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Free Radical Research Volume 33, 2000 - Issue 1
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Original Article

Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation

Ayako Okado-Matsumoto Department of Biochemistry, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
,
Theingi Myint Department of Biochemistry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan
,
Junichi Fujii Department of Biochemistry, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka, 565-0871, JapanCorrespondence[email protected]
&
Naoyuki Taniguchi Department of Biochemistry, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata, 990-9585, Japan
Pages 65-73 | Received 17 Nov 1999, Published online: 07 Jul 2009

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Michael R. Gunther & Joseph A. Donahue. (2007) Bicarbonate and active site zinc modulate the self-peroxidation of bovine copper-zinc superoxide dismutase. Free Radical Research 41:9, pages 1005-1016.
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Articles from other publishers (19)

Seon Hwy Kim, So Young Jung, Kang-Woo Lee, Sun Hwa Lee, MuDan Cai, Sun-Mi Choi & Eun Jin Yang. (2013) Bee venom effects on ubiquitin proteasome system in hSOD1G85R-expressing NSC34 motor neuron cells. BMC Complementary and Alternative Medicine 13:1.
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Vikram Khipple Mulligan & Avijit Chakrabartty. (2013) Protein misfolding in the late-onset neurodegenerative diseases: Common themes and the unique case of amyotrophic lateral sclerosis. Proteins: Structure, Function, and Bioinformatics 81:8, pages 1285-1303.
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Kasper P. Kepp. (2012) Bioinorganic Chemistry of Alzheimer’s Disease. Chemical Reviews 112:10, pages 5193-5239.
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Heather D. Durham, Edor Kabashi, David M. Taylor & Jeffrey N. Agar. 2006. The Proteasome in Neurodegeneration. The Proteasome in Neurodegeneration 247 264 .
Rina Takamiya, Motoko Takahashi, Yong Seek Park, Yoshie Tawara, Noriko Fujiwara, Yasuhide Miyamoto, Jianguo Gu, Keiichiro Suzuki & Naoyuki Taniguchi. (2005) Overexpression of mutated Cu,Zn-SOD in neuroblastoma cells results in cytoskeletal change. American Journal of Physiology-Cell Physiology 288:2, pages C253-C259.
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Noriko Fujiwara, Yasuhide Miyamoto, Kyoko Ogasahara, Motoko Takahashi, Takahisa Ikegami, Rina Takamiya, Keiichiro Suzuki & Naoyuki Taniguchi. (2005) Different Immunoreactivity against Monoclonal Antibodies between Wild-type and Mutant Copper/Zinc Superoxide Dismutase Linked to Amyotrophic Lateral Sclerosis. Journal of Biological Chemistry 280:6, pages 5061-5070.
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Michael R. Gunther, Reyna VanGilder, Jing Fang & Diana S. Beattie. (2004) Expression of a familial amyotrophic lateral sclerosis-associated mutant human superoxide dismutase in yeast leads to decreased mitochondrial electron transport. Archives of Biochemistry and Biophysics 431:2, pages 207-214.
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H. Volkel, M. Selzle, T. Walk, G. Jung, J. Link, A. C. Ludolph & A. Reuter. (2004) Reduced reactivation rate in mutant CuZnSOD and progression rate of amyotrophic lateral sclerosis. European Journal of Neurology 11:6, pages 397-404.
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Aaron Ciechanover & Patrik Brundin. (2003) The Ubiquitin Proteasome System in Neurodegenerative Diseases. Neuron 40:2, pages 427-446.
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Hao Zhang, Christopher Andrekopoulos, Joy Joseph, Karunakaran Chandran, Hakim Karoui, John P. Crow & B. Kalyanaraman. (2003) Bicarbonate-dependent Peroxidase Activity of Human Cu,Zn-Superoxide Dismutase Induces Covalent Aggregation of Protein. Journal of Biological Chemistry 278:26, pages 24078-24089.
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Rina Takamiya, Motoko Takahashi, Theingi Myint, Yong Seek Park, Nobuko Miyazawa, Takeshi Endo, Noriko Fujiwara, Haruhiko Sakiyama, Yoshiko Misonou, Yasuhide Miyamoto, Junichi Fujii & Naoyuki Taniguchi. (2003) Glycation proceeds faster in mutated Cu, Zn‐superoxide dismutases related to familial amyotrophic lateral sclerosis. The FASEB Journal 17:8, pages 1-18.
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Michel Dib. (2003) Amyotrophic Lateral Sclerosis. Drugs 63:3, pages 289-310.
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Makoto Urushitani, Junko Kurisu, Kayoko Tsukita & Ryosuke Takahashi. (2002) Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis. Journal of Neurochemistry 83:5, pages 1030-1042.
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Joan Selverstone Valentine. (2002) Do oxidatively modified proteins cause ALS?. Free Radical Biology and Medicine 33:10, pages 1314-1320.
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BARRY HALLIWELL. (2002) Hypothesis: Proteasomal Dysfunction. Annals of the New York Academy of Sciences 962:1, pages 182-194.
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Stefan I. Liochev & Irwin Fridovich. (2001) Copper,Zinc Superoxide Dismutase as a Univalent NO−Oxidoreductase and as a Dichlorofluorescin Peroxidase. Journal of Biological Chemistry 276:38, pages 35253-35257.
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Gayle A. Shinder, Marie-Claude Lacourse, Sandra Minotti & Heather D. Durham. (2001) Mutant Cu/Zn-Superoxide Dismutase Proteins Have Altered Solubility and Interact with Heat Shock/Stress Proteins in Models of Amyotrophic Lateral Sclerosis. Journal of Biological Chemistry 276:16, pages 12791-12796.
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Barry Halliwell. (2001) Role of Free Radicals in the Neurodegenerative Diseases. Drugs & Aging 18:9, pages 685-716.
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Takeshi Endo, Tsuneko Fujii, Kenzo Sato, Naoyuki Taniguchi & Junichi Fujii. (2000) A Pivotal Role of Zn-Binding Residues in the Function of the Copper Chaperone for SOD1. Biochemical and Biophysical Research Communications 276:3, pages 999-1004.
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