398
Views
35
CrossRef citations to date
0
Altmetric
Research Article

RGD-modified polymeric micelles as potential carriers for targeted delivery to integrin-overexpressing tumor vasculature and tumor cells

, , , , , & show all
Pages 459-467 | Received 22 Feb 2009, Accepted 16 Apr 2009, Published online: 19 May 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Joseph G. Altin & Yabing Zhao. (2022) Using peptides to promote delivery and improve anti-tumour efficacy of liposomal drug. Journal of Drug Targeting 30:5, pages 544-556.
Read now
Gang Li, Yan-zhi Song, Zhen-jun Huang, Kang Chen, Da-wei Chen & Yi-hui Deng. (2017) Novel, nano-sized, liposome-encapsulated polyamidoamine dendrimer derivatives facilitate tumour targeting by overcoming the polyethylene glycol dilemma and integrin saturation obstacle. Journal of Drug Targeting 25:8, pages 734-746.
Read now
T. S. Anirudhan, J. Parvathy & Anoop S. Nair. (2016) Evaluation of micellar architecture based on functionalized chitosan for the in vitro release of an antibiotic. Designed Monomers and Polymers 19:2, pages 99-107.
Read now
April Raj, Poonam Saraf, Narashima Murthy Javali, Xiaoling Li & Bhaskara Jasti. (2014) Binding and uptake of novel RGD micelles to the αvβ3 integrin receptor for targeted drug delivery. Journal of Drug Targeting 22:6, pages 518-527.
Read now
Jie Yin, Zaiquan Li, Tingyuan Yang, Jiancheng Wang, Xuan Zhang & Qiang Zhang. (2011) Cyclic RGDyK conjugation facilitates intracellular drug delivery of polymeric micelles to integrin-overexpressing tumor cells and neovasculature. Journal of Drug Targeting 19:1, pages 25-36.
Read now
Wenbing Dai, Tingyuan Yang, Xueqing Wang, Jiancheng Wang, Xuan Zhang & Qiang Zhang. (2010) PHSCNK-Modified and doxorubicin-loaded liposomes as a dual targeting system to integrin-overexpressing tumor neovasculature and tumor cells. Journal of Drug Targeting 18:4, pages 254-263.
Read now

Articles from other publishers (29)

