic Trioxide for Treating HPV-Positive Cervical Cancer Cells In Vitro. International Journal of Molecular Sciences 20:9, pages 2156.
Crossref
Areen M. Khattabi, Wamidh H. Talib & Diala A. Alqdeimat. (2018) The effect of polymer length on the in vitro characteristics of a drug loaded and targeted silica nanoparticles. Saudi Pharmaceutical Journal 26:7, pages 1022-1026.
Crossref
Hossam H Tayeb & Frank Sainsbury. (2018) Nanoemulsions in drug delivery: formulation to medical application. Nanomedicine 13:19, pages 2507-2525.
Crossref
Trang Huyen Le Kim, Hwiseok Jun, Jin Ho Kim, Keunchil Park, Jee Seon Kim & Yoon Sung Nam. (2017) Lipiodol nanoemulsions stabilized with polyglycerol-polycaprolactone block copolymers for theranostic applications. Biomaterials Research 21:1.
Crossref
Victoria Mico, Antonia Charalambous, Sally A. Peyman, Radwa H. Abou-Saleh, Alexander F. Markham, P. Louise Coletta & Stephen D. Evans. (2017) Evaluation of lipid-stabilised tripropionin nanodroplets as a delivery route for combretastatin A4. International Journal of Pharmaceutics 526:1-2, pages 547-555.
Crossref
Muhammad Raza Shah, Muhammad Imran & Shafi Ullah. 2017. Lipid-Based Nanocarriers for Drug Delivery and Diagnosis. Lipid-Based Nanocarriers for Drug Delivery and Diagnosis 111 137 .
Roya Biabanikhankahdani, Noorjahan Banu Mohamed Alitheen, Kok Lian Ho & Wen Siang Tan. (2016) pH-responsive Virus-like Nanoparticles with Enhanced Tumour-targeting Ligands for Cancer Drug Delivery. Scientific Reports 6:1.
Crossref
Mihue Jang, Hee Dong Han & Hyung Jun Ahn. (2016) A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy. Scientific Reports 6:1.
Crossref
Syed Muzammil Afzal, Mohammad Zubair Shareef, Tummuri Dinesh & Veerabrahma Kishan. (2016) Folate-PEG-decorated docetaxel lipid nanoemulsion for improved antitumor activity. Nanomedicine 11:16, pages 2171-2184.
Crossref
Shuai‑Jun Chen, Hong‑Zheng Zhang, Liang‑Cai Wan, Shan‑Shan Jiang, Yi‑Ming Xu, Fang Liu, Tao Zhang, Dong Ma & Min‑Qiang Xie. (2016) Preparation and performance of a pH-sensitive cisplatin-loaded magnetic nanomedicine that targets tumor cells via folate receptor mediation. Molecular Medicine Reports.
Crossref
Luis P. Icart, Edson Fernandes, Lissette Agüero, Jose Ramón, Dionisio Zaldivar & Marcos L. Dias. (2016) Fluorescent microspheres of poly(ethylene glycol)-poly(lactic acid)-fluorescein copolymers synthesized by Ugi four-component condensation. Journal of Applied Polymer Science 133:9, pages n/a-n/a.
Crossref
Sushama Talegaonkar & Lalit Mohan Negi. 2015. Targeted Drug Delivery : Concepts and Design. Targeted Drug Delivery : Concepts and Design 433 459 .
Gregory Nkepang, Moses Bio, Pallavi Rajaputra, Samuel G. Awuah & Youngjae You. (2014) Folate Receptor-Mediated Enhanced and Specific Delivery of Far-Red Light-Activatable Prodrugs of Combretastatin A-4 to FR-Positive Tumor. Bioconjugate Chemistry 25:12, pages 2175-2188.
Crossref
Charlene M. Dawidczyk, Luisa M. Russell & Peter C. Searson. (2014) Nanomedicines for cancer therapy: state-of-the-art and limitations to pre-clinical studies that hinder future developments. Frontiers in Chemistry 2.
Crossref
Hui Jiang & Xuemei Wang. (2014) Label-Free Detection of Folate Receptor (+) Cells by Molecular Recognition Mediated Electrochemiluminescence of CdTe Nanoparticles. Analytical Chemistry 86:14, pages 6872-6878.