Valentina Pirota, Giovanni Bisbano, Massimo Serra, Maria Luisa Torre, Filippo Doria, Elia Bari & Mayra Paolillo. (2023) cRGD-Functionalized Silk Fibroin Nanoparticles: A Strategy for Cancer Treatment with a Potent Unselective Naphthalene Diimide Derivative. Cancers 15:6, pages 1725.
Crossref
Jingyuan Wei. (2022) Nano-medicine in Treating Reumatoid Arthritics. Highlights in Science, Engineering and Technology 2, pages 186-199.
Crossref
Bixi Sun, Shuwen Liu, Rubin Hao, Xinyue Dong, Lanbo Fu & Bing Han. (2020) RGD-PEG-PLA Delivers MiR-133 to Infarct Lesions of Acute Myocardial Infarction Model Rats for Cardiac Protection. Pharmaceutics 12:6, pages 575.
Crossref
Diego Tesauro, Antonella Accardo, Carlo Diaferia, Vittoria Milano, Jean Guillon, Luisa Ronga & Filomena Rossi. (2019) Peptide-Based Drug-Delivery Systems in Biotechnological Applications: Recent Advances and Perspectives. Molecules 24:2, pages 351.
Crossref
Thayyath Sreenivasan Anirudhan & Jayasree Parvathy. (2018) Novel Thiolated Chitosan-Polyethyleneglycol blend/Montmorillonite composite formulations for the oral delivery of insulin. Bioactive Carbohydrates and Dietary Fibre 16, pages 22-29.
Crossref
Boxuan Ma, Weihua Zhuang, Gongyan Liu & Yunbing Wang. (2018) A biomimetic and pH-sensitive polymeric micelle as carrier for paclitaxel delivery. Regenerative Biomaterials 5:1, pages 15-24.
Crossref
Dan Wang, Jijun Fu, Yujie Shi, Dong Peng, Lan Yuan, Bing He, Wenbing Dai, Hua Zhang, Xueqing Wang, Jie Tian & Qiang Zhang. (2016) The modulation of tumor vessel permeability by thalidomide and its impacts on different types of targeted drug delivery systems in a sarcoma mouse model. Journal of Controlled Release 238, pages 186-196.
Crossref
Poonam Saraf, Xiaoling Li, Lisa Wrischnik & Bhaskara Jasti. (2015) In Vitro and In Vivo Efficacy of Self-Assembling RGD Peptide Amphiphiles for Targeted Delivery of Paclitaxel. Pharmaceutical Research 32:9, pages 3087-3101.
Crossref
Poonam Saraf, Xiaoling Li & Bhaskara Jasti. 2018. Integrin Targeting Systems for Tumor Diagnosis and Therapy. Integrin Targeting Systems for Tumor Diagnosis and Therapy 135 155 .
Xueqing Wang, Suxin Li, Yujie Shi, Xingxing Chuan, Ji Li, Ting Zhong, Hua Zhang, Wenbing Dai, Bing He & Qiang Zhang. (2014) The development of site-specific drug delivery nanocarriers based on receptor mediation. Journal of Controlled Release 193, pages 139-153.
Crossref
Ali Mohammad Alizadeh, Sadaf Shiri & Sadaf Farsinejad. (2014) Metastasis review: from bench to bedside. Tumor Biology 35:9, pages 8483-8523.
Crossref
James D. Robertson, Nisa Patikarnmonthon, Adrian S. Joseph & Giuseppe Battaglia. 2013. Engineering Polymer Systems for Improved Drug Delivery. Engineering Polymer Systems for Improved Drug Delivery 163 188 .
Anu Stella Mathews, Sahar Ahmed, Mostafa Shahin, Afsaneh Lavasanifar & Kamaljit Kaur. (2013) Peptide Modified Polymeric Micelles Specific for Breast Cancer Cells. Bioconjugate Chemistry 24:4, pages 560-570.
Crossref
Sangbin Lee, Jiyeon Kim, Gayong Shim, Sunil Kim, Su Eun Han, Kwangmeyung Kim, Ick Chan Kwon, Yongseok Choi, Young Bong Kim, Chan-Wha Kim & Yu-Kyoung Oh. (2012) Tetraiodothyroacetic acid-tagged liposomes for enhanced delivery of anticancer drug to tumor tissue via integrin receptor. Journal of Controlled Release 164:2, pages 213-220.
Crossref
Narashima Murthy Javali, April Raj, Poonam Saraf, Xiaoling Li & Bhaskara Jasti. (2012) Fatty Acid–RGD Peptide Amphiphile Micelles as Potential Paclitaxel Delivery Carriers to αvβ3Integrin Overexpressing Tumors. Pharmaceutical Research 29:12, pages 3347-3361.
Crossref
Wenbing Dai, Tingyuan Yang, Yiguang Wang, Xueqing Wang, Jiancheng Wang, Xuan Zhang & Qiang Zhang. (2012) Peptide PHSCNK as an integrin α5β1 antagonist targets stealth liposomes to integrin-overexpressing melanoma. Nanomedicine: Nanotechnology, Biology and Medicine 8:7, pages 1152-1161.
Crossref
Yifei Zhang, Jiang Li, Xiang Gao & Song Li. 2012. Pulmonary Nanomedicine. Pulmonary Nanomedicine 193 233 .
Saijie Zhu, Dharmika S. P. Lansakara-P., Xinran Li & Zhengrong Cui. (2012) Lysosomal Delivery of a Lipophilic Gemcitabine Prodrug Using Novel Acid-Sensitive Micelles Improved Its Antitumor Activity. Bioconjugate Chemistry 23:5, pages 966-980.
Crossref
Yuling Xiao, Hao Hong, Alireza Javadi, Jonathan W. Engle, Wenjin Xu, Yunan Yang, Yin Zhang, Todd E. Barnhart, Weibo Cai & Shaoqin Gong. (2012) Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging. Biomaterials 33:11, pages 3071-3082.
Crossref
Ning Zhang & Andre F. Palmer. (2011) Liposomes surface conjugated with human hemoglobin target delivery to macrophages. Biotechnology and Bioengineering 109:3, pages 823-829.
Crossref
Mehrdad Hamidi, Mohammad‐Ali Shahbazi & Kobra Rostamizadeh. (2011) Copolymers: Efficient Carriers for Intelligent Nanoparticulate Drug Targeting and Gene Therapy. Macromolecular Bioscience 12:2, pages 144-164.
Crossref
Elias Fattal, Hervé Hillaireau, Simona Mura, Julien Nicolas & Nicolas Tsapis. 2012. Fundamentals and Applications of Controlled Release Drug Delivery. Fundamentals and Applications of Controlled Release Drug Delivery 255 288 .
Yiguang Wang, Tingyuan Yang, Xun Wang, Wenbing Dai, Jiancheng Wang, Xuan Zhang, Zaiquan Li & Qiang Zhang. (2011) Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system. Journal of Controlled Release 149:3, pages 299-306.
Crossref
Carmen Wängler , Simone Maschauer, Olaf Prante, Martin Schäfer, Ralf Schirrmacher, Peter Bartenstein, Michael Eisenhut & Björn Wängler . (2010) Multimerization of cRGD Peptides by Click Chemistry: Synthetic Strategies, Chemical Limitations, and Influence on Biological Properties. ChemBioChem 11:15, pages 2168-2181.
Crossref
Edna Cukierman & David R. Khan. (2010) The benefits and challenges associated with the use of drug delivery systems in cancer therapy. Biochemical Pharmacology 80:5, pages 762-770.
Crossref
David L. Morse & Robert J. Gillies. (2010) Molecular imaging and targeted therapies. Biochemical Pharmacology 80:5, pages 731-738.
Crossref
Yiguang Wang, Tingyuan Yang, Xun Wang, Jiancheng Wang, Xuan Zhang & Qiang Zhang. (2010) Targeted Polymeric Micelle System for Delivery of Combretastatin A4 to Tumor Vasculature In Vitro. Pharmaceutical Research 27:9, pages 1861-1868.
Crossref
Yi-fei Zhang, Jian-cheng Wang, Dong-yan Bian, Xuan Zhang & Qiang Zhang. (2010) Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A-4 and doxorubicin for tumor therapy: In vitro and in vivo studies. European Journal of Pharmaceutics and Biopharmaceutics 74:3, pages 467-473.
Crossref
R. Rathinam & Suresh K. Alahari. (2010) Important role of integrins in the cancer biology. Cancer and Metastasis Reviews 29:1, pages 223-237.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.