Crossref
Srinivas Ganta, Meghna Talekar, Amit Singh, Timothy P. Coleman & Mansoor M. Amiji. (2014) Nanoemulsions in Translational Research—Opportunities and Challenges in Targeted Cancer Therapy. AAPS PharmSciTech 15:3, pages 694-708.
Crossref
Frank Sainsbury, Bijun Zeng & Anton PJ Middelberg. (2014) Towards designer nanoemulsions for precision delivery of therapeutics. Current Opinion in Chemical Engineering 4, pages 11-17.
Crossref
Erina Vlashi, Lindsay E. Kelderhouse, Jennifer E. Sturgis & Philip S. Low. (2013) Effect of Folate-Targeted Nanoparticle Size on Their Rates of Penetration into Solid Tumors. ACS Nano 7:10, pages 8573-8582.
Crossref
Koldo Urbiola, Leire García, Sara Zalba, María J. Garrido & Conchita Tros de Ilarduya. (2013) Efficient serum-resistant lipopolyplexes targeted to the folate receptor. European Journal of Pharmaceutics and Biopharmaceutics 83:3, pages 358-363.
Crossref
Aleksander Mendyk, Jakub Szlȩk & Renata Jachowicz. 2013. Formulation Tools for Pharmaceutical Development. Formulation Tools for Pharmaceutical Development 39 71 .
M. Mazza, M. Alonso-Sande, M.-C. Jones & M. de la Fuente. 2013. Fundamentals of Pharmaceutical Nanoscience. Fundamentals of Pharmaceutical Nanoscience 117 158 .
Patricia M. LoRussoMartin J. EdelmanSusan L. BeverKaren M. FormanMaryJo PilatMary F. QuinnJing LiElisabeth I. HeathLisa M. MalburgPatrick J. KleinChristopher P. LeamonRichard A. MessmannEdward A. Sausville. (2012) Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors. Journal of Clinical Oncology 30:32, pages 4011-4016.
Crossref
Meghna Talekar, Srinivas Ganta, Amit Singh, Mansoor Amiji, Jackie Kendall, William A. Denny & Sanjay Garg. (2012) Phosphatidylinositol 3-kinase Inhibitor (PIK75) Containing Surface Functionalized Nanoemulsion for Enhanced Drug Delivery, Cytotoxicity and Pro-apoptotic Activity in Ovarian Cancer Cells. Pharmaceutical Research 29:10, pages 2874-2886.
Crossref
Minqiang Xie, Yiming Xu, Jie Liu, Tao Zhang & Hongzheng Zhang. (2012) Preparation and Characterization of Folate Targeting Magnetic Nanomedicine Loaded with Cisplatin. Journal of Nanomaterials 2012, pages 1-9.
Crossref
Nazila Kamaly, Zeyu Xiao, Pedro M. Valencia, Aleksandar F. Radovic-Moreno & Omid C. Farokhzad. (2012) Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chemical Society Reviews 41:7, pages 2971.
Crossref
Meghna Talekar, Jackie Kendall, William Denny & Sanjay Garg. (2011) Targeting of nanoparticles in cancer. Anti-Cancer Drugs 22:10, pages 949-962.
Crossref
Yoshie Maitani. (2011) Biodistribution and Transfer of Functional PEGylated Lipid-based Particles to Cancer Cells. MEMBRANE 36:4, pages 154-162.
Crossref
Y. Maitani. (2011) PEGylated lipidic systems with prolonged circulation longevity for drug delivery in cancer therapeutics. Journal of Drug Delivery Science and Technology 21:1, pages 27-34.
Crossref
Ying Wang, Yiqing Wang, Jiannan Xiang & Kaitai Yao. (2010) Target-Specific Cellular Uptake of Taxol-Loaded Heparin-PEG-Folate Nanoparticles. Biomacromolecules 11:12, pages 3531-3538.
Crossref
Himanshu Bhattacharjee, Pavan Balabathula & George C Wood. (2010) Targeted nanoparticulate drug-delivery systems for treatment of solid tumors: a review. Therapeutic Delivery 1:5, pages 713-734.
Crossref
Yoshiyuki HATTORI. (2010) Development of Non-viral Vector for Cancer Gene Therapyがん遺伝子治療のための非ウイルスベクターの開発. YAKUGAKU ZASSHI 130:7, pages 917-923.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